Mitochondria- cell death

Question 1

define necrosis

Answer 1

(uncontrolled cell death). Associated with disease.

Question 2

define apoptosis

Answer 2

(programmed cell death or cell suicide). Apoptosis is an essential part of normal health and development. In an average adult between 50 and 70 billion cells die through apoptosis per day

Question 3

what 5 things shows the importance of apoptosis?

Answer 3

• Embryo development – sculpting tissue
• Immune system – destroying self-reacting immune cells.
• Immune system – destroying virus infected cells.
• Homeostasis – as a counter-balance to cell division and removal of old or damaged cells.
• Cancer – radiotherapy and most chemotherapy drugs work by inducing apoptosis. Many cancer cells have defects in the apoptosis pathways that make them resistant to apoptosis.

Question 4

what are 2 main pathways for triggering apoptosis?

Answer 4

• Receptor mediated (extrinsic pathway)
• Mitochondria mediated (intrinsic pathway)