immunology basics Flashcards
1
Q
microbe
A
inflammation
2
Q
bacteria + virus
A
th1
3
Q
worms + allergens
A
th2
4
Q
food
A
treg
5
Q
asthma
A
th9
6
Q
extracellular microbes
A
th17
7
Q
costimulation most important in acute inflammation
A
cd86
8
Q
chemokine that will cause neutrophil trafficking
A
IL-8
9
Q
triggers T cells specific for antigen to produce IFNgamma
A
IL-12
10
Q
CD4+ T cells
A
helper T cells= secrete soluble molecules (cytokines) that help B cells to produce ABs and help Macrophages to destroy phagocytksed microbes
11
Q
IFNgamma (4)
A
- triggers B cells specific for the antigen to make IgG
- triggers antigen specific CD8 T cells to help kill pathogens
- IFNgamma upregulates MHC presentation and antigen processing and presentation
- IFNgamma directly inhibits viral replication
12
Q
CD8+ T cells
A
cytotoxic T lymphocytes = directly kill virus -infected cells and tumor cells
13
Q
T cells in Th1 response
A
CD8+ T cells // cytotoxic T lymphocytes
14
Q
T cells in Th2 response
A
CD4+ T cells // helper T cells
15
Q
IL associated w Th2
A
IL-4
