immunosuppressant agents and chemotherapy

Question 1

dexamethasone
prednisone
methylprednisolone
steroids

Answer 1

decrease the normal immune system response, decrease inflammation
asthma, pulmonary diseases
spinal cord injury cerebral trauma (stroke)

Question 2

Mycophenolate mofetil

Answer 2

prevention and rejection

Question 3

cyclosporine

Answer 3

most common for prevention of rejection

only narrow therapeutic level draw a througth

Question 4

tracrolimus

Answer 4

prevention of rejection

Question 5

moromonab CD3

Answer 5

treat on going rejection

Question 6

organ rejection

Answer 6

SE of drugs Hypertension moderate to severe tremors, nephrotoxity, gingerval hyperplacia (overwrowth of he gums

Question 7

TDaP
Flu vaccine
Meningococcal vaccine

Answer 7

provide immunity

timeline for administration based on agent or disease

Question 8

antivenin
digoxin immune Fab
RH(D) immunoglobulin

Answer 8

agent formulated with immunoglobulin from humans or animals. They bypass host immune system to provide antibodies stat, provide treatment prevent disease or illness with exposure.

Question 9

bevacizumab

angiogenetic inhbitor

Answer 9

attacks angiogenesis (new blood vessel network) to destroy cancer cells

Question 10

methotrexate

antimetabolites

Answer 10

Substitutes for folic acid, purine, or pyrimidine AND. Inhibits enzymes critical in synthesis. Results in decrease synthesis of DNA, RNA.
USE: solid tumors– in the neck, head, liver
hematologic cancers– in the blood
autoimmune processes–RA
give drug with Leucovorin

Question 11

paclitaxel

Mitotic inhibitors

Answer 11

before or during mitosis to decrease cell division, by producing nonfunctional parts of cells.
Uses: solid tumors– in the neck, head, liver
hematologic cancer—in the blood

Question 12

topotecan

Topoisomerase inhibitors

Answer 12

Binds to DNA to topoisomerase 1 complex to impair relegation of DNA strand leads DNA strand to break.
USE: ovarian, colorectal cancer

Question 13

cisplatin

alkylating agents

Answer 13

alters cell’s DNA. the alkyl group attaches to DNA molecules and prevents correct bond
USE: combination chemotherapy treatment

Question 14

doxorubicin

cytotoxic antibiotics

Answer 14

inserts between two DNA strands DNA helix becomes unstable, blocks synthesis
USE: solid tumors, hematologic cancers

Question 15

general effects of cancer drugs

Answer 15

Nausea, vomiting, hair loss, fever, malaise, fatigue,

Renal damage, bone marrow suppression.

Question 16

dyphenhydramine

Answer 16

to treat allergic response to cancer patients

Question 17

dexamethasone

Answer 17

to decrease inflammatory response to cancer patients

Question 18

ondansetron

Answer 18

to decrease nausea and vomiting with cancer patients