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Foundations Week 4 > inhibitorsproteinsynthesis > Flashcards

inhibitorsproteinsynthesis Flashcards

1
Q

inhibitors of 30S

A

Aminoglycosides and Tetracycline

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2
Q

Inhibitors of 50 S

A

Linezolid, macrolides, chloramphenicol, clindamycin, and quinprisinte/dalfopristin

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3
Q

Inhibit Elongation

A

Aminoglycoside, Tetracycline, Macrolide, Chloramphenical, clindamycin, quinupristin/daloprisin

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4
Q

contraindicated in newborns

A

chloramphenicla, erythromycin

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5
Q

Not to be used in children

A

Tetracyclines, Flouroquinolones

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6
Q

Avoid during pregnancy

A

Tetracycline, Aminoglycoside, Clarithromycin, Flouroquinolones, Chloramphenicol

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7
Q

Cause hemolysis with G-6P DH deficiency

A

Sulfonamides

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8
Q

Toxic to hepatocytes

A

Rifampin

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9
Q

Nephrotoxic

A

Sulfonamides, Aminoglycosides, Vancomycin

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10
Q

Cause QT interval prolongation

A

macrolides, flouroquinoloines

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11
Q

Disulfriam like reaction with alchohol

A

metronidazole, 2nd genCephalosporin

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12
Q

Common drugs to be sensitive to

A

sulfonamides, Beta Lactams

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13
Q

2 bacteriocidal inhibitors of pretein synthesis

A

Aminoglycosides, Flouroquinolones

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14
Q

Resistance via increased efflux

A

Tetracycline, macrolides, Streptogramins, Sulfonamides, Flouruquinolones

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15
Q

Reserved for multiple drug resistanc gram (+) bacteria

A

Streptogramins

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16
Q

Toxic antibitoics, cause gray baby syndrome

A

Chloramphenical

17
Q

Treats aerobic and anaerobic, also good for acne

A

Clindamyacin

18
Q

Can cause superinfection and C. diff

A

Clindamycin

19
Q

the 5 aminoglycodsides

A

Gentimcin, neomycin, amikacin, tobramycin, streptomycin

20
Q

Effective only again gram (-)

A

Aminoglycosides

21
Q

Aminoglycisides used for pseudomonas

A

Amikacin

22
Q

4 Tetracycline drugs

A

tetracycline, doxycycline, minocycline

23
Q

This drug is administered at a dose up to 10 times the MIC

A

Aminglycosides

24
Q

used for gram(+) including MSRA and Vancomycin Resistant entercocci

A

linezolid

25
Q

Antibody that inhibits tRNA

A

Tetracyclin

26
Q

Commonly used for respiratory infections

A

Macrolides

27
Q

Nephro and ototoxic

A

Aminoglycosides

28
Q

Causes bone marrow suppression

A

Linezolid and Chlorampenicol

29
Q

Form chelates with metal ions

A

tetracycline

30
Q

Treats chlamydia

A

Macrolides

31
Q

The Macrolides

A

Erythromycin, Azithromycin, Clarithromycin

Foundations Week 4 (4 decks)

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