Inhibition Flashcards
What are enzyme inhibitors
What is competitive inhibition
What is the pathway of competitive inhibition
What is the equation for the initial velocity for an uninhibited reaction
What is the equation for the dissociation constant for the inhibitor
Derive the equation for the Michael’s menten equation which describes the inhibitor
What is the Michaelis menten equation which describes the inhibitor
What is Vmax.app and Km.app
What does a larger value of alpha mean for Vmax
Draw Michaelis - menten plot for competitive inhibition and recall the information you can obtain from it
Draw line weaver-burk plot for competitive inhibition and recall the information you can obtain from it
What is uncompetitive inhibition
What does alkaline phosphatase do and how does it work
What is the reaction pathway for uncompetitive inhibition
What is the effect of a high concentration of [S] on Vmax with uncompetitive inhibition reaction
What is the equation for the rate for uncompetitive inhibition
What is the effect of uncompetitive inhibition on Km
Draw the Michaelis- menten plot for uncompetitive inhibition and the information you can obtain from it
Draw the line weaver-burk plot for uncompetitive inhibition and the information you can obtain from it
What is mixed inhibition
What is the pathways for mixed inhibition
What are the 2 equations for the dissociation constant for mixed inhibition
What is the equation for initial velocity for mixed inhibition
Draw the lineweaver burk plot for mixed inhibition and what information can you obtain from it
What is non competitive inhibition
What are the special cases for mixed inhibition
What is the pathway for mixed inhibition
Draw the Michaelis menten plot for mixed inhibition recall and the information you can obtain from it
Draw the lineweaver-burk plot for mixed inhibition recall and the information you can obtain from it
Draw a table summarising the different types of inhibition and their effects on Vmax.app and Km.app
What are the 4 types of reversible suicide
What is group-specific covalent modifying agents
What are affinity labels
What are suicide substrates
How does penicillin work
What is the most important part of penicillin and what are the different derivatives of penicillin
What are transition state analogues
What do HIV proteases do
