Key counseling points

Question 1

Most antibiotics can be taken with food to decrease Gl upset - Exceptions:

Answer 1

Take on an empty stomach: ampiciliin oral capsules and suspension, ceftibuten suspension, levofloxacin
oral solution, penicillin VK, rifampin, isoniazid, itraconazole solution’, voriconazole*

Take w ithin one hour of finishing a meal: amoxicillin ER

Question 2

1:1 IV TO ORAL DOSING

For these drugs, the oral and IV doses are the same.

Answer 2

Levofloxacin, moxifloxacin
Doxycycline, minocycline
Linezolid, tedizolid
Metronidazole
Sulfamethoxazole/Trimethoprim
Fluconazole*, isavuconazonium*, posaconazole* (oral tablets and IV), voriconazole*

Question 3

LIGHT PROTECTION DURING ADMINISTRATION

Answer 3

Doxycycline
Micaf ungin*
Pentamidine*

Question 4

Compatible with dextrose only

Answer 4

Quinupristin/Dalfopristin
Sulfamethoxazole/Trimethoprim
Amphotericin B* (conventional, Abelcet, Ambisome)
Dalbavancin, oritavancin
Pentamidine*

Question 5

Compatible with saline only

Answer 5

Ampiciliin
Ampicillin/Sulbactam
Ertapenem
Daptomycin (Cubidn RF)

Question 6

Compatible with NS/LR only

Answer 6

Caspofungin*

Daptomycin (Cubicin)

Question 7

Doxycycllne (oral)

Answer 7

Take with a full glass of water and remain upright for 30

minutes after the dose to avoid GI irritation.

Question 8

QUINOLONES

Can cause:

Answer 8

□ CNS effects, including seizures.
□ Hypo/hyperglycemia.
□ Peripheral neuropathy.
□ Photosensitivity.
□ QT prolongation.

Question 9

MACROLIDES

Can cause:

Answer 9

□ GI upset.

□ QT prolongation.

Question 10

QUINOLONES

Answer 10

■ Avoid in pregnancy, breastfeeding and children.

■ Drug interactions due to binding.

Question 11

TETRACYCLINES

Answer 11

■ Avoid in pregnancy, breastfeeding and children < 8 years old.
■ Drug interactions due to binding.
■ Can cause photosensitivity.

Question 12

SULFAMETHOXAZOLE/TRIMETHOPRIM

■ Avoid in:

Answer 12

□ Pregnancy or breastfeeding.

□ Sulfa allergy.

Question 13

SULFAMETHOXAZOLE/TRIMETHOPRIM

Can cause:

Answer 13

□ Photosensitivity.

□ Crystals in the urine. Take with a full glass of water.

Question 14

METRONIDAZOLE

■ Avoid

Answer 14

■ Do not use any alcohol products while using this medication, and for at least three days afterward.

Question 15

METRONIDAZOLE

■ Can cause:

Answer 15

□ Nausea.

□ Metallic taste in the mouth.

Question 16

NITROFURANTOIN

Answer 16

■ Take with food to decrease nausea.

Question 17

NITROFURANTOIN

■ Can cause:

Answer 17

□ Nausea

□ Brown discoloration of urine (temporary and harmless).