Lecture 4: Drug Selectivity and Allostery Flashcards
1
Q
What is meant by selectivity and how do you determine selectivity?
A
2
Q
Why is the pharmaceutical industry is concerned with drug
selectivity?
A
3
Q
What is the structural basis for selectivity, and how can allosteric sites be exploited for selectivity?
A
4
Q
How can allostery be detected by cooperativity?
A
5
Q
How can disease be caused by improper regulation by allosteric
effectors, as well as improper catalytic activity?
A
