Module 3 Kelsey Chapter 5 Flashcards

1
Q

A lesion associated with secondary syphilis is:

A) condyloma acuminata.
B) condyloma lata.
C) molluscum contagiosum.
D) inguinal bubo.

A

condyloma lata.

Patients with secondary syphilis may present with localized or diffuse mucocutaneous lesions on the palms and soles, mucous patches, and condyloma lata. They may also have generalized lymphadenopathy along with flulike symptoms (low-grade fever, headache, sore throat, malaise, arthralgias).

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2
Q

A 24-year-old patient presents for a routine wellness visit without any complaints. On physical examination, you note a 2-cm, nontender, fluctuant mass at the inferior aspect of the left labia. The most likely diagnosis is:

A) Bartholin’s gland cyst.
B) epidermal inclusion cyst.
C) vestibulitis.
D) vulvar carcinoma.

A

Bartholin’s gland cyst.

The Bartholin’s glands are located at the inferior aspects of the labia (4 o’clock and 8 o’clock). Cysts within these glands are generally unilateral, 1 to 3 cm in size, nontender (unless there is an abscess), and fluctuant.

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3
Q

A sexually active 18-year-old female presents with postcoital spotting, dysuria, and a yellow discharge. On examination, you find her cervix is erythematous and bleeds with contact. The most likely diagnosis is:

A) cervical cancer.
B) chlamydia.
C) primary syphilis.
D) tampon injury.

A

chlamydia.

Symptoms of chlamydia may include postcoital bleeding; intermenstrual bleeding or spotting; symptoms of urinary tract infection—dysuria, frequency; vaginal discharge; and abdominal pain. Physical findings may include mucopurulent endocervical discharge; an edematous, tender cervix with easily induced bleeding; and slight tenderness upon palpation of suprapubic area.

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4
Q

An examination finding that is considered a minimum criterion for empirical treatment of PID in a sexually active young woman presenting with lower abdominal or pelvic pain is:

A) adnexal mass.
B) cervical motion tenderness.
C) fever > 101°F (> 38.4°C).
D) vaginal discharge.

A

cervical motion tenderness.

The minimum criterion for empirical treatment of PID in sexually active young women and other women at risk for STIs with a complaint of pelvic or lower abdominal pain includes the presence of one or more of these three findings on pelvic examination: uterine tenderness, adnexa tenderness, cervical motion tenderness.

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5
Q

A patient with latent syphilis may present with:

A) a maculopapular rash.
B) an indurated painless ulcer.
C) condyloma lata.
D) no signs of infection.

A

no signs of infection.

Patients with latent syphilis show no signs of infection; detection is through serologic testing.

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6
Q

Females exposed to DES in utero are at increased risk for:

A) breast cancer.
B) ovarian cancer.
C) vaginal cancer.
D) vulvar cancer.

A

vaginal cancer.

Females exposed to DES in utero are at increased risk for clear cell carcinoma of the vagina (although rarely; the risk is 1 in 1000).

DES=Diethylstilbestrol (DES) aka estrogen

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7
Q

The most commonly used method of ART is:

A) GIFT.
B) ICSI.
C) IVF.
D) ZIFT.

A

IVF.

IVF is the most commonly used ART, with a success rate of 15% to 20%. IVF comprises a series of complex procedures wherein the oocytes are extracted, fertilized in the laboratory, and then transferred through the cervix into the uterus.

ART=Assisted Reproductive Technology

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8
Q

A 36-year-old is seen in your office on day 18 of her cycle for her routine annual examination. She has no complaints. The pelvic examination reveals a 9-cm firm pelvic mass anterior to the uterus. The most likely diagnosis is:

A) benign cystic teratoma.
B) ectopic pregnancy.
C) endometrioma.
D) follicular cyst.

A

benign cystic teratoma.

Benign cystic teratomas usually measure between 5 and 10 cm in diameter and are composed of well-differentiated tissue from all three germ layers. They are often located anterior to the uterus. Patients are usually asymptomatic but may experience acute pain if the teratoma twists or ruptures.

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9
Q

Which of the following statements concerning ovarian cancer is true?

A) BRCA1 gene mutations increase risk but BRCA2 gene mutations do not.
B) The lifetime risk of ovarian cancer in the general population is 1% to 2%.
C) Ovarian cancer rates are highest among women age 30 to 45 years.
D) Use of oral contraceptives for more than 5 years increases the risk for developing ovarian cancer.

A

The lifetime risk of ovarian cancer in the general population is 1% to 2%.

The lifetime risk for ovarian cancer in the general population is 1% to 2%. The presence of BRCA1 or BRCA2 gene mutations increases this risk. The use of oral CHCs for more than 5 years decreases the risk.

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10
Q

Which of the following treatments for genital warts may be used during pregnancy?

A) Imiquimod cream
B) Podophyllin resin
C) Podofilox gel
D) Trichloroacetic acid

A

Trichloroacetic acid

For the treatment of genital warts in pregnancy, the CDC recommends trichloroacetic or bichloroacetic acid (80% to 90% solution). Imiquimod cream, podophyllin resin, and podofilox gel should not be used during pregnancy.

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11
Q

A 22-year-old female presents with complaint of malodorous vaginal discharge and vulvar itching. On examination, a watery, yellowish-green vaginal discharge is noted, along with vulvar and vaginal erythema. The most likely findings on a wet-mount examination will be:

A) clue cells.
B) lactobacilli.
C) pseudohyphae.
D) trichomonads.

A

trichomonads.

Symptoms of trichomoniasis include copious, malodorous, yellowish-green discharge; vulvar irritation; pruritus; and occasionally dysuria, urgency, frequency of urination, and postcoital and intermenstrual bleeding. Onset of symptoms often occurs after menses. In addition to vaginal discharge, physical examination findings may include erythema and edema of the vagina, a friable cervix, and punctate lesions (strawberry spots) on the surface of the cervix.

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12
Q

Which of the following components of the PLISSIT model would best describe instructing a couple on the use of water-soluble lubrication for dyspareunia caused by vaginal dryness?

A) Permission giving
B) Limited information
C) Specific suggestions
D) Intensive therapy

A

Specific suggestions

The PLISSIT model (P = permission giving, LI = limited information, SS = specific suggestions, IT = intensive therapy) may be used by clinicians who are not sex therapists when counseling patients with sexual dysfunction. Instructing a couple on the use of water-soluble lubrication for dyspareunia caused by vagina dryness constitutes a specific suggestion.

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13
Q

The most common benign neoplasm of the cervix is:

A) Bartholin’s gland cyst.
B) squamous papilloma.
C) pedunculated myoma.
D) polyp.

A

polyp.

Polyps are the most common benign neoplasm of the cervix. They are seen most often in perimenopausal and multigravida women between the ages of 30 and 50 years.

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14
Q

PCOS predisposes women to an increased incidence of:

A) adrenal tumors.
B) endometriosis.
C) endometrial cancer.
D) ovarian cancer.

A

endometrial cancer.

Women with PCOS are at risk for future development of endometrial cancer related to chronic anovulation and unopposed estrogen.

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15
Q

Disorders of pelvic support may be associated with all of the following except:

A) obesity.
B) neuromuscular injury during childbirth.
C) pelvic surgery.
D) frequent UTIs.

A

frequent UTIs.

Disorders of pelvic support result from weakness in supporting structures that include the pelvic diaphragm, ligaments, and fascia. Causes include neuromuscular injury at childbirth, which results in denervation injury of the muscular floor, as well as conditions that cause chronic increase in abdominal pressure—obesity, straining, chronic lung disease (coughing); nerve function altered by diabetes, pelvic surgery, neurologic disorders; and hypoestrogenism.

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16
Q

Leiomyomata arising from tissue within the uterine wall are described as:

A) interstitial.
B) pedunculated.
C) subserosal.
D) submucosal.

A

interstitial.

Leiomyomata can be found in different areas within and around the uterine cavity and surrounding ligaments. Submucosal myomas protrude into the uterine cavity. Subserosal myomas bulge through the outer uterine wall. Intraligamentous myomas are found within the broad ligament. Interstitial (intramural) myomas stay within the uterine wall; they are the most common form of myoma. Pedunculated myomas are found on a thin pedicle or stalk attached to the uterus.

Leiomyomata=fibroid

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17
Q

Another name for a dermoid cyst is:

A) benign cystic teratoma.
B) follicular cyst.
C) hyperplastic endometrioma.
D) Müllerian cyst.

A

benign cystic teratoma.

A dermoid cyst is also known as a benign cystic teratoma. It is the most common ovarian germ cell tumor.

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18
Q

A 16-year-old patient comes to the office because she has never had a menstrual period. She has normal breast development, scant pubic hair, and a blind vaginal pouch with no palpable uterus or ovaries. The most likely diagnosis is:

A) androgen insensitivity/resistance syndrome.
B) Müllerian agenesis.
C) Sheehan’s syndrome.
D) Turner’s syndrome.

A

androgen insensitivity/resistance syndrome.

Androgen insensitivity/resistance syndrome is a genetically transmitted androgen receptor defect. The individual is a genotypic male (46XY) but a phenotypic female or has both female and male characteristics. The individual has normally developed breasts with small nipples and areola, scanty or absent pubic hair, a blind vaginal pouch, and no uterus or ovaries. Testes are present and may be partially descended or intra-abdominal.

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19
Q

Characteristics of Turner’s syndrome include:

A) uterus absent, ovaries absent.
B) uterus absent, ovaries present.
C) uterus present, ovaries absent.
D) uterus present, ovaries present.

A

uterus present, ovaries absent.

Physical characteristics found in persons with Turner’s syndrome include lack of breast development, scant pubic hair, normal uterus and vagina, absent or streak ovaries, short stature, webbed neck, and shield chest with widely spaced nipples. Cardiac and renal anomalies may also be present.

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20
Q

Which of the following contraceptive methods has also been FDA approved for treatment of endometriosis?

A) Combination oral contraceptive pills
B) Levonorgestrel IUS
C) Progestin-only contraceptive pills
D) Subcutaneous 104 DMPA

A

Subcutaneous 104 DMPA

Subcutaneous 104 DMPA is an FDA-approved medication for treatment of endometriosis. Other medical management includes analgesics (NSAIDs are the first choice), GnRH agonists, and danazol to induce regression of endometrial implants; IM DMPA has also been found to be effective.

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21
Q

With which of the following conditions would you expect to see a positive progestin challenge test?

A) Androgen insensitivity syndrome
B) Asherman’s syndrome
C) PCOS
D) Turner’s syndrome

A

PCOS

A positive progestin challenge test indicates the woman who is not having menses has adequate production of estrogen, is able to develop a proliferative endometrium, and has an unobstructed outflow tract.

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22
Q

Primary dysmenorrhea can best be treated with:

A) dopamine agonists.
B) GnRH agonists.
C) prostaglandin inhibitors.
D) tricyclic antidepressants.

A

prostaglandin inhibitors.

Prostaglandin synthetase inhibitors, which are NSAIDs, are the treatment of choice for primary dysmenorrhea. They work best if they are begun at the onset of menses and are continued for 48 to 72 hours. Agents shown to be effective include mefenamic acid, naproxen sodium, ibuprofen, and indomethacin.

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23
Q

Treatment of molluscum contagiosum includes:

A) azithromycin 1 g orally in a single dose.
B) erythromycin base 500 mg orally four times a day for 21 days.
C) trichloroacetic or bichloroacetic acid (80% to 90% solution).
D) cryotherapy with liquid nitrogen.

A

cryotherapy with liquid nitrogen.

Molluscum contagiosum usually resolves spontaneously without scarring. Treatment options include superficial incision, expressing contents with a comedo extractor, curettage with cautery, and cryotherapy with liquid nitrogen (most often used if the patient has multiple lesions).

Molluscum contagiosum: virus with multiple lesions that are dome-shaped, round, and pinkish-purple in color.

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24
Q

Which of the following statements concerning herpes genitalis is true?

A) Suppressive therapy does not reduce viral shedding.
B) Systemic symptoms are uncommon during recurrences.
C) Topical acyclovir is as effective as oral acyclovir for recurrences.
D) Transmission of the virus is unlikely to occur during the prodromal phase.

A

Systemic symptoms are uncommon during recurrences.

A recurrent genital herpes infection usually takes a milder course and does not present with systemic symptoms such as fever, malaise, and headache.

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25
Q

A 66-year-old woman with a history of pruritus presents with an ulceration of the vulva. The most likely diagnosis is:

A) chancroid.
B) secondary trauma.
C) syphilis.
D) vulvar carcinoma.

A

vulvar carcinoma.

The most common signs and symptoms of vulvar carcinoma include pruritus (most common); pain; burning; bleeding lesions that may be darkly or irregularly pigmented, white or red, multifocal or singular, and flat, wartlike, or scaly; erythematous irritated ulceration; and odorous discharge that may be tinged with blood.

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26
Q

The definitive diagnosis of endometriosis is made with:

A) CT scan.
B) laparoscopy.
C) serum CA-125.
D) transvaginal ultrasound.

A

laparoscopy.

Direct visualization with laparoscopy or laparotomy reveals classic implants with endometriosis, classified as Stage I—minimal, Stage II—mild, Stage III—moderate, and Stage IV—severe.

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27
Q

A 22-year-old female has a Pap test report of HSIL. Recommended first steps in follow-up would include:

A) colposcopy.
B) co-testing with Pap and HPV tests in 1 year.
C) reflex HPV test now.
D) repeating just the Pap test in 6 months.

A

colposcopy.

The ASCCP recommendation for follow-up of an HSIL Pap test result in women ages 21 to 24 is colposcopy.

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28
Q

A 24-year-old woman presents with a complaint of a nontender mass in her left breast that does not change with the menstrual cycle. On examination, you note a freely movable, 0.5 cm × 1 cm, firm, rubbery nontender mass. The most likely diagnosis is:

A) fibroadenoma.
B) fibrocystic breast changes.
C) intraductal papilloma.
D) cystosarcoma phyllodes.

A

fibroadenoma.

Fibroadenomas are firm, well-delineated, freely movable, smooth, rubbery, round, typically marble-sized, nontender masses. They usually occur on a unilateral basis.

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29
Q

A 26-year-old woman presents with multiple, painless, umbilicated papules on her mons pubis. The most likely diagnosis is:

A) condyloma acuminata.
B) condyloma lata.
C) lymphogranuloma venereum.
D) molluscum contagiosum.

A

molluscum contagiosum.

Molluscum contagiosum presents with characteristic light-colored papules with umbilicated centers on the trunk, lower extremities, abdomen, inner thigh, or genital area.

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30
Q

PMS is suspected when a woman experiences symptoms only during:

A) ovulation.
B) the luteal phase.
C) the LH surge.
D) the follicular phase.

A

the luteal phase.

PMS is the cyclic occurrence of a group of distressing physical and psychological symptoms in the luteal phase that begins about 5 to 7 days before menses and resolves within about 4 days after onset of menses.

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31
Q

Recommendations for repeat testing after treatment for chlamydia with doxycycline include:

A) test of cure 1 to 2 weeks after treatment if non-adherence is suspected.
B) test of cure 3 to 4 weeks after treatment for all patients.
C) test for possible reinfection 1 month after treatment.
D) test for possible reinfection 3 months after treatment.

A

test for possible reinfection 3 months after treatment.

A test of cure is not recommended for nonpregnant women after treatment for chlamydia with a CDC-recommended regimen. A majority of post-treatment infections are reinfection. The CDC recommends retesting the patient 3 months after treatment ends.

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32
Q

Characteristic “strawberry spots” on the cervix may be seen with:

A) BV.
B) chlamydia.
C) herpes genitalis.
D) trichomoniasis.

A

trichomoniasis.

A classic (although not always present) examination finding with trichomoniasis is punctate red lesions on the cervix often called strawberry spots.

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33
Q

The most common cause of pathologic nipple discharge in perimenopausal women is:

A) breast cancer.
B) fibroadenoma.
C) intraductal papilloma.
D) prolactin-secreting pituitary adenoma.

A

intraductal papilloma.

An intraductal papilloma is a benign lesion of the lactiferous duct found most commonly in the perimenopausal age group, 35–50 years old. It is the most common cause of pathologic nipple discharge.

34
Q

All of the following are risk factors for cancer of the vulva except:

A) cigarette smoking.
B) high-risk type HPV infection.
C) lichen sclerosis.
D) multiparity.

A

multiparity.

Risk factors for vulvar cancer included high-risk type HPV infection, lichen sclerosis, and cigarette smoking.

35
Q

A patient tells you that she has had noticeable reduction in sexual interest and arousal. Which of the following criteria must be met for these symptoms to meet the DSM-5 criteria for sexual dysfunction?

A) She must experience the symptoms 100% of the time.
B) The symptoms must have been present for at least 1 year.
C) She must also have a decrease in orgasms and/or pain with sex.
D) The symptoms must cause her significant distress.

A

The symptoms must cause her significant distress.

The DSM-5 criteria for the diagnosis of sexual dysfunction include sex-related symptoms that occur at least 75% of the time for at least 6 months and cause significant distress for the individual.

36
Q

Which of the following is considered to be a risk factor for nonpuerperal mastitis?

A) Cigarette smoking
B) Dense breast tissue
C) Fibrocystic breast condition
D) Heavy alcohol use

A

Cigarette smoking

Cigarette smoking and nipple piercing are considered to be risk factors for nonpuerperal mastitis.

nonpuerperal=non-lactating

37
Q

A 58-year-old woman complains that she feels as if she is “sitting on a ball.” She has significant constipation and rectal pressure. On examination, you will most likely find a:

A) cystocele.
B) hemorrhoid.
C) rectocele.
D) urethrocele.

A

rectocele.

A rectocele typically presents as a bulging or herniation of the anterior rectal wall and posterior vaginal wall into the opening of the vagina. Constipation, rectal pressure, and a sensation of “sitting on a ball” are symptoms that may occur with a significant rectocele.

38
Q

A 24-year-old nulliparous female with occasional spontaneous, bilateral milky nipple discharge has no other significant breast findings. She has regular menses and a negative pregnancy test. She takes no medications and denies use of illicit drugs. Her prolactin and TSH levels are normal. An appropriate next step in her management would be:

A) advise a repeat prolactin level in 1 year.
B) order a breast ultrasound.
C) order an MRI or CT scan of the pituitary gland.
D) start her on a low-dose dopamine agonist.

A

advise a repeat prolactin level in 1 year.

The woman with galactorrhea who is having regular menses and has normal prolactin and TSH levels may be followed with yearly prolactin levels.

39
Q

Typical characteristics of vulvodynia include:

A) constant vulvar burning and discomfort.
B) inflammation of the vestibular glands.
C) thickened plaques on the vulva.
D) vulvovaginal edema and erythema.

A

constant vulvar burning and discomfort.

Vulvodynia is defined as chronic vulvar discomfort, often described as burning pain, occurring in the absence of relevant physical findings or a specific clinically identifiable neurologic disorder. Symptoms may be generalized, involving the mons pubis, labia majora, labia minora, and perineum, or they may be localized (vestibulodynia) to the vestibule and clitoris.

40
Q

Primary syphilis may be suspected when the patient presents with:

A) a maculopapular rash.
B) an indurated, painless ulcer on the cervix.
C) enlarged, tender inguinal lymph nodes.
D) tender vesicles and papules on the vulva.

A

an indurated, painless ulcer on the cervix.

Primary syphilis should be suspected if a person presents with a painless, ulcerated lesion with raised border; indurated base; and rolled edges on the vulva, vagina, cervix, penis, or other site of potential entry of the syphilis organism. The primary syphilis lesion spontaneously disappears in 1 to 6 weeks.

41
Q

The gonads should be removed after puberty in a person with androgen insensitivity/resistance syndrome to prevent:

A) endometrial hyperplasia.
B) gonadal malignancies.
C) increased risk for breast cancer.
D) psychological trauma.

A

gonadal malignancies.

Once full development is attained (after puberty) in a person with androgen insensitivity syndrome, gonads should be removed at about age 16 to 18 years to reduce the risk of malignant transformation of the gonads (5%). Incidence of malignancy is rare before puberty.

42
Q

Which treatment for chlamydia should not be used in pregnancy because it may lead to the discoloration of teeth in children?

A) Ciprofloxacin
B) Doxycycline
C) Penicillin
D) Trimethoprim

A

Doxycycline

Doxycycline should not be used in pregnancy because it may cause discoloration of teeth in children.

43
Q

Turner’s syndrome can be suspected when the patient has primary amenorrhea and:

A) a blind vaginal pouch with an imperforate hymen.
B) low IQ and visual disturbances.
C) normal breast development but lack of pubic and axillary hair growth.
D) short stature and a webbed neck.

A

short stature and a webbed neck.

Individuals with Turner’s syndrome phenotypically present with short stature, a webbed neck, a shield chest with widely spaced nipples, increased carrying angle of the elbow, an arched palate, a low neck hairline, short fourth metacarpal bones, disproportionately short legs, swollen hands and feet, lack of breast development, and scant pubic hair.

44
Q

A 16-year-old female has not yet begun menstruating but does have pubic hair. She is best described as having:

A) Asherman’s syndrome.
B) oligomenorrhea.
C) primary amenorrhea.
D) secondary amenorrhea.

A

primary amenorrhea.

Primary amenorrhea is characterized by no menstruation by age 14 in the absence of secondary sex characteristics or by age 16 regardless of development of secondary sex characteristics.

45
Q

A 34-year-old female has a normal Pap test with a positive HPV test. Recommended first steps in follow-up would include:

A) colposcopy within the next 6 months.
B) HPV typing test for HPV 16 and 18 now.
C) repeat HPV test alone in 1 year.
D) repeat Pap and HPV tests in 3 years.

A

HPV typing test for HPV 16 and 18 now.

The ASCCP provides two acceptable follow-up strategies for a 34-year-old female who has a normal Pap test with positive HPV test. One strategy is to obtain an HPV typing test for HPV types 16 and 18; if this test positive for HPV 16 or 18, perform colposcopy. Another strategy is to repeat co-testing in 12 months; if either the HPV test is positive or the Pap test shows ASC-US or a higher grade, perform colposcopy. Normal findings for either strategy should be followed with co-testing in 3 years.

46
Q

Trichomoniasis is best treated with:

A) oral fluconazole.
B) oral metronidazole.
C) topical clindamycin cream.
D) topical metronidazole cream.

A

oral metronidazole.

For the treatment of trichomoniasis, the CDC recommends metronidazole 2 g orally in a single dose.

47
Q

A risk factor for endometrial cancer is:

A) DES exposure.
B) early menopause.
C) obesity.
D) multiparity.

A

obesity.

Risk factors for endometrial carcinoma include diabetes, obesity, hypertension, family history, early menarche, late menopause, unopposed estrogen therapy, oligo-ovulation, anovulation, and estrogen-secreting tumors (granulosa cell).

48
Q

The most common presenting symptom of vulvar cancer is:

A) bleeding.
B) pruritus.
C) vaginal discharge.
D) vaginal odor.

A

pruritus.

Symptoms associated with vulvar cancer include vulvar pruritus (most common), pain, burning, bleeding, odorous discharge that may be tinged with blood, and lesions.

49
Q

A patient-applied treatment for genital warts is:

A) bichloroacetic acid.
B) clindamycin cream.
C) imiquimod.
D) podophyllin resin.

A

imiquimod.

Patient-applied treatments for genital warts include imiquimod cream, podofilox gel or solution, and sinecatechins ointment.

50
Q

The ovulation prediction urine test:

A) detects the LH surge.
B) detects an increase in progesterone.
C) predicts fertility level.
D) predicts ovulation within 12 hours.

A

detects the LH surge.

The ovulation prediction urine test detects the LH surge and predicts ovulation within 24 to 36 hours.

51
Q

Which of the following best describes the mechanism of action of tranexamic acid in the treatment of heavy menstrual bleeding?

A) Acts as an antifibrinolytic to block lysis of fibrin clots
B) Causes rapid growth of the endometrium to control an acute, heavy bleeding episode
C) Increases the ratio of vasoconstricting prostaglandins to vasodilating prostaglandins
D) Suppresses endometrial proliferation to manage chronic heavy menstrual bleeding

A

Acts as an antifibrinolytic to block lysis of fibrin clots

Tranexamic acid is effective in blocking lysis of fibrin clots and, when taken up to the first 5 days of menses, reduces heavy menstrual bleeding in women who have increased endometrial plasminogen activity.

52
Q

Vaginal cancer is most commonly found in which part of the vagina?

A) The hymenal ring
B) Midway of the vagina
C) The posterior fourchette
D) The upper one-third of the vagina

A

The upper one-third of the vagina

The most common site of vaginal carcinoma is the upper one-third of the vagina.

53
Q

The most lethal gynecologic malignancy is:

A) cervical carcinoma.
B) choriocarcinoma.
C) endometrial carcinoma.
D) ovarian carcinoma.

A

ovarian carcinoma.

The mortality rate for ovarian carcinoma exceeds those for all other genital tract malignancies.

54
Q

The CDC recommendation for follow-up of a female treated for PID with a recommended outpatient regimen is:

A) advise the patient to return if pain and/or fever persists more than 5 days.
B) reexamine the patient within 72 hours after initiation of treatment.
C) retest for chlamydia and gonorrhea in 2 weeks.
D) see the patient in 1 week to administer a second dose of ceftriaxone IM.

A

reexamine the patient within 72 hours after initiation of treatment.

After treatment for PID, follow-up and reexamination within 72 hours post-treatment are recommended. If the patient is not significantly improved, review the diagnosis and treatment; the patient may need hospitalization.

55
Q

A 58-year-old woman complains of severe vulvar pruritus. On examination of her vulva, you note thinning of the epidermis and loss of pigmentation, as well as maculopapular lesions. You suspect the diagnosis may be:

A) lichen sclerosus.
B) local allergic reaction.
C) lichen simplex chronicus.
D) vulvodynia.

A

lichen sclerosus.

Lichen sclerosus is a chronic, progressive inflammatory skin condition primarily affecting the perineal and perianal areas. Symptoms include pruritus, dysuria, and dyspareunia. Physical examination findings include maculopapular lesions and plaques; loss of pigmentation; markedly thin, white epidermis; loss of vulvar architecture with obliteration of the clitoris; and introital stenosis. There is symmetry in the distribution of skin changes extending around the anal region (figure of eight).

56
Q

Adenomyosis can be suspected when a woman has a(n):

A) boggy, tender uterus.
B) enlarged, irregularly shaped uterus.
C) fixed retroverted uterus.
D) prolapsed uterus.

A

boggy, tender uterus.

Physical findings with adenomyosis include a boggy, tender uterus and diffuse, globular enlargement (may be 8 to 10 weeks’ gestation size) and potentially evidence of anemia.

57
Q

An effective treatment for the symptomatic relief of herpes genitalis is:

A) ceftriaxone.
B) famciclovir.
C) silver nitrate.
D) tetracycline.

A

famciclovir.

Acyclovir, famciclovir, and valacyclovir are systemic antiviral drugs that partially control the symptoms of herpes genitalis. These medications do not eradicate latent virus or affect the risk, recurrence, frequency, or severity of symptoms once the drug is discontinued; suppressive therapy may reduce viral shedding.

58
Q

Risk factors for ovarian cancer include:

A) diabetes.
B) late menopause.
C) history of HPV.
D) oral contraceptive pill use for more than 5 years.

A

late menopause.

Risk factors for ovarian carcinoma include low parity; early menarche; late menopause; and history of breast, colon, or endometrial cancer.

59
Q

An indicator of loss of lactobacilli in the vagina is:

A) elevated pH.
B) increased WBCs on wet mount.
C) malodorous vaginal discharge.
D) vaginal itching.

A

elevated pH.

Loss of lactobacilli (hydrogen peroxide–producing strains) in the vagina results in an elevated pH. An elevated pH may predispose a woman to BV.

60
Q

A complication of PID is:

A) adenomyosis.
B) endometriosis.
C) infertility.
D) irritable bowel syndrome.

A

infertility.

Approximately 25% of cases of PID result in infertility, ectopic pregnancy, or chronic pelvic pain.

61
Q

The pain of primary dysmenorrhea is:

A) always associated with pathology such as endometriosis.
B) colicky, spasmodic, and sometimes radiating up the back to the shoulders.
C) colicky, spasmodic, and sometimes radiating to the thighs and low back.
D) a dull ache associated with underlying pathology.

A

colicky, spasmodic, and sometimes radiating to the thighs and low back.

Primary dysmenorrhea is characterized by pain that begins shortly before the onset of menses and usually lasts no longer than 2 days. The pain is described as colicky, crampy, and spasmodic in the lower abdomen, but sometimes radiates to the lower back and thighs. There is no associated underlying pathology.

62
Q

The test/procedure used in an infertility workup to help determine ovarian reserve is:

A) an AMH level.
B) basal body temperature charting.
C) FSH and LH levels.
D) hysterosalpinogram.

A

an AMH level.

The test commonly used in an infertility workup to determine a woman’s ovarian reserve is an AMH level.

63
Q

Persistent vague abdominal pain or discomfort in a 65-year-old woman may be an early sign of:

A) choriocarcinoma.
B) benign cystic teratoma.
C) endometrial cancer.
D) ovarian cancer.

A

ovarian cancer.

Early signs of ovarian carcinoma include abdominal discomfort or pain, pressure sensation on the bladder or rectum, pelvic fullness or bloating, and vague GI symptoms.

64
Q

Initial management for a 30-year-old woman whose brother had breast cancer should be to:

A) discuss having a risk-reducing bilateral mastectomy.
B) discuss starting her on a selective estrogen receptor modulator.
C) encourage her to have her son tested for BRCA1/BRCA2 mutation.
D) refer her for genetic counseling and possible genetic testing.

A

refer her for genetic counseling and possible genetic testing.

Having a brother with breast cancer places a woman at high risk for hereditary breast and ovarian cancer syndrome. Genetic counseling and genetic testing may guide the discussion regarding additional or more frequent screening and risk-reducing surgeries.

65
Q

Potential causes of galactorrhea include all of the following except:

A) heavy tobacco use.
B) hypothyroidism.
C) opiate use.
D) pituitary adenoma.

A

heavy tobacco use.

Potential causes of galactorrhea include hypothyroidism/hyperthyroidism, use of some medications, use of opiates or cannabis, excessive breast stimulation, and pituitary adenoma.

66
Q

The most common presenting symptom of cervical cancer is:

A) dyspareunia.
B) lower abdominal pain.
C) irregular bleeding.
D) yellow vaginal discharge.

A

irregular bleeding.

Early in the disease process, women with cervical carcinoma may be asymptomatic. The most common presenting symptom of advanced cervical cancer is irregular, painless bleeding or odorous bloody or purulent discharge. Late symptoms include pelvic or epigastric pain and urinary or rectal symptoms.

67
Q

The term for the anatomic abnormality in which a male has a tight foreskin that cannot be retracted is:

A) hypospadias.
B) Peyronie’s disease.
C) phimosis.
D) varicocele.

A

phimosis.

The term for the anatomic abnormality in which a male has a tight foreskin that cannot be retracted is phimosis. Phimosis may be congenital or the result of recurrent infections of the glans penis and prepuce, and may contribute to male infertility.

68
Q

A positive “whiff” or amine test is suggestive of:

A) atrophic vaginitis.
B) BV.
C) chronic lichen sclerosus.
D) recurrent candidiasis.

A

BV.

A positive “whiff” test is the fishy odor that may be found when 10% KOH is added to a vaginal discharge sample of a patient with BV. The whiff test is part of Amsel’s criteria for diagnosing BV, along with vaginal pH ≥ 4.5, clue cells on saline wet mount, and homogeneous white discharge coating the vaginal wall.

69
Q

Which of the following medications is most likely to cause a metallic taste?

A) Acyclovir
B) Azithromycin
C) Fluconazole
D) Metronidazole

A

Metronidazole

Side effects of metronidazole include metallic taste, nausea, headache, dry mouth, and dark-colored urine.

70
Q

The most common cause of chronic pelvic pain in reproductive-age women is:

A) adenomyosis.
B) endometriosis.
C) pelvic inflammatory infection.
D) uterine fibroids.

A

endometriosis.

Approximately 7% to 10% of premenopausal women are affected by endometriosis; it is the most common cause of chronic pelvic pain.

71
Q

Hirsutism is most commonly seen with:

A) androgen insensitivity syndrome.
B) Asherman’s syndrome.
C) PCOS.
D) Turner’s syndrome.

A

PCOS.

Physical findings related to androgen excess with PCOS may include acne, hirsutism, male pattern baldness, deepening of voice, enlargement of clitoris.

72
Q

TSS should be suspected in a woman presenting with sudden-onset fever, flulike symptoms, recent tampon use, and:

A) dysuria.
B) heavy vaginal bleeding.
C) pale conjunctiva and vaginal walls.
D) macular rash on the face and trunk.

A

macular rash on the face and trunk.

TSS is characterized by sudden-onset fever of 102°F or greater and a diffuse macular sunburnlike rash over the face, trunk, and extremities that desquamates 1 to 2 weeks after onset.

73
Q

A 26-year-old female has a Pap test report of ASC-US. This is her first abnormal Pap test. Recommended first steps in follow-up would include:

A) colposcopy within the next 6 months.
B) co-testing with Pap and HPV tests in 1 year.
C) reflex HPV test now.
D) repeat Pap test alone in 3 years.

A

reflex HPV test now.

The ASCCP-preferred follow-up of a 26-year-old female with a Pap test report of ASC-US and no previous abnormal Pap test is to obtain a reflex HPV test. If it is negative, repeat the Pap test in 3 years; if it is positive, perform colposcopy. ASCCP indicates it is also acceptable to repeat the Pap test in 12 months.

74
Q

Mutations in BRCA1 and/or BRCA2 genes are responsible for approximately what percentage of female breast cancers?

A) Less than 5%
B) 5% to 10%
C) 15% to 20%
D) More than 20%

A

5% to 10%

Mutations in BRCA1 and/or BRCA2 genes are responsible for approximately 5% to 10% of female breast cancers.

75
Q

During a vaginal examination, you observe bulging of the anterior wall when you ask the patient to bear down. This is most likely a:

A) congenital abnormality.
B) cystocele.
C) rectocele.
D) uterine prolapse.

A

cystocele.

A cystocele involves the herniation of the bladder into the vaginal lumen.

76
Q

The most common chromosomal abnormality in spontaneously aborted fetuses is:

A) Fitz-Hugh-Curtis syndrome.
B) fragile X syndrome.
C) Müllerian duct abnormalities.
D) Turner’s syndrome.

A

Turner’s syndrome.

Turner’s syndrome (45X) is the most common chromosomal abnormality found on spontaneous abortuses.

77
Q

A 22-year-old patient experiences 6 months of amenorrhea. Laboratory test results include normal prolactin and TSH and negative pregnancy test. The next action will be to:

A) administer a progestin challenge test.
B) measure testosterone.
C) order a hysterosalpingogram.
D) order an MRI or CT scan of pituitary gland.

A

administer a progestin challenge test.

To evaluate an amenorrheic patient, obtain a pregnancy test, serum prolactin level, and TSH test. If all these tests are negative or normal, evaluate the availability of estrogen with a progestin challenge test. Provide oral progestin each day for 10 to 14 days, and then wait for bleeding, which should occur within 7 to 14 days. A positive progestin challenge test indicates adequate estrogen production and stimulation as well as no problem with outflow tract.

78
Q

Which of the following is the most accurate method to predict the occurrence of ovulation?

A) Huhner’s test
B) Evaluation of cervical mucus
C) LH surge test
D) Basal body temperature

A

LH surge test

Ovulation prediction tests detect LH in the urine. A surge of LH precedes ovulation. LH can be detected in the urine a few hours after the surge and within 24 to 26 hours of ovulation.

79
Q

Your examination of a female patient indicates that she has external genital warts. You will want to explain to her that:

A) her partner needs a blood test to see if he has subclinical infection.
B) she should have Pap tests every 6 months.
C) there is no therapy that will eliminate the HPV virus.
D) you cannot start treatment until you have her Pap test results.

A

there is no therapy that will eliminate the HPV virus.

The goal of treatment for genital warts is to eliminate visible lesions; however, no therapy can completely eliminate the HPV virus.

80
Q

The most common presenting symptom of leiomyomata uteri (fibroids) is:

A) heavy or prolonged menses.
B) GI symptoms.
C) infertility.
D) urinary frequency.

A

heavy or prolonged menses.

Patients with leiomyomata uteri (fibroids) are usually asymptomatic. If they do have symptoms, heavy or prolonged menstrual bleeding is the most common presentation.