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Micro Test 2 > Micro 1 T2 > Flashcards

Micro 1 T2 Flashcards

1
Q

Corynebacterium Diptheria

A 
Klebs-Loffler bacillus
Gram +
pleomorphic
nasopharynx
usually where no immunization
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2
Q

Corynebacterium Diptheria

Pathogenicity

A

psudomembrane in pharynx at site
toxin diffusion
death usually due to heart damage
fatal 5-10% if untreated

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3
Q

Corynebacterium Diptheria

Cutanious Diptheria

A

“punched out lesions” usually on legs

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4
Q

Corynebacterium Diptheria

Clinical

A

Isolation using Loeffler’s medium
Quarintine
Antibiotic
SHICK TEST (red if susceptible)

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5
Q

Mycobacterium tuberculosis

Koch’s bacillus

A 
Acid-fast
asscociated with poverty
approx 1 million cases in US
highly infectious
respitory infection (usual)
ingestion (occasional)
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6
Q

Mycobacterium tuberculosis
(Koch’s bacillus)
Pathogenicity

A 
cord factor (mycolic acid)
lesions or tubercles
pluericy
vague chest pains 
fatigue
night sweats
afternoon fever
Chronic
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7
Q

Mycobacterium tuberculosis
(Koch’s bacillus)
Clinical

A 
Growth in sputum or lesion is proof of infection
Lowenstein-Jensen medium
X-ray for detection
Tuberculin skin tests
treatment- bedrest, adequate diet
BCG immunization
Chemotherapy: Streptomyocin, isoniazid
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8
Q

Mycobacterium bovis

Bovine Tuberculosis

A

closely related to M.tuberculosis

strain used in B.C.G vaccine

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9
Q

Mycobacterium bovis
Bovine Tuberculosis
Pathogenicity

A

Normally in cattle
Infection for humans from unpasterized milk
Lesions in bone marrow of hip, knee, or vert.
Inhalation=M.tuberculosis

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10
Q

Mycobacterium bovis
Bovine Tuberculosis
Clinical

A

Antibiotics and chemotherapy
Pasteurization of milk
Eliminate all cattle with disease
Montoux test (PPD) if no prior vaccination

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11
Q

Mycobacterium leprae
Leprosy
Hansen’s bacillus

A

Acid-fast, related to M.tuberculosis
first described in 1874
disease of antiquity
Still a problem in parts of the world

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12
Q

Mycobacterium leprae
Leprosy
Hansen’s bacillus
Pathogenicity

A

inhalation of infectious droplets—source of general infection
Incubation Period=2-5 years

Lerpromentous(Cutaneous)
Tubeculoid(anesthetic)

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13
Q 
Mycobacterium leprae
Leprosy
Hansen's bacillus
Pathogenicity
Lerpromentous(Cutaneous)
A

progressive cutaneous lesions
death if untreated
seen in skin scrapings

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14
Q 
Mycobacterium leprae
Leprosy
Hansen's bacillus
Pathogenicity
Tubeculoid(anesthetic)
A

peripheral nerves
severe atrophy
sefl-limiting-frequently
will NOT be seen in skin scrapings

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15
Q

Mycobacterium leprae
Leprosy
Hansen’s bacillus
Clinical

A

Careful disinfecting of contaminated articles
sulfone drugs- usually several years
prohylaxis therapy for all family
will multiply in mouse foot pads and armadillos
grows intracellularly
some people immune
Lepromin skin test

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16
Q

Brucella

4 species

A

B. abortus-cattle
B.suis-swine
B.melitensis-goats
B.Canis-dogs

17
Q

Brucella
Brucellosis
(Undulent fever, Bang’s disease, Malta fever, Mediterranean fever)

A

Gram-negative bacillus
Discovered 1887-Bruce
disease of animals-can be transmitted to man
contract from broken skin, ingestion—-
inhalation=usual

18
Q

Brucella
Brucellosis
(Undulent fever, Bang’s disease, Malta fever, Mediterranean fever)
Pathogenicity

A 
Infection spreads through lymhatic and circulatory to reticuloendothelial system
chronic for some
fatal if not treated
undulant fever
animals may lose their young in utero
19
Q

Brucellosis
(Undulent fever, Bang’s disease, Malta fever, Mediterranean fever)
Clinical

A

Cultivation in blood—also in spinal fluid, pus, or bone marrow
agglutination test for WBC clump
treatment=antibiotics
pasteurization neccesary

20
Q

Yersinia Pestis
Bubonic plague
“Black Death”

A 
small, short, gram (-) rod
primarilly disease of rodents
Cosmopolitan
killed 25% of Western Europe
zoonosis
21
Q

Yersinia Pestis
Bubonic plague
“Black Death”
Pathogenicity”

A

three patterns= 1.bubonic,2.septicema,3.pneumonic
flea bite intiates infection
spreads through lymphatic nodes
hemorrhage give skin black splotches

22
Q

Yersinia Pestis
Bubonic plague
“Black Death”
Clinical

A

Flea control
early treatment with antibiotics
vaccines not effective
immunoflourescence (F.A)=rapid identification of smears

Micro Test 2 (1 decks)

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