Immunopathology Flashcards
1
Q
Serum levels of complement proteins fall in SLE. Why do dis happen?
A
Complement binds to immune complexes
2
Q
What antibodies are virtually specific for scleroderma?
A
Nucleolar Abs, Scl-70, Anticentromere antibodies
3
Q
What matrix protein is deposited in Scleroderma?
A
Collagen
4
Q
What type of autoAbs are SSA and SSB?
A
Abs to soluble nuclear non-histone proteins
5
Q
What kind of hypersensitivity is Polyarteritis Nodosa?
A
Type III Hypersensitivity
6
Q
A patient has a positive antinuclear Ab test but no Ab against ds DNA. She also has pain and tingling in the tips of her fingers. What does she have?
A
Mixed Connective Tissue Disease
