Inhibidores De La Sintesis Proteica Bacterianaa Flashcards

1
Q

Cuales son los inhibidores de la subunidad ribosomal 50s?

A
  1. Macrólidos (Azitromicina, Eritromicina y Claritromicina)
  2. Fenicoles (Cloranfenicol)
  3. Lincosamidas (Clindamicina)
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2
Q

Inhibidores de la subunidad ribosomal 30s?

A

Aminoglucosidos (amikacina y gentamicina)
Tetraciclinas (doxiciclina)

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3
Q

Indicaciones de los macrolidos?

A

Infecciones del tracto respiratorio

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4
Q

Mecanismo de accion de los macrolidos

A

Inhiben la actividad de la transpeptidasa

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5
Q

Inhiben al CYP3A4

A

Claritromicina y Eritromicina

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6
Q

Azimtromicina se da en

A

Influenzae
Otitis media
Infecciones en la piel
Tos ferrina: Bordetella Pertusis
Helycobacter pilory

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7
Q

Claritromicina se da en

A

Muraxella cathrlis

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8
Q

RAM de los macrolidos

A

Gastrointestinales
Prolongacion del QT

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9
Q

Mecanismo de accion del cloranfenicol

A

Inhibidor de la sintesis proteica 50s

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10
Q

RAM del cloranfenicol

A

Sx del niño gris

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11
Q

Indicaciones del cloranfenicol

A

Meningitis

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12
Q

Mecanismo de accion de la clindamicina

A

Inhibidor de la subunidad 50s

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13
Q

Utilizan la difusion facilitada

A

Gemtamicina y Amikacina

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14
Q

Mecanismo de accion de los aminoglucosidos (gentamicina y amikacina)

A

Imhibrn la subunidad ribosomal 30s

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15
Q

Indicaciones de los aminoglucosidos

A

Pielonefritis
Peritonitis

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16
Q

Mecanismo de accion de las tetraciclinas (doxiciclina)

A

Rvitan q el arn se vaya al sitio del receptor e inhiben a la sintesis de la subunidad 30s

17
Q

Efecto adverso de la eritromicina

A

Aumenta la motilidad

18
Q

Con que se asocia la clindamicina

A

Clostridium difficile