Infection 3

Question 1

Treatment of GI infection
1st episode
2nd episode

Answer 1

1st Metronidazole
2nd vancomycin
§

Question 2

What is contraindicated in patients with C.diff

Answer 2

Loperamide

Question 3

Endocarditis treatment
+ What do add in MRSA resistant
+ What to add in Staphylococci
+ Benzylpenicillin

Answer 3

Amoxicillin +/- gentamycin
MSRA: Vancomycin
Staphylococci : Flucloxacillin
Streptococci : Benzylpenillcin

Question 4

Respiratory tract infection treatment CAP + length

• Low severity
• Moderate
• High severity

If staph
In strep

Answer 4

CAP (7) days (14-21) in Staph
Low severity: Amoxicillin
Moderate severity: Amoxicillin + Clarithromycin
High severity: Benzylpenicllin + Clarithromycin

If STAPH – flucloxacillin
If STREP – Benzylpenicillin
If MRSA – vancomycin

Question 5

Respiratory tract infection treatment HAP + length

• Less than 5 days
• More than 5 days

Answer 5

Early onset <5 days severe onset > 5 days

• Early onset: Co-amoxiclav / Cefuroxime
• Severe : antipseudomonal penicillin or broad spec cephalosporins or quinolone

Question 6

Treatment for Meningitis / Meningococcal / Septicaemia

Answer 6

Benzylpenicillin
Cefotaxime (in pen allergy)
Chloramphenicol (if immediate pen allergy

Question 7

Osteomyelitis treatment first line

Answer 7

Flucloxacillin

Question 8

Osteomyelitis treatment in penicillin allergy

Answer 8

Clindamycin

Question 9

What to give in eye infection

Answer 9

Chloramphenicol

Question 10

What to give in Impetigo

Answer 10

Fusidic acid + Flucloxacillin

Question 11

What to give in Cellulitis

Answer 11

Flucloxacillin

Question 12

What to give in Animal / Human bites

Answer 12

Co-amoxiclav or Doxycycline + Metronidazole

Question 13

What to give in MRSA (skin and soft tissue)

Answer 13

Tetracyclines / Sodium fusidate + rifampicin/ clindamycin

Question 14

What to give for oral treatment options

Answer 14

Metronidazole 200mg TDS

Question 15

What to give for sore throat and what to do if severe and what would you give for people with pen allergy q

Answer 15

Phenoxymethylpenicillin , if severe start with benzylpenicillin .
For pen allergy give clarithyromycin

Question 16

What to give for Sinusitis

Answer 16

Amoxicillin

Question 17

What to give for Otis externa

Answer 17

Flucloxacillin

Question 18

What to give for Otis Media

Answer 18

Amoxicillin

Question 19

TB treatment Phase 1 + length

Answer 19

RIPE 2 months 
Rifampicin 
Isonizaid 
Pyrazinamide
Ethambutol

Question 20

What is the patient counselling for 
Rifampicin 
Isoniazid 
Pyrazinamide 
Ethambutol

Answer 20

Rifampicin: enzyme inducter
Colours contact lenses look for hepatotoxicity
Isoniazid
Enzyme inhibitor , look out for signs of hepatotoxicity and it causes Peripheral Neuropathy
Pyrazinamide
Hepatotoxicity
Ethambutol
counselling: Visual changes report immediately

Question 21

TB treatment Phase 2 + length

Answer 21

RI

4 months

Question 22

Side effects of Ampthoterin

Answer 22

Fatal hepatotoxicity
Anaphylaxis with IV prep
Brand specific

Question 23

Side effect of Itraconazole

Answer 23

Hepatotoxicity + Heart failure

Question 24

Side effect of Ketoconazole

Answer 24

Fatal hepatotoxicity

Question 25

Side effect of Voriconazole

Answer 25

Photosensitivity and hepatotoxicity

Question 26

What to give for oral thrush

Answer 26

Nystatin / Miconazole

Question 27

What to give for vulva or vaginal thrush

Answer 27

Clarithromycin / Fluconazole

Question 28

What do you give for Tinea Miconazole

Answer 28

Clotrimazole or Terbinafine

Question 29

What do you give for Fungal nail infection

Answer 29

Amorolfine

Question 30

Oseltamivir
When do you use it
What group of people is most at risk of side effects
When do you start treatment

Answer 30

• Herpes Prophylaxis of influenza reduces symptoms by one day
• Over 65+.
• Start with 48 hours of symptoms or without symptoms on exposure

Question 31

BITE prevention (5)

Answer 31

• NETS
• DEET 20-50%
• Long sleeves and trousers
• Sunscreen first then DEET