mitosis and the cell cycle Flashcards

1
Q

what does mitosis produce

A

2 genetically identical daughter cells

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2
Q

what does meiosis produce

A

4 daughter cells with half the number of chromosomes

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3
Q

order of cell cycle

A

interphase
prophase
metaphase
anaphase
telophase
cytokinesis

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4
Q

what happens during prophase

A

chromatin condenses
spindle fibres start to develop
nucleolus disappears
nuclear envelope breaks down

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5
Q

what happens during metaphase

A

chromosomes pulled along spindle apparatus and arranged across equator of the cell

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6
Q

what happens during anaphase

A

centromeres divide in 2
spindle fibres pull chromatids to opposite poles of the cell

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7
Q

what happens during telophase

A

chromosomes return to chromatin state
spindle fibres disintegrate
nuclear envelope + nucleolus reforms

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8
Q

what happens during cytokinesis

A

cytoplasm and cell membrane divides to form 2 daughter celld

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9
Q

what happens during interphase

A

synthesis of DNA
synthesis of protein
synthesis of ATP
growth of cytoplasm and organelles

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10
Q

what happens during binary fission

A

DNA replicates
cell membrane grows and pinches inwards, dividing cytoplasm
new cell wall forms between
produces 2 daughter cells

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11
Q

what is the process of replication of viruses

A

attach to host cell
inject nucleic acid into cell
this instructs host cell to produce viral components, nucleic acid, enzymes and proteins
new viruses are made inside host cell
host cell bursts to release new viruses

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12
Q

what is it called when the host cell bursts

A

lysis

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13
Q

what causes cancer

A

mutation in a gene that controls the cell cycle causing damage to genes leading to the development of a tumour

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14
Q

what can the rate of mitosis be affected by

A

the environment of the cell
growth factors
proto oncogenes
tumour suppressor factors

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15
Q

what can a mutation to a proto oncogene / tumour suppressor factors cause

A

uncontrolled mitosis

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16
Q

what are the features of a malignant tumour

A

very uncontrolled division
less compact
more likely to be life threatening
can be carried by the blood steam or lymphatic system to invade other tissues

17
Q

what are the features of a benign tumour

A

do not spread from point of origin
do not cause cancer
less life threatening

18
Q

three treatments for cancer

A

surgery - removal of tumour
radiotherapy
chemotherapy

19
Q

what is radiotherapy

A

radiation damages DNA and causes cells to kill themselves

20
Q

what is chemotherapy

A

drugs used to treat cancer

21
Q

how does chemotherapy work (2 ways)

A
  • prevents DNA from replicating
  • inhibits the metaphase stage of mitosis by interfering with spindle formation
22
Q

what is the issue with cancer drugs

A

they also disrupt cell cycle of normal cells

23
Q

why does chemotherapy cause hair loss

A

drugs are more effective against rapidly dividing cells - hair cells are rapidly dividing