malignant bone tumoues Flashcards

1
Q

osteosarcoma

A

malignant bone tumour that produces bone

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2
Q

symptoms of osteosarcoma

A

constant pain
worse at night
fatigue
weight loss

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3
Q

treatment for osteosarcoma

A

chemotherapy

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4
Q

age of those with osteosarcoma

A

young adults

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5
Q

where is osteosarcoma found

A

commonly the knee

spread haematogenously

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6
Q

chromosome translactchondrosarcoma

A

cartilidge producing primary bone tumour

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7
Q

symptoms of chondromsarcoma

A

sciatica
back pain
bladder pain
unilateral oedema

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8
Q

where is the chondrosarcoma most commonly seen

A

proximal femur and pelvis

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9
Q

who is affected by chondrosarcoma

A

older patients- around 45

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10
Q

treating chondrosarcoma

A

symptsurgery- resection

no chemo or radio

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11
Q

chondrosarcoma- spread

A

very large and slow to spread

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12
Q

ewings syndrome

A

small round blue cell tumour

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13
Q

causes of ewings syndrome

A

chromosome translocation between chromosome 11 and 22- weings sarcoma gene on 22

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14
Q

symptoms of ewings sarcoma

A

fever
raised inflammatory markers
warm swellings at site

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15
Q

where ewings syndrome effects

A

long bones

femur

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16
Q

who ewings syndrome effects

A

teenagers

17
Q

treating ewings sydnrome

A

chemo or radio

18
Q

how ewings syndrome looks

A

onion skin appearance

19
Q

lymphoma

A

cancer of the round cells of the lymph system and macrophages

20
Q

symptoms of lymphoma

A
lymphadenopathy
night sweats 
weight loss
fatigue
fever
21
Q

treating lymphoma

A

non aggressive- wait and watch
agrresive- chemo
hodhkins- radio

22
Q

myeloma

A

clonal proliferation of abnormal plasma cells wwhich arise from bone marrow

23
Q

symptoms of myeloma

A
anaemia
weight loss
fatigue
bone pain
back pain
24
Q

age of someone with myelona

A

45 to 65

25
Q

types of myeloma

A

plasmacytoma

multiple myeloma

26
Q

treatment for myleoma

A

plasmacytoma- radio

multiple myeloma- chemo

27
Q

diagnosing myeloma

A

plasma protein electrophoresis

early morning urine collection for bence protein assay

28
Q

myeloma on bone scan

A

no mets may be sseen as lack osteoblastic response

29
Q

worst prognosis

A

ewings syndrome

30
Q

bone mets examples

A
breast cancer
prostate cancer
lungs
renal cell
thyroid