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HISTOPATH LEC > LESSON 5 > Flashcards

LESSON 5 Flashcards

1
Q

Involves in the transformation in one type of
adult cell to another.

A

Metaplasia - Reversible

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2
Q
  • means “disordered growth”; presence of
    abnormal cells within a tissue (reversible)
A

Dysplasia

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3
Q

Lack of differentiation of cells
(irreversible)
➔ Usually utilized as a criteria towards
malignancy
➔ One of the basis or starting baseline for
diagnosing a malignancy

A

Anaplasia

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4
Q

means “new growth”; uncontrolled
proliferation of cells with no purpose; →
Tumor/Neoplasms
➔ Can lead to tumor or formation of tumor
➔ Continuous abnormal proliferation

A

Neoplasia

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5
Q

Mass of neoplastic cells
○ Resembles the normal cells
○ Sometimes it can be unidentifiable and
sometimes the degree of differentiation is
identifiable

A

Tumor/Neoplasm

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6
Q

incomplete development of the
organ

A

Aplasia

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7
Q

failure of an organ to develop
fully

A

Hypoplasia

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8
Q

complete non-appearance of an
organ

A

Agenesia

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9
Q

Type of abnormality in which the organs or a part of
the tissue is smaller than normal

A

RETROGRESSIVE

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10
Q

May resemble and function like a normal cell
● _______________; non-responsive to normal growth
factors
●____________nature; competes with cells for metabolic
needs

A

Autonomous
Parasitic

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11
Q

Acquired decrease of the size of a normally
developed organ

A

Atrophy

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12
Q

failure of an organ to form an
opening

A

Atresia

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13
Q

increased in tissue size due to
the increase in the size of individual cells.

A

Hypertrophy-

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14
Q

increased size of organ or
tissue due to increase in the number of
cells

A

Hyperplasia-

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15
Q

Developmental
Progressive
Degenerative

A

Developmental
○ Aplasia
○ Hypoplasia
○ Agenesia
○ Atresia
Progressive
● Hypertrophy
● Hyperplasia
Degenerative
● Dysplasia
● Metaplasia
● Anaplasia
● Neoplasia

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15
Q

It is an active element of the tumor

A
  1. Parenchyma (actively dividing)
16
Q

➔ The connective tissue framework with the
lymphatic and vascular channels

A
  1. Stroma (body)
17
Q

CLASSIFICATION OF TUMOR
1. __________ - non cancerous
2. ___________ - cancerous type of tumor

A

Benign
Malignant

18
Q

● Only individual, discrete well-formed glands

A

Grade 1

19
Q

Predominantly well-formed glands with
lesser component of poorly formed,
fused, and/or cribriform glands

A

Grade 2

20
Q

Predominantly poorly formed, fused,
and/or cribriform glands with lesser
component of well-formed glandsc

A

Grade 3

21
Q

Only poorly formed, fused, and/or

cribriform glands or
● Predominantly lacking gland formation
and lesser component of well-formed
glands (but poorly formed, fused,
and/or cribriform glands can be a minor
component)

A

Grade 4

22
Q

Lack gland formation - or has glands
with necrosis - with or without poorly
formed, fused, and/or cribriform glands

A

Grade 5

23
Q

“Self-destruction”; the self-digestion of the cells by
their own enzymes;
○ First external signs is the whitish appearance
of cornea

A

AUTOLYSIS

24
Q

Greenish blue discoloration with odor

A

PUTREFACTION

25
Q

General drying and wrinkling of fluid-filled organs

A

DESICCATION

26
Q

PUTREFACTION

The dead body will have a foul smell as they release
gas due to the invasion of the tissue by a bacteria
called _____________ which is responsible for
the odor of the dead body.

A

Clostridium welchii,

27
Q

Purplish discoloration of skin to blood stasis;
differentiated from ecchymosis
➔ For this one, there is discoloration
➔ A purplish discoloration due to the stoppage of blood
circulation

A

LIVOR MORTIS

28
Q

______________- this is due to death
______________ - this is due to death
this is due to ecchymosis

A

➔ Post Mortem Clot
➔ Ante Mortem Clot

29
Q

Occurs immediately after death; apparent only in
autopsy

A

POST MORTEM CLOTTING

30
Q

Stiffening of muscles due to lack of ATP
This refers to riginity or stiffening of the muscles
➔ This type of change is first seen in the muscles of the
head and on the neck. After that, it will spread
towards the lower extremities, and subsequently
disappear in the same sequence.
➔ This is due to lack of ATP

A

RIGOR MORTIS

31
Q

is responsible for delivering calcium
ions back to the sarcoplasmic reticulum of
the muscles

A

ATP

32
Q

NO ATP = __________________

A

NO RELAXATION OF MUSCLES

33
Q

application of pressure

A

Blanching test -

34
Q
A

HISTOPATH LEC (6 decks)

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