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MTLE > Immunology & Serology > Flashcards

Immunology & Serology Flashcards

1
Q

CD8 surface marker

A

Class I - Cytotoxic T cell

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2
Q

CD 4 surface marker

A

Class II - Helper T cell

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3
Q

antigen receptors on T lymphocytes bind HLA class II molecules with the help of which accessory molecule?

A

CD4

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4
Q

Most common anticoagulant in Apharesis

A

ACD

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5
Q

Expiry:

CPD, ACD, CP2D

A

21 days

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6
Q

Expiry:

CPDA-1

A

35 days

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7
Q

Expiry:
Additional solutions

A

42 days

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8
Q

Additional solutions

AS1:
AS3:
AS5:

A

AS1: Adsol
AS3: Nutricel
AS5: Optisol

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9
Q

AHG control cells are coated with

A

IgG antibodies

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10
Q

True or false?

AHG could be use for both DAT and IAT.

A

True

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11
Q

AHG is positive control for ____ reagents

A

Anti-IgG

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12
Q

AHG must be used to confirm all ______ antiglobulin reactions

A

negative

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13
Q

Cytotoxic T cells are usually CD_

A

CD8

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14
Q

Surface marker for mature T cells

A

CD2

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15
Q

_____ used in the identification of T cells where a T cells CD2 surface protein is bound to a sugar based LFA-3 homologue on the surface of a sheep red blood cell

A

E-rosetting

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16
Q

The term kernicterus means increased ______.

A

Unconjugated bilirubin

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17
Q

Kernicterus aka

A

Bilirubin encephalopathy

18
Q

Kernicterus shows >__ mg/dL of unconjugated bilirubin among infants with HDN

A

20

*causes acidosis and hypoalbuminuria

19
Q

What cell produces antibody?

A

Plasma cells

20
Q

Marker for plasma cells

A

CD38 & CD 138, CD27++

21
Q

Marker for Naive B cells

A

CD27-

22
Q

Marker for memory B cells

A

CD27+

23
Q

PCR technology can be used to ______ DNA.

A

Amplify small amounts of DNA

24
Q

Class 1 MHC presents antigen to

A

CD8 + T lypmhocytes

25
Q

Old Pan T

A

CD2 + T lymphocytes

26
Q

New Pan T

A

CD3 + T lymphocytes

27
Q

Whole blood collection procedure

If the volume collected is in the low volume range (300 to 404 mL in a 50 mL collection or 333 to 449 mL in a 500 mL collection), the unit must be labeled as a “________,” and fresh frozen plasma (FFP) cannot be made from this unit, as it would not contain adequate levels of coagulation factors.

A

low volume unit

28
Q

Parenterally means acquired from ____

A

blood

29
Q

Primarily transmitted parenterally

A

HGV (most)
HDV
HBV
HCV

30
Q

Disinfectant for BB blood collection

A

Iodine

31
Q

If patient is allergic to iodine use ______.

A

Chlorhexidine gluconate + Isopropyl alcohol

32
Q

In Blood donation collection, scrub in all direction about ___cm for ___ seconds.

A

4 cm
30 secs

33
Q

Blood donation collection

gauge:
angle:
Anticoagulant volume:
Ag to blood ratio:

A

gauge: 16
angle: 20°
Anticoagulant volume: 63 mL
Ag to blood ratio: 1:7

34
Q

Formula for the adjusted volume of blood to be collected and anticoagulant to be used.

Volume to collect:
Reduced volume of anticoagulant:
Amount of solution to be removed:

A

Volume to collect: (donor’s weight in Kg/50) x 50 mL

Reduced volume of anticoagulant: (Volume to collect/450) x 63mL

Amount of solution to be removed: 63 mL - calculated volume

35
Q

T or F?

Antigen-antibody reactions are reversible?

A

True

36
Q

When may an IS crossmatch be performed?

A

When there is no history of antibodies and the current antibody screen is negative.

37
Q

Antibody idiotype is dictated by the: (BOC)

A

Variable regions of heavy and light chains

38
Q

Which is TRUE about Anamnestic response?

a. Species specificity
b. Gradual increase in titer
c. First encounter with the antigen
d. Subsequent exposure to that same antigen

A

D

39
Q

All of the following are carcinogenic, EXCEPT

a. asbestos
b. radiation
c. organic herb

A

C

40
Q
A

MTLE (6 decks)

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