Med Review Notes

Question 1

Indication for risperidone in elderly ….

maximum duration ….

Answer 1

Aggression in Alzheimers disease - where there is a risk of harm to pt or others
6weeks

Question 2

Nitrates are used in treatment of….

work by…

Answer 2

angina

vasodilators - reduce venous return which reduces LV work

Question 3

Duration of action of sublingual GTN

Answer 3

20-30 mins

Question 4

advantage and disadvantages of transdermal nitrate preparations

Answer 4

• tolerance may develop

- duration of effect prolonged

Question 5

advantage of isosorbide dinitrate over GTN

Answer 5

stable for longer - suitable for less frequent use

Question 6

activity of isosorbide dinitrate is dependent on what pt factor

Answer 6

productions of the active metabolite isosorbide mononitrate

Question 7

how to maintain effectiveness of transdermal nitrates

Answer 7

reduce blood nitrate levels for 4-12 hours daily or tolerance will develop

Question 8

how to maintain effectiveness of MR isosorbide dinitrate and conventional release isosorbide mononitrate

Answer 8

second dose 8 hours after first - not 12 hours. Or tolerance may develop

Question 9

s/e of nitrates (4)

Answer 9

tachycardia
throbbing headache
postural hypotention
dizziness

Question 10

GTN tabs discarded …. after opening

Answer 10

8 weeks