Metabolic Pathways Flashcards
What is a Metabolic Pathway?
Metabolism can be defined as all the chemical reactions that occur within the human body. Metabolic pathways involve the BUILDING UP and BREAKING DOWN of molecules
Anabolic Pathways
These REQUIRE ENERGY and involve building up processes
e.g building up of amino acids to form proteins
Catabolic Pathways
These RELEASE ENERGY and involve the breakdown of molecules
e.e breaking down of glue in glycolysis
Are Anabolic and Catabolic pathways reversible?
they have irreversible and reversible steps and alterative routes
Activation Energy
The energy needed to break chemical bonds in the reactant is called the activation energy.
What does a Catalyst do?
-Lowers the activation energy required for a chemical reaction to proceed
-Speeds up the rate of a chemical reaction
-Takes part in the reaction but remains unchanged at the end of it
What does an Enzyme do?
(An enzyme is a biological catalyst)
-Lowers the activation energy required by the reactants to form the transition state
-Speeds up the rate of the reaction
-Made of protein
Enzyme Specificity
An enzyme contains an active site which contains a specific shape. An enzyme only acts on one substrate.
What has a high affinity for active site?
Substrate
What has a low affinity for active site?
Products
What does induced fit ensure?
This ensures that the active site comes into very close contact with the molecules of substrate and increases the chance of the reaction taking place
Induced Fit
This occurs when the active site changes shape to better fit the substrate after the substrate binds
To function efficiently an enzyme requires a suitable?
-Tempteture
-pH
-Substrate concentration
-Enzyme concentration
How does the Substrate concentration effect enzyme activity
As substrate concentration increases, the rate of reaction increases and then the rate of reaction remains constant as the active site are all occupied because of the enzyme concentration is the limiting factor
Metabolic pathways can be controlled by:
-Presence of an enzyme
-Absence of an enzyme
-Key enzymes regulating the rate of reaction within a metabolic pathway