L14 - Adrenal Gland part 3 Flashcards

1
Q

Medulla arises from which embryonic structure

A

ectoderm

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2
Q

catecholamines are produced by what cells and where

A
  • chromatin cells

- in adrenal medulla

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3
Q

Describe what occurs during a stressful situation

A
  • sympathetic fibre stimulation
  • depolarisation of adrenal-medullary chromaffin cells
  • secretion of norepinephrine and epinephrine into blood stream
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4
Q

chromaffin cell tumour

A

pheochromocytoma

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5
Q

classic triad of symptoms for adrenal pheochromocytoma

A
  • episodic headache
  • generalised sweating
  • tachycardia
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6
Q

what are paragangliomas ?

A
  • extra adrenal pheochromocytoma’s

- RARE

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7
Q

neurofibromatosis type 1

A
  • familial tumour
  • autosomal dominant with mutations in NF1 GENE
  • skin tags
  • cafe-au-lait spots
  • bony abnormalities
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