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From Flashcardlet > med PNS d/o > Flashcards

med PNS d/o Flashcards

0
Q

Other name for endoneurium

A

Henle’s sheath

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1
Q

Difference of reflexes in PNS and CNS

A

CNS: hyper reflexia, primitive reflexes
PNS: hypo to areflexia

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2
Q

Cell that provides myelin in a 1:1 ratio

A

Schwann cell (PNS)

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3
Q

Responsible for proprioception and vibration

At posterior column

A

Large fibers

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4
Q

Responsible for pain and temperature

At anterior column

A

Small fibers

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5
Q

Conduction velocity: 50m/sec

A

Peripheral nerves

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6
Q

Conduction velocity: 70-100m/sec

A

Spinal descending tract

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7
Q

Conduction velocity: 20m/sec

A

Auditory nerve

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8
Q

Nerve pathology for autoimmune d/o
Injuries
Compression

A

Mononeuropathy

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9
Q

Nerve pathology of diabetes, heavy metals, alcohol, vincristine, B12 deficiency

A

Polyneuropathy

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10
Q

Nerve pathology where distal nerves are more affected than proximal nerves

A

Polyneuropathy

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11
Q

Nerve pathology that occur in multiple nerve injuries in different locations

A

Mononeuritis multiplex

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12
Q

Nerve pathology in vasculitis, lupus, sarcoid, diabetes

A

Mononeuritis multiplex

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13
Q

Nerve pathology that affects lumbo-sacral

A

Plexopathy

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14
Q

Nerve pathology in brachial plexus neuritis, trauma

A

Plexopathy

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15
Q

Causes of nerve injury in GBS, CIDP, compression and entrapment injuries

A

Demyelinating

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16
Q

Neuropathy in paraneoplastic syndrome

Dorsal root ganglia

A

Pure sensory neuropathy

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17
Q

Neuropathy in diabetes

Pain and temperature sense

A

Small fiber neuropathy

Autonomic neuropathy

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18
Q

Physiologic block without anatomic disruption

Spontaneously recovers

A

Neuropraxia

19
Q

Anatomic interruption of axon

Wallerian degeneration

A

Axonotmesis

20
Q

New axon regenerates away from the cell body

1mm per day

A

Wallerian degeneration

21
Q

Complete anatomical disruption of axon and all surrounding CT
Mgt: grafting
No regeneration

A

Neurotmesis

22
Q

Hallmark of chronic nerve injury

A

Onion bulb formation

23
Q

Sensory in myopathy (+/-)

A

(-)

24
Q

Pain in radiculopathy? (+/-)

A

(+)

25
Q

Proximal weakness

A

Myopathy

26
Q

Distal weakness

A

Neuropathy

27
Q

Elevated CK

Elevated aldolase

A

Myopathy

28
Q

EMG/NCV

A

Electromyography/Nerve Conduction Velocity

29
Q

EMG/NCV waves important in GBS

A

F waves

30
Q

Rain on roof

A

Fibrillations

31
Q

Popcorn popping

A

Positive sharp waves

32
Q

Inc amplitude, long duration, dec recruitment

A

Neuropathy

33
Q

Dec amplitude, short duration, early recruitment

A

Myopathy

34
Q

Picket fence on EMG/NCV

A

Neuropathy

35
Q

CSF findings in GBS

A

Albuminocytologic dissociation

36
Q

What is albuminocytologic dissociation

A

Inc CSF proteins

No inc in WBC

37
Q

Absent or markedly prolonged F responses

A

GBS

38
Q

GBS Tx

A

IVIg (0.4g/kg/d for 5 days) GOLD!
Plasmapheresis
Steroids not indicated

39
Q

MC d/o of NM transmission

A

Myasthenia gravis

40
Q

Bimodal onset of MG

A

20and 30: females

60 and 80: males

41
Q

Pathophy of MG

A

Dec in available AChR at postsynaptic memb
Autoimmune response of AChR Ab (IgG and T cell)
Thymus?

42
Q

T/F: DYR and sensation are preserved in MG

A

Thrue

Chrue

43
Q

5 Dx of MG

A 
Tensilon test
Ice test
Repetitive nerve stimulation
ACh Ab testing
Single fiber EMG
44
Q

AChE inhibitor used in tensilon test

A

Edrophonium
2mg IV
8mg IV

With atropine at bedside

From Flashcardlet (33 decks)

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