infectious diseases AMK 21/05/2022 Flashcards
gram postive bacilli
ABCD anthrax bacius clostridium diptheria
gram negative cocci - neisseria
everything is gram I’ve bacilli
bactericidal
PENNYcilins - fluclox , amox
VANcomycin
CEPalosporis - cefrtiaxone van croos bbb
beta lactase
protein synthesis ribosomes - MC FAT
effective against gram negative
bacteriostatic - dont give to immunocompromised
macrocodes - mycin chloramphenicol -eye antibiotic fusidic acid aminoglycosdies - micin tetracyclins - doxycycline
nucleic acid synthesis - ANTHONY QUINN
DNA
bacteriostatic
anti-folate - trimethoprim
quinolone - floxacin - ciproflxacin ( shuts down DNA synthesis , broad spectrum, anthrax poisoning)
diarrhoea( 3 or more unformed stools in 24hr)
Ix stool sample NAAT( PCR) immunoassay for glutamate dehydrogenase immunoassay for toxins A and B GDH ove and PCR postive and toxins positive - active C diff infection GDH positive and toxin negative - potential carrier may be infection GDH and toxins negative is no C.diff
definitive treatment for c diff
recurrent c diff what do you do
PO vancomycin for c dif ( can’t take vancomycin IV will nerve reach gut)
IV metronidazole 2nd line
faecal transplant
Abx for osteomyelitis
clindamycin
goes IN to bones and Depp tissue penetrating
CI-IN-damycin
malaria - African country what organism transmits this
gambia
anopheles Gambiae
pallor fatigue and anaemia travel history - Nigeria splenomegaly jaundice to haemolysis fever anoxeria cause and vomit GI upset myalgia and arthralgia
black water fervour - dark red urine from severe haemolytsis
blood film - gold standard investigation - 3thick and thin film within 36hours as a minimum
couissant
mx raiment malarone second line is quinine sulphate with doxycline or clindamycin severe - artesunate
exodus scapulairis
lymes disease
crushed ice an diarrhoea first line investigation
travellers - 10 day - main cause is E.coli then giardia , rotavirus most common children
acute - 14 day
persistent over 14
stool culture and MC&S
rice
bacillus cereus - cereal and rice
guillan barre syndrome
campylobacter
bloody diarrhoea docent sound sexy - SEECSY
salmonella e coli, entamoeba, campylobacter, shigella, yersinia
management of coli
rehydration
sometimes loperamide - anti diarrhoea