Information Flashcards
4 Types of Experimentation
1) Structure/function analysis
2) Comparison
3) Physiological measurement
4) Physiological manipulation
- Loss of function
- Gain of function
Capacitance
Current
Voltage
Conductance
Resistance
Capacitance (C) = ability to store charge
Current (I) = movement of charge
Voltage (V) = difference in charge
Conductance (G) = how easily charges can move
Resistance (R) = how difficult it is for charges to move
2 Conditions for Creating Voltage
1) Ionic concentration difference
2) Selective ion permeability
Why does action potential move in one direction?
1) Voltage gated Na+ channels inactivate after action potential is reached
2) K+ channels create an undershoot
Refractory Period (2 Types)
- Period where the neuron has a difficulty of starting a second action potential
Absolute: inactivation of the Na+ channel occurs. To get them active again, voltage has to be dropped to activate and close the channel. Na+ channel can be saved for later use.
Relative: voltage gated K+ channel opens. When opened, the voltage is pushed down toward K+ equilibrium. To get another action potential, need to fight against this counter acting action.