Megaloblastic Anemia Flashcards
1
Q
Functions of folate
A
Synthesis of thymidylate from uridylate (dUMP to dTMP)
Synthesis of methionine from homocysteine
Synthesis of purines
Histidine catabolism
2
Q
Earliest sign in vit b12 or folate deficiency detected before the onset of anemia
A
Macrocytosis
3
Q
In severe anemia
A
Macrocytosis Marked anisopoikilocytosis Basophilic stippling Howell-jolly bodies Cabot’s ring
4
Q
Megaloblastic anemia-White cells
A
Hypersegmentation-present when more than 5% neutrophils show 5 or more lobes
