Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology 1 > Midterm 2 > Flashcards

Midterm 2 Flashcards

1
Q

Tranquilizer sedative with mild analgesic action

A

Droperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Sedative drugs with no analgesic properties, but it potentiates the effect of analgesics

A

Acepromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which animal species is most sensitive to Xylazine

A

Cattle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Post narcotic excitation is frequently seen when using this inhalational anesthetic

A

Halothane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the physical state of the dispersed phase in the suspension

A

Solid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Examinations conducted according to GLP

A

Preclinical exams: Toxicology, kinetics, residual drug exam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Extracting agent to prepare extract

A

Both (water and alcohol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which ointment is not washable with water

A

Paraffin ointment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Alpha 2 agonist not used in Horses

A

Medetomidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Extravascular administration of this anaesthetic drug causes strong tissue irritation

A

Thiamilal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which ingredient of ointment base belongs to hydrocarbons

A

Hard paraffin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Sedative drug with no analgesic properties

A

Chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Doest not cause serious tissue irritation, so can be given IM

A

Ketamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which vehicle is useful for preparation of eye ointment

A

White vaseline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Increases the Prolactin, not suitable in pseudo pregnant animals

A

Chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which investigation belongs to the clinical phase

A

Field trial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Teratogenicity studies have to be performed at least on

A

2 spp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Sedative that decreased BP, cannot be given to dehydrated animals

A

Acepromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

In case of Fentanyl overdose, the antidote is

A

Naloxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Sedative drug with pronounced antiseptic action

A

Acepromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the formulation type of suspensio terpini

A

Aqueous suspension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Dosage form of the alcoholic extract of medicinal plants

A

Tincture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Extravascular administration of this anaesthetic drug causes strong tissue irritation

A

Metomidate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Which ointment is washable with water

A

Hydrophilic ointment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Which one cannot be an attribute of ointments

A

Dissolves at body temperature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

GSH category

A

Highly toxic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Less soluble liquid active ingredient is dispersed in liquid vehicle

A

Emulsion

28
Q

What is MRL

A

Max. Residual Limit, known as the max. concentration of residue of an applied drug

29
Q

Drinking water stability test

A

0, 6, 12, 24 hours

30
Q

Injection pH

A

Not determined (some say neutral but no exactitudes)

31
Q

Requirements of anaesthesia

A

Muscle relaxant, unconsciousness and analgesia

32
Q

Stability studies of closed package at 25 deg.C

A

60% RH (real time)

0, 3, 6, 9, 12, 18, 24 and 36 months

33
Q

Stability studies of closed package at 40 deg.C

A

75% RH (accelerated)

0, 3, 6 months

34
Q

Time of Stability studies in medicated foods

A

0, 1, 2 and 3 months

35
Q

Time of stability tests in ongoing tests

A

0, 3, 6, 9 and 12 months

36
Q

Opened package time of stability test

A

0, 2, and 4 weeks

37
Q

What is Antipamezone the antidote of

A

Alpha 2 agonists

38
Q

What is a water soluble base

A

Hemicellulose

39
Q

What is the study of pharmacology

A

The effect of the drug

40
Q

What is a water insoluble base

A

Hydrocarbons (paraffin & paraffin) and Waxes

41
Q

What is in an emulsion

A

Two or more liquids that don’t usually mix

eg. Oil in water / Water in oil

42
Q

What is the content of paste

A

Solid 40%
Active substances: anthelminthics, antibiotics, sedatives, probiotics, etc
Vehicle: gel or paste
Application: ointment or oral

43
Q

Which analgesic can we give to pigs

A

Azaperone (IM)
Combinations:
- Ketamine + Xylazine
- Butorphanol + Xylazine

44
Q

What are ointments

A

Homogenous
Don’t dissolve at BT
Don’t contain solid particles

45
Q

Ointment usage

A

Local administration

Systemic effect: high lipophilicity or appropriate vehicle

46
Q

Water soluble ingredients in Ointments

A

Plants & animal polymers:
- agar, gelatine, methylcellulose, starch
Synthetic polymers:
- macrogols, polysorbates

47
Q

Bases for hydrophobic ointments

A

White soft paraffin

Yellow soft paraffin

48
Q

Water emulsifying ointments, capable of O/W emulsion are

A
  • Anionic emulsifying wax
  • Nonionic “ “
  • Cetomacrogol “ ointment
  • Anionic “ “
49
Q

Water emulsifying ointments, capable of W/O emulsion are

A
  • Simple ointment
  • Paraffin ointment
  • Hydrous ointment
50
Q

Coherent formulations

A

Heterogenous:
- ointment, pastes, creams, tablets and suppositories
Colloidal:
- gels

51
Q

Incoherent formulations

A 
Heterogenous:
- powders, emulsion, suspension and granules
Colloidal:
- colloidal solution, stock solution
Homogenous:
- solutions and tinctures
52
Q

Tranquilizer sedatives with no analgesic effects

A

Phenothiazines

53
Q

Tranquilizer sedatives with slight analgesic effects

A

Butyrophenones

54
Q

5 Phenothiazines

A
  1. Chlorpromazine: Eq paradox reaction, IM = tissue irritation
  2. Propionil-promazine: penis prolapse in stalliona
  3. Acepromazine
  4. Thiethylperazine: pronounced antiemetic effect
  5. Promethazine: pronounced anti-H activity
55
Q

3 Butyrophenones

A
  1. Azaperone: IM for swine
  2. Droperidol
  3. Fluanison: in small lab animals
56
Q

What are Alpha-2 agonists and their antidote

A 
Cause sedation, analgesia, muscle relaxant activity
Suspended with Alpha-2 antagonists:
- Atipamezole
- Yohimbine
- Tolazoline
57
Q

Receptorial effects of tranquilizers

A 
Anti alpha 1
Anti dopamine activity
Anti Histamine activity
Anti serotonin activity
Anti muscarine effect
FSH drops
58
Q

Alpha 2 agonists (5)

A 
Xylazine
Detomidine
Romifidine
Medetomidine
Dexmedetomidine
59
Q

What are Benzodiazepines and their antidotes

A

Cause sedations, anxiolytic and muscle relaxant activity
Antidotes:
Flumazenil
Sarmozenile

60
Q

What are Barbiturates

A

Sedation, anxiolytic, muscle relaxant activity and anticonvulsive

61
Q

Long acting barbiturate

A

Phenobarbital

62
Q

Medium acting barbiturates

A

Butobarbital
Amobarbital
Ciklobarbital
Allobarbital

63
Q

Short acting barbiturate

A

Pentobarbital

64
Q

Ultra short acting barbiturates

A 
Thiopental
Thiamilal
Hexobarbital
Venobarbital
Methohexital
65
Q

Injection ph

A

Normal: 7.4

Should be between 5-7

Pharmacology 1 (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions