Module 1 Flashcards
One of the first steps to doing a research study
Review of Literature
Components of the evidence based medicine cycle
ask question search literature appraise evidence integrate data make decision
PICOM
population intervention or exposure comparisons made (control) outcome of interest methodologic (study design)
Dependent variable
Outcome of interest
Independent variable
Intervention or Exposure
Prime requirement of any study; lack of significant bias
Validity
Consistency
Precision
Any 2 articles (or more)
Review
Actual recommendations on management are made
Guidelines
results of trials are combined statistically
meta-analysis
comprehensive, systematic and objective search of the literature based on a research question
overview
local articles database
Herdin
local surgical researches
PJSS
systematic reviews; meta-analysis
Cochrane
Father of Physiology
Claude Bernard
3 Rs campaign
Replacement of animals with non-living models;
Reduction in the use of animals;
Refinement of animal use practices
The WMA Statement on Animal USe in Biomedical Research revised when?
57th WMA General Assembly, Pilanesberg, South Africa, October 2006
The WMA Statement on Animal USe in Biomedical Research adopted when?
41st World Medical Assembly, Hong Kong, September 1989
Most common source of information
books (5-10 years old)
detailed, organized,step by step search for all material available on a topic
Literature Search