Module 2: Hypochromic Anemias Flashcards
Refractory anemia
One which responds poorly to treatment
To determine transferrin saturation you need to measure:
Serum iron and total iron binding capacity
Sideropenic anemia
An anemia caused by biochemical abnormalities in the synthesis of heme in developing red cells - not due to a lack of iron
The most common cause of iron deficiency in infants
Iron poor diet
The plasma iron transport protein is called:
Transferrin
Where is most body iron found?
The red blood cells
Relative anemia may be expected during:
Pregnancy
The protein responsible for temporary storage of iron in body cells
Apoferritin
Where does iron absorption mainly take place?
In the duodenum and jejunum
The major cause of iron deficiency in North America
Iron loss through acute or chronic bleeding
Functions of iron in the body
Formation of heme (in hemoglobin and myoglobin)
Component of cytochromes, catalases and myeloperoxidase
Enzyme activator in some reactions
Normal transferrin saturation
About 30%
Stages of iron deficiency anemia progression
Iron depletion (iron stores are reduced but not absent) Iron deficiency (iron stores are depleted to almost 0) Iron deficiency anemia (Hb is decreased with hypochromia and microcytosis)
Iron depletion
Iron stores are reduced, but not absent
Iron deficiency
Iron stores are depleted to almost zero
