infectious diseases AMK 21/05/2022 Flashcards

1
Q

gram postive bacilli

A
ABCD 
anthrax 
bacius 
clostridium 
diptheria 

gram negative cocci - neisseria

everything is gram I’ve bacilli

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2
Q

bactericidal

A

PENNYcilins - fluclox , amox
VANcomycin
CEPalosporis - cefrtiaxone van croos bbb

beta lactase

protein synthesis ribosomes - MC FAT
effective against gram negative
bacteriostatic - dont give to immunocompromised

macrocodes - mycin 
chloramphenicol -eye antibiotic 
fusidic acid 
aminoglycosdies - micin 
tetracyclins - doxycycline 

nucleic acid synthesis - ANTHONY QUINN
DNA
bacteriostatic

anti-folate - trimethoprim
quinolone - floxacin - ciproflxacin ( shuts down DNA synthesis , broad spectrum, anthrax poisoning)

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3
Q

diarrhoea( 3 or more unformed stools in 24hr)

Ix 
stool sample 
NAAT( PCR)
immunoassay for glutamate dehydrogenase 
immunoassay for toxins A and B 
GDH ove and PCR postive and toxins positive - active C diff infection 
GDH positive and toxin negative - potential carrier may be infection 
GDH and toxins negative is no C.diff

definitive treatment for c diff

recurrent c diff what do you do

A

PO vancomycin for c dif ( can’t take vancomycin IV will nerve reach gut)
IV metronidazole 2nd line
faecal transplant

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4
Q

Abx for osteomyelitis

A

clindamycin
goes IN to bones and Depp tissue penetrating
CI-IN-damycin

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5
Q

malaria - African country what organism transmits this

gambia

A

anopheles Gambiae

pallor fatigue and anaemia 
travel history - Nigeria 
splenomegaly 
jaundice to haemolysis  
fever 
anoxeria 
cause and vomit 
GI upset 
myalgia and arthralgia 

black water fervour - dark red urine from severe haemolytsis

blood film - gold standard investigation - 3thick and thin film within 36hours as a minimum
couissant

mx 
raiment 
malarone 
second line is quinine sulphate with doxycline or clindamycin 
severe - artesunate
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6
Q

exodus scapulairis

A

lymes disease

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7
Q

crushed ice an diarrhoea first line investigation

travellers - 10 day - main cause is E.coli then giardia , rotavirus most common children
acute - 14 day
persistent over 14

A

stool culture and MC&S

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8
Q

rice

A

bacillus cereus - cereal and rice

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9
Q

guillan barre syndrome

A

campylobacter

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10
Q

bloody diarrhoea docent sound sexy - SEECSY

A

salmonella e coli, entamoeba, campylobacter, shigella, yersinia

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11
Q

management of coli

A

rehydration

sometimes loperamide - anti diarrhoea

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