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Memorable Psychopharmacology > Memorable Psychopharm > Flashcards

Memorable Psychopharm Flashcards

1
Q

Serotonin effects
SPAROW-tonin effects

A

Sleep
Plt dys
Ab upset
Repro effects
Overdose
Weight gain

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2
Q

Where serotonin is produced

A

Raphe nuclei

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3
Q

Serotonin Syndrome 8

A

Shits
Shivering
Hyperreflexia
Increased temp
Vital sign instability
Encephalopathy
Restlessness
Sweating

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4
Q

Effects of DOPAMINE

A

Drug addiction
Outcomes
Psychosis - they cause positive sx
Attention
Movement - there will be EPS when DA is blocked
Inhibition of Prolactin
Nausea
Energy

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5
Q

Positive sx in schizophrenia due to high DA in

A

mesolimbic path

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6
Q

DA blocks prolactin via

A

tuberoinfundibular path

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6
Q

Negative sx due to low DA in

A

mesocortical path

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7
Q

DA is involved in reward path via the

A

VTA

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8
Q

DA is involved in movement via the

A

nigrostriatal path

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9
Q

effects of NE 6

A

Fear
Focus
Fired up
Fasting
Feedback pain inhibition
Full body response fight or flight

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10
Q

NE is produced in the ____

A

locus ceruleus

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11
Q

___ adrenergic found all over the place

A

Alpha 1

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12
Q

____adrenergic block the SNS

A

Alpha 2

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13
Q

Beta 1 receptors found in the

A

heart

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14
Q

Beta 2 receptors found in the

A

lungs

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15
Q

Adrenergic receptors usually constrict smooth muscles, but ____ receptors relax the bronchioles

A

B2

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16
Q

Acetylcholine receptors located in peripheral organs

A

muscarinic

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17
Q

Ach receptors that are involved in cognition and muscle contraction

A

nicotinic

18
Q

Effects of activating muscarinic receptors (SLUDGEBM)

A

Salivation
Lacrimation
Urination
Diaphoresis
GI motility
Emesis
Bradycardia
Miosis

19
Q

Anticholinergic effects 7

A

blind as a bat - blurry vision

Dry as a bone - dry
eyes/mouth/decreased sweating

Hot as a hare - fever

Stuck on the throne - urinary retention and constipation

Red as a beet - flushing of skin

Heart in the zone - tachycardia

Mad as a hatter - delirium and cognitive impairment

20
Q

where Ach is produced

A

nucleus basalis of Meynert

21
Q

Histamine is involved in 2

A

Sleep and allergies

22
Q

Effects of opioid ARMED Colonialist

A

Analgesia
Resp depression
Miosis
Euphoria
Drowsiness
Constipation

23
Q

NT that serves as Neuron’s off switch = inhibitory

A

GABA

24
Q

2 roles of GABA

A

Sedation and relaxation

25
Q

2 GABAergic drugs

A

Barbiturates
Benzodiazepines

26
Q

NT that serves as Neuron’s on switch = excitatory

A

Glutamate

27
Q

2 receptors glutamate act on

A

NMDA
AMPA

28
Q

drugs that bind NMDA receptors (4)

A

NO
Memory enhancers (dementia)
Dissociative hallucinogens (ketamine and PCP)
Alcohol

29
Q

AMPA receptors are involved in ___

A

seizures propagation

30
Q

effects of oxytocin 4

A

Birth
Lactation
Orgasm
Connection

31
Q

2 roles of orexin

A

Promotes hunger and wakefulness

32
Q

Antidepressant discontinuation syndrome (FINISH sx)

A

Flu-like

Insomnia and disturbed sleep

Nausea

Imbalance such as lightheadedness and vertigo

Sensory disturbances such as tingling and electrical sensations in the head

Hyperarousal including increased energy and anxiety

33
Q

4 receptors antipsychotics hit

A

muscarinic
alpha 1
serotonin
histamine

34
Q

Nerves that carry VOLUNTARY motor signals from brain to muscles travel in bundles known

A

pyramidal tracts

35
Q

Nerves that carry INVOLUNTARY motor signals (help finetune movements making them appear smooth and coordinated) travel outside of the pyramidal tracts known as

A

EXTRAPYRAMIDAL tracts

36
Q

EPS:Involuntary contraction of a muscle group often involving the face or neck

A

acute dystonia

37
Q

2 tx for acute dystonia

A

diphenhydramine/benadryl or benztropine/cogentin

38
Q

EPS: Restlessness or jitteriness; internal sense of anxiety

A

akathisia

39
Q

3 tx for akathisia

A

propranolol, benzo, anticholinergic

40
Q

EPS:grimacing, lip smacking, chewing, tongue flicking, excessive eye blinking

A

tardive dyskinesia

41
Q

Neuroleptic Malignant Syndrome presentation (FEVER)

A

Fever
Encephalopathy
Vital sign instability
Elevated WBC and CPK
Rigidity

42
Q

Serotonin Syndrome presentation

A

diarrhea, hyperreflexia, shivering

43
Q

Mgmt NMS

A

Dantrolene or bromocriptine

Memorable Psychopharmacology (1 decks)

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