Major Innate Immune Cells

Question 1

Natural Killer Cells

Answer 1

Kills cells infected with certain viruses; also protect against tumors; interferon gamma; macrophage activation

Question 2

Neutrophil

Answer 2

Phagocytosis and killing of microorganisms; most abundant type of granulocyte (whit blood cell); ROS and RNS; antimicrobial peptides

Question 3

Eosinophil

Answer 3

Killing of antibody-coated parasites through release of granule contents

Question 4

Basophil

Answer 4

Controlling immune responses to parasites

Question 5

Dendritic Cell

Answer 5

Activation of T cells and initiation of adaptive immune responses; “Bridge” between innate and adaptive immunity; most powerful APC; costimulatory signals; ROS; interferon; cytokines

Question 6

Mast Cell

Answer 6

Expulsion of parasites from body through release of granules containing histamine and other active agents

Question 7

Monocyte

Answer 7

Circulating precursor cell to macrophage

Question 8

Macrophage

Answer 8

Phagocytosis and killing of microorganisms. Activation of T cells and initiation of immune responses; antigen presentation; ROS and RNS; cytokines; complement proteins; inflammatory mediators