Lecture 3 - T Cell mediated immunity part 2

Question 1

Th1
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 1

IL-12, IFN-Gamma
T-bet
IL-12, IFN-Gamma

Question 2

Th2
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 2

IL-4
GATA3
IL-4, IL-5, IL-13

Question 3

Th9
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 3

IL-12, IFN-Gamma
PU.1
IL-9

Question 4

Th17
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 4

IL-,6 IL-21, IL-23
RORyT
IL-6, IL-17

Question 5

Th22
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 5

IL-6, IL-23 TNF-Alpha
AHR
IL-13, IL-22

Question 6

Tfh
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 6

IL-16, TGF-B, IL-23
Bcl6
IL-21

Question 7

Treg
Cytokines that induce differentiation:
Defining transcription factor:
Characteristic cytokines:

Answer 7

TGF-B
FoxP3
TGF-B, IL-10