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APMLE PREP > IMPORTANT GENES OF EMBRYOGENESIS > Flashcards

IMPORTANT GENES OF EMBRYOGENESIS Flashcards

1
Q

zone of polarizing activity at base of limb buds

anterior-posterior axis patterning, CNS development

mutations to holoprosencephaly

A

sonic hedgehog (SHH) gene

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2
Q

apical ectodermal ridge at distal end of each limb

dorsal ventral axis patterning, limb development

A

Wnt-7 gene

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3
Q

apical ectodermal ridge

limb lengthening via mitosis of mesoderm

A

fibroblast growth factor (FGF) gene

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4
Q

multiple

segmental org in cranial caudal direction, transcription factor coding

mutations leading to appendages in wrong locations. Isotretinoin leading to increased Hox gene expression

A

homeobox (Hox) gene

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APMLE PREP (99 decks)

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