Kidney Disease Flashcards
What is microalbuminuria
30-300 mg/gtoo small to show up in dipstickshows early damage to kidney - time to treat! Delay or stop progression of damage
What is proteinuria?
300-1000mg of Albumindipstick will turn positiveProtein to Cr ratio will be 1-2
What does 4+ proteinuria indicate?
nephrotic!
What causes transient proteinuria?
exercise, fever, postural proteinuria, dehydration, cold exposure, stress
Criteria for nephrotic syndrome
- Al/Cr range >4
- Edema
- Decreased serum albumin
- Reflexive hyperlipidemia
What are the major classifications of nephrotic syndrome?
Diabetes, Lupus, Drugs, InfectionsHTN does not cause nephrotic syndrome
Stages of CKD
- 1 – protein in urine, normal GFR >90
- 2 – protein in urine GFR 60-89
- 3a – GFR 45-59
- 3b – GFR 30-44
- 4 – GFR 15-29
- 5 – FGR
must persist >3mo
CKD and salt
for BP control, almost always need salt restriction: 2 g/day
CKD and protein
Protein:
- St 1-2: no restriction
St 3-4: restrict - high protein also –> high salt, aci precursors, phosphates. Can lead to metabolic acidosis, hyperkalemia, hyperphospathemia, edema, HTN, uremic sx
Recommended: 0.8 g protein/kg ofideal body weight(actual wt may be d/t edema or obesity)
if uremic sx persist - 0.6g/kg/day
CKD and caloric intake
St 3-4:
Medication assessment for CKD patient should include
At every visit:
- Dosage adjustment based on level of kidney function;
- Detection of potentially adverse effects on kidney function or complications of chronic kidney disease;
- Detection of drug interactions;
- Therapeutic drug monitoring, if possible.
(KDOQI)
What is theClassification of Kidney Disease Outcome Quality Initiative?
through the NKFThis program providesevidence-based guidelines for all stages of chronic kidney disease (CKD) and related complications