Maguire (Brain Plasticity) Flashcards
What area is this study part of
Biological area
What is a key theme of this study
Brain plasticity
Define brain plasticity
Brains ability to reorganise itself in response or environmental stimulus
What is the background of the study (2)
Research shows the lesions to hippocampus affect a persons ability to remember the location if different places and things
In some species of animals the hippocampal volume enlarges during seasons of hen spatial ability is greatest
What was the research method
Quasi experiment because Iv was naturally occurring ( whether they were taxi drivers or not)
What was the independent variable
Whether or not they were London taxi drivers or not
What was the dependent variable
The volume of hippocampi including the anterior, body and posterior regions
How was the DV measured
Analysing MRI scans of the participants brains using the 2 techniques of VBM and pixel counting
What was the design
Independent measures + matched participants
What was the sample of taxi drivers
(3)
16 healthy, right handed, male London taxi drivers
Mean age 44 range of 32 to 62
Mean time licenced taxi driver = 14.3 years
What was the sample of non taxi drivers
(4)
Control group
50 for VBM analysis
16 for pixel counting
Matched for health, handedness, mean age, age range and sex
Describe the procedure of the study
The scans of control group selected from structural mri scan data base at same unit as taxi drivers
VBM analysis - automatic procedure that normalises scans so it eliminates overall brain size as a variable and identifies differences in grey matter / density in different regions of the brain
Pixel counting analysis - compares to the volume of anterior, body and posterior cross sections of taxi drivers hippocampi
Images analysed by one person experienced in the technique - they didn’t know if it was a taxi driver or not
Total hippocampi volume measured
What were the results from the VBM
No significant differences in the brains except
Taxi drivers had significantly increased grey matter in right and left posterior hippocampi
Controls had greater grey matter volume in right and left anterior hippocampi
What were the results from the pixel counting
No significant difference in overall volume of hippocampi
Taxi drivers had significantly greater posterior hippocampal volume
Controls had greater anterior right hippocampal volume
Greater hippocampal volume in right than left in both taxi drivers and controls
What are 3 conclusions from the study
Changes in the arrangement of hippocampal grey matter occur due to nurture
Plasticity in the structure do human brain due to prolonged environmental stimuli
Regionally specific structural differences in the hippocampu of taxi drivers vs non taxi drivers