inheritance Flashcards
What are chromosomes
thread like structures of DNA carrying genetic information in the forms of genes located in nucleus. double helix supercoils to form structures called chromosomes
How many chromosomes does the human body have
Ordinary human body cells contain 23 pairs of chromosomes. Each chromosome pair is called a homologous pair
What is the 23rd pair of chromosomes called
sex chromosomes
In females, the sex chromosomes are the same, a homozygous genotype (XX)
In males, the sex chromosomes are different, a heterozygous genotype (XY)
How many chromosomes do Gametes contain
Gametes contain just 23 individual chromosomes
What processes rely on DNA
Cell division and protein synthesis both rely on these base-pairing rules because each half of the DNA double helix acts as a template to be copied in order to create a complete new double helix
What is DNA
Genetic material found in the nucleus of a cell. The strands are formed from a sugar phosphate backbone with bases joined together by complementary base pairing
Adenine pairs with thymine
Guanine pairs with cytosine
What is the structure of RNA
the nucleic acid RNA (ribonucleic acid) is a polynucleotide – it is made up of many nucleotides linked together in a long chain
What are the similarities between RNA and DNA structures
RNA nucleotides contain the nitrogenous bases adenine (A), guanine (G) and cytosine (C).
RNA polynucleotide strand is made up of alternating ribose sugars and phosphate groups linked together, with the nitrogenous bases of each nucleotide projecting out sideways from the single-stranded RNA molecule.
RNA molecule is messenger RNA (mRNA), which is the transcript copy of a gene that encodes a specific polypeptide. Two other examples are transfer RNA (tRNA) and ribosomal RNA (rRNA)
What are the differences between RNA and DNA structure
RNA nucleotides never contain the nitrogenous base thymine (T) – in place of this they contain the nitrogenous base uracil (U). RNA nucleotides never contain the nitrogenous base thymine (T) – in place of this they contain the nitrogenous base uracil (U)
What is a gene
A gene is a sequence of nucleotide bases in a DNA molecule that codes for the production of a specific sequence of amino acids, that in turn make up a specific polypeptide (protein)
What are the stages of protein synthesis
Transcription – DNA is transcribed and an mRNA molecule is produced
Translation – mRNA (messenger RNA) is translated and an amino acid sequence (protein) is produced
What is Transcription
This stage of protein synthesis occurs in the nucleus of the cell
Part of a DNA molecule unwinds (the hydrogen bonds between the complementary base pairs break)
This exposes the gene to be transcribed (the gene from which a particular polypeptide will be produced)
A complementary copy of the code from the gene is made by building a single-stranded nucleic acid molecule known as mRNA (messenger RNA)
The mRNA molecule leaves the nucleus via a pore in the nuclear envelope
What is translation
his stage of protein synthesis occurs in the cytoplasm of the cell
After leaving the nucleus, the mRNA molecule attaches to a ribosome
In the cytoplasm, there are free molecules of tRNA (transfer RNA)
These tRNA molecules have a triplet of unpaired bases at one end (known as the anticodon) and a region where a specific amino acid can attach at the other
There are at least 20 different tRNA molecules, each with a specific anticodon and specific amino acid binding site
The tRNA molecules bind with their specific amino acids (also in the cytoplasm) and bring them to the mRNA molecule on the ribosome
The triplet of bases (anticodon) on each tRNA molecule pairs with a complementary triplet (codon) on the mRNA molecule
Two tRNA molecules fit onto the ribosome at any one time, bringing the amino acid they are each carrying side by side
A peptide bond is then formed between the two amino acids
This process continues until a ‘stop’ codon on the mRNA molecule is reached – this acts as a signal for translation to stop and at this point the amino acid chain coded for by the mRNA molecule is complete
This amino acid chain then forms the final polypeptide (protein)
What is a gene
A gene is a short length of DNA found on a chromosome that codes for a particular characteristic
What are Alleles
Alleles are variations of the same gene
As we have two copies of each chromosome, we have two copies of each gene and therefore two alleles for each gene
One of the alleles is inherited from the mother and the other from the father