Lipid Lowering Drugs Flashcards by jada Yates | Brainscape

Q

HMG-CoA reductase inhibitors are also called?

A

Statins

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Q

Statins: mechanism of action

A

lower the rate of cholesterol production

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Q

What is a benefit of statins?

A

they can raise HDL levels

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Q

Main adverse effects of statins?

A

muscle pain (myalgia) and liver injury

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Q

Can satins be used in pregnancy?

A

no

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Q

How does liver injury occur with statins?

A

due to elevation in liver enzymes

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Q

Statins should be used cautiously in people with?

A

current liver dysfunction (hepatitis)

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Q

Statins should not be taken with?

A

Grapefruit juice

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Q

Statin that is vey sensitive to grapefruit juice?

A

lovastatin

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Q

what is the biggest non-modifiable risk factor for CAD?

A

LDL/HDL ratio

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