Microcirculation and Bulk Flow Flashcards

1
Q

Excess water and solutes that filter out of the capillary are picked up by the ___ and returned to circulation.

A

lymph vessels

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2
Q

An average of ___ L/day of fluid filters out of the capillaries

A

3

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3
Q

Microcirculation lacks a…

A

nerve supply

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4
Q

Microcirculation is located only in…

A

connective tissue

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5
Q

Microcirculation is composed of only what type of tissue?

A

Squamous epithelial tissue (endothelium) with thin basal lamina

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6
Q

Name the two types of capillaries

A

Continuous and fenestrated

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7
Q

Where are continuous capillaries?

A

Blood brain barrier, muscle, nervous tissue

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8
Q

Where are fenestrated capillaries?

A

Kidney and small intestine

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9
Q

Movement across the wall of the capillary and lymphatic vessels is by…

A

diffusion

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10
Q

How do gases move across the wall of the capillary?

A

Directly through the phospholipid bilayer

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11
Q

How do ions and water moves across the wall of the capillary?

A

Through pores or at junctions of cell

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12
Q

List five factors that increase diffusion

A
  1. concentration gradient increases
  2. temperature increases
  3. surface area increases
  4. number of pores or channels increases
  5. distance decreases
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13
Q

Lymph is a ___ pressure, such as ___

A

negative pressure, such as -5 mmHg (lymph sucks)

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14
Q

Movement of water is by…

A

bulk flow

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15
Q

What is bulk flow?

A

The balance between the pushing and pulling forces between the capillary and the interstitial fluid

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16
Q

Hydrostatic pressure is due to…

A

water pressure in the capillary or the interstitial fluid.

17
Q

More volume is ___ pressure due to larger diameter vessel or vasodilation.

A

more

18
Q

Why is more volume more pressure?

A

Due to larger diameter vessel or vasodilation

19
Q

What force of bulk flow is pushing?

A

Hydrostatic pressure

20
Q

The pulling force of bulk flow is called…

A

osmotic pressure or oncotic pressure

21
Q

The capillary has ___ pressure due to albumin.

A

plasma colloidal osmotic pressure

22
Q

Why does the capillary have plasma colloidal osmotic pressure?

A

Due to albumin

23
Q

What causes interstitial fluid osmotic pressure or oncotic pressure?

A

Proteins in the IF, such as collagen and elastin

24
Q

In the kidney, the ___ is the capillary, and the IF is termed ___.

A

the glomerulus is the capillary, and the IF is termed Bowman’s space

25
Q

In the kidney, without pathology, why is the IF oncotic pressure zero in Bowman’s space?

A

There is no protein in the glomerular filtrate

26
Q

What type of capillaries have a filtration coefficient?

A

Very porous capillaries

27
Q

With a filtration coefficient, how do you determine total flow?

A

Multiply filtration coefficient by bulk flow

28
Q

Water moving out of the capillary gets a ___ sign.
Water moving into the capillary gets a ___ sign.

A

Out = plus
In = minus

29
Q

Pc or hydrostatic pressure gets a ___ sign.

A

plus

30
Q

PIF or interstitial fluid hydrostatic pressure gets a ___ sign.

A

minus

31
Q

PIF always pushes back into the capillary and ___ the lymph, so if PIF goes up, lymph flow ___.

A

into the lymph, so if PIF goes up, lymph flow increases

32
Q

PiIF or interstitial fluid colloidal osmotic pressure (oncotic pressure) gets a ___ sign.

A

plus

33
Q

Pip or colloidal osmotic pressure of plasma is due to…

A

albumin

34
Q

Pip or colloidal osmotic pressure of plasma gets a ___ sign.

A

minus

35
Q

Bulk flow=

A

Pc - PIF + PiIF - Pip

36
Q

The positive number of bulk flow is…

A

filtration

37
Q

The negative number of bulk flow is…

A

absorption