Misc

Question 1

Which diuretics can cause ototoxicity?

Answer 1

Loop diuretics

Question 2

Name 4 loop diuretics.

Answer 2

Furosemide, bumetanide, ethacrynic acid, torsemide

Question 3

Which diuretic may cause volume expansion and pulmonary edema?

Answer 3

mannitol

Question 4

Which diuretic can cause decreased libido, impotence, and gynecomastia?

Answer 4

spironolactone

Question 5

Where is digoxin metabolized?

Answer 5

Kidneys

Question 6

3 aspects of von Hippel Lindau disease:

Answer 6

1. cerebellar hemangiomas
2. clear cell renal carcinomas
3. pheochromocytomas

Question 7

Where is the VHL gene located?

Answer 7

Ch. 3p

Question 8

What 2 malignancies are associated w/ RB gene mutation?

Answer 8

retinoblastoma and OSTEOSARCOMA

Question 9

Which virus elaborates a protein that inhibits the p53 suppressor gene?

Answer 9

HPV-16 (E6 protein)

Question 10

Whic virus elaborates a protein that inhibits the RB suppressor gene?

Answer 10

HPV-18 (E7 protein)

Question 11

Angiotensin II constricts the _______ arteriole to increase GFR? This results in _______ in filtration fraction.

Answer 11

efferent, no change

Question 12

Prostaglandins dilate the _______ arteriole to increase GFR. This results in _______ in filtration fraction.

Answer 12

afferent, increase