L26 Embolism Flashcards
Definition of infarction
• An area of ischaemic necrosis caused by occlusion of either the arterial supply OR the venous drainage in a particular tissue.
Define shock
Shock is a situation in which the organs and tissues of the body are not receiving an adequate flow of blood.
What is an embolus?
is the transfer of undissolved material in the bloodstream and its impaction in a distant vessel.
Detached thrombosis most commonly becomes an embolus.
Detached intravascular solid, liquid or gaseous mass carried by blood to site distant from its point of origin.
Pulmonary Embolism PE
Most likely arises(95%) from DVT:
- above the knee
- through venous circulation
- right heart
- pulmonary vasculature
Obstruction of small end arteries causes infarction
What are the factors that lead to the development of an infarction?
1) Nature of vascular supply
2) Rate of occlusion development
3) Vulnerability to hypoxia
4) O2 content of blood
What are the causes of shock?
MI
haemorrhage
extensive trauma
large PE pulmonary embolism
What are the stages of shock?
Nonprogressive
Progressive
Irreversible
What is paradoxical embolism?
Emboli arises in the vein and end up in arterial circulation bc heart defects