Module 4 Kelsey Chapter 7 Flashcards

1
Q

A patient has reached week 39 of her pregnancy. On abdominal exam, you measure a fundal height of 42 cm. Leopold’s maneuvers provide you with an EFW of 4200 g. What factors would help to ease your mind about the fetal size?

A) The patient has wide hips and will have no problem with a big baby.
B) The patient is 5 ft 10 in. with an anthropoid pelvis and her husband is 6 ft 4 in.
C) The patient is totally unconcerned and knows this baby will fit.
D) The fetus is not yet engaged, so the height is greater than expected.

A

B) The patient is 5 ft 10 in. with an anthropoid pelvis and her husband is 6 ft 4 in.

The patient’s anthropoid pelvis shape favors a posterior position of the fetus and is adequate for a vaginal birth of a large infant.

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2
Q

Symmetric growth restriction is more likely than asymmetric growth restriction to:

A) be related to multiple gestation.
B) become apparent first in late pregnancy.
C) occur as a result of maternal medical illness.
D) result from maternal cigarette smoking.

A

D) result from maternal cigarette smoking.

Symmetric growth restriction is associated with maternal use of drugs such as tobacco, alcohol, Dilantin (phenytoin), cocaine, and heroin.

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3
Q

A patient returns for the reading of the PPD injection that was placed during the first prenatal visit. You read the result as 10 mm of induration. The patient is American-born and healthy, and has no known history of contact with the disease. How do you interpret this result?

A) It is positive and the patient needs referral to an infectious disease specialist.
B) It is unclear and the patient should have a chest radiograph to be certain.
C) It is positive and you should give the patient a prescription for INH.
D) It is negative because the patient has no high-risk characteristics for the disease.

A

D) It is negative because the patient has no high-risk characteristics for the disease.

PPD test interpretation is based on risk factors:
* Induration of 5 mm is positive for very-high-risk individuals—HIV positive, with abnormal chest radiograph, recent contact with active case.
* Induration of 10 mm is positive for high-risk individuals— foreign born, HIV negative, IV drug user, low-income populations, associated medical problems.
* Induration of 15 mm is positive for patients with none of these risks.

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4
Q

Which of the following is considered a severe feature of preeclampsia?

A) Abdominal pain
B) Blood pressure of 140/90 mm Hg
C) Light sensitivity
D) Thrombocytopenia

A

D) Thrombocytopenia

Severe features of preeclampsia include thrombocytopenia, renal insufficiency, impaired liver function, pulmonary edema, and cerebral or visual symptoms.

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5
Q

Loss of a fetus in the second trimester is most frequently related to:

A) hydatidiform mole.
B) inevitable abortion.
C) ectopic pregnancy.
D) incompetent cervix.

A

D) incompetent cervix.

Second-trimester fetal loss is most likely due to an incompetent cervix. The other stated causes of fetal loss—hydatidiform mole, inevitable abortion, and ectopic pregnancy—are related to first-trimester loss.

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6
Q

Preventive strategies against toxoplasmosis infection include:

A) fully cooking meat to at least 98.6°F.
B) avoiding pasteurized milk and cheeses.
C) avoiding handling kitty litter.
D) fully cooking poultry to 72.5°F.

A

C) avoiding handling kitty litter.

Preventive strategies against toxoplasmosis infection include the following:
* Fully cook meat to at least 145°F (63°C) and poultry to 160°F (71°C).
* Do not drink unpasteurized milk or eat unpasteurized cheese.
* Avoid handling and/or changing kitty litter.
* Avoid drinking untreated water.
* Perform good handwashing following gardening or wear gloves while gardening because soil might be contaminated with cat feces.

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7
Q

Which of the following is a risk factor for hypertensive disorders of pregnancy?

A) Adolescence
B) Multiparity
C) Singleton pregnancy
D) Thyroid disorder

A

A) Adolescence

The following are risk factors for hypertensive disorders of pregnancy: nulliparity, adolescent or advanced maternal age (> 35 years), multiple gestation, family history of preeclampsia or eclampsia, obesity and insulin resistance, chronic hypertension, limited exposure to father of baby’s sperm (new partner), donor insemination, and antiphospholipid antibody syndrome and thrombophilia.

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8
Q

Which of the following is associated with the most severe neonatal outcome?

A) Impetigo
B) Primary herpes simplex virus
C) Pruritis gravidarum
D) PUPPP

A

B) Primary herpes simplex virus

A primary infection with HSV-2 during pregnancy is associated with preterm birth, low birth weight, and neonatal sequelae including local or disseminated infection and encephalopathy.

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9
Q

An elevated maternal AFP result is associated with which of the following?

A) Down syndrome
B) Neural tube defect
C) An autosomal recessive gene
D) X-linked recessive inheritance

A

B) Neural tube defect

An elevated maternal serum alpha-fetoprotein (AFP) is associated with neural tube defects, multiple gestation, and placental abruption.

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10
Q

Infants born to a pregnant person infected with the Zika virus may have:

A) microcephaly.
B) rebound hypoglycemia.
C) hydrocephaly.
D) vesicular lesions.

A

A) microcephaly.

Infants born to a pregnant person infected with Zika may have microcephaly and severe fetal brain damage.

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11
Q

A pregnant patient at 34 weeks’ gestation tells you that she noticed a small amount of blood on her underwear this morning about an hour after having sexual intercourse. She is not having any pain or contractions. Your initial differential diagnosis for this patient would include:

A) cervicitis.
B) incompetent cervix.
C) placental abruption.
D) premature rupture of membranes.

A

A) cervicitis.

Painless bleeding after sexual intercourse at 34 weeks’ gestation may be due to irritation of the cervix from cervicitis. Placental abruption is usually associated with painful bleeding, whereas premature rupture of membranes is typically characterized by loss of fluid.

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12
Q

In the management of anemia following placental abruption, which of the following is the most appropriate treatment strategy?

A) Administration of anticoagulant
B) Replacement of platelets
C) Restoration of volume and blood cells
D) Transfusion of iron

A

C) Restoration of volume and blood cells

Massive hemorrhage requires restoration of volume and cells to maintain perfusion of vital organs.

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13
Q

A pregnant nurse who had previously received the varicella vaccine works at a nursing home caring for older adults. The nurse was exposed to one of the nursing home residents who had shingles. What next steps should this pregnant nurse take?

A) Obtain an obstetric ultrasound as soon as possible.
B) Ask the provider to be swabbed for varicella.
C) Get a varicella vaccine within 72 hours of exposure.
D) Use universal precautions only since shingles poses little risk to the pregnant patient or baby.

A

D) Use universal precautions only since shingles poses little risk to the pregnant patient or baby.

There is no reason to be alarmed given that shingles poses little risk to the pregnant patient or baby.

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14
Q

Risks to the fetus in a post-term pregnancy are related to all of the following except:

A) fetal macrosomia.
B) meconium aspiration.
C) polyhydramnios.
D) uteroplacental insufficiency.

A

C) polyhydramnios.

Post-term pregnancy is typically associated with decreased amniotic fluid, rather than an excess of such fluid.

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15
Q

A woman receiving the varicella vaccine should wait how many weeks before attempting pregnancy?

A) There is no waiting period.
B) 1 week
C) 4 weeks
D) 12 weeks

A

C) 4 weeks

Varicella vaccination is recommended for all susceptible reproductive-age women prior to conception (at least 4 weeks before attempting pregnancy) or postpartum.

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16
Q

Correct information concerning pregnancies with first-trimester bleeding includes which of the following?

A) Approximately 10% of women have some bleeding in the first trimester.
B) Bleeding that occurs between 10 and 12 weeks is often caused by implantation.
C) Cervical incompetence is a common cause of first-trimester bleeding.
D) Approximately 90% of pregnancies in which FHT are heard will continue to term after early bleeding.

A

D) Approximately 90% of pregnancies in which FHT are heard will continue to term after early bleeding.

Approximately 90% of pregnancies with bleeding will continue to term after FHTs are observed. Other information to discuss with the patient includes the following: 40% of women have some bleeding in the first trimester, and 80% of spontaneous abortions occur in the first 12 weeks of pregnancy.

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17
Q

A pregnant 28-year-old woman who is a G1P0 presents at her first antenatal visit at 12 weeks’ gestation with a variable reddish brown rash on her torso, hands, and feet. The rash does not itch. The patient reports fatigue and a recent sore throat. Which of the following laboratory tests may be the most helpful in determining a diagnosis?

A) CBC
B) Quantiferon Gold
C) RPR
D) Serum bile acid

A

C) RPR

An RPR test is part of the standard initial antepartum visit lab set and will confirm a suspected diagnosis of secondary syphilis that aligns with this presentation

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18
Q

The fundal height for a pregnant patient at 20 weeks’ gestation was 1 cm below the umbilicus. At today’s 24-week visit, fundal height is at the umbilicus. The patient is feeling regular fetal movement, and the fetal heart rate is 140 bpm. The most appropriate management for this patient is:

A) ordering a biophysical profile.
B) ordering an ultrasound.
C) performing a nonstress test at this visit.
D) scheduling the next visit for 4 weeks from today.

A

B) ordering an ultrasound.

Ordering an ultrasound is the most appropriate management of the patient to evaluate fetal size and gestation. The patient is too early in gestation for a biophysical profile and a nonstress test. Waiting 4 weeks for an evaluation is too long to wait—the patient needs to be evaluated much sooner.

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19
Q

If a pregnant person with HIV and an undetectable viral load receives antiretroviral therapy during the pregnancy and intrapartum, the rate of transmission to the neonate is:

A) less than 1%.
B) between 5% and 15%.
C) between 15% and 25%.
D) more than 80%.

A

A) less than 1%.

2008 data from the United Kingdom and Ireland showed that pregnant women receiving ART had transmission rates of about 1%.

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20
Q

A woman receiving the rubella vaccine should wait how many weeks before attempting pregnancy?

A) There is no waiting period.
B) 1 week
C) 4 weeks
D) 12 weeks

A

C) 4 weeks

Although there are no documented cases of CRS from vaccine, the recommendation is to wait at least 4 weeks prior to attempting a pregnancy following rubella vaccination. The vaccine may be given to mothers postpartum and while breastfeeding.

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21
Q

Iron-deficiency anemia in the second trimester is most commonly due to:

A) blood volume expansion.
B) degradation of erythrocytes.
C) folate deficiency.
D) poor nutrition.

A

A) blood volume expansion.

Iron-deficiency anemia in the second trimester is most commonly a consequence of expansion of blood volume with inadequate expansion of maternal hemoglobin mass.

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22
Q

When IV access has not been established in the intrapartum setting and the need for immediate treatment related to preeclampsia exists, which of the following is the most appropriate therapy?

A) Hydralazine
B) Labetalol
C) Nifedipine
D) Nitroglycerine

A

C) Nifedipine

immediate-release nifedipine is most appropriate where IV access has not been established.

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23
Q

Which of the following is the most appropriate strategy for antepartum management of preeclampsia?

A) Fluid restriction
B) Increased physical activity
C) Referral to a registered dietician
D) Weekly fetal movement assessment

A

C) Referral to a registered dietician

Antepartum management may include dietary assessment, adequate hydration, restricted activity, monitoring (blood pressure, weight, edema, intake, output, DTRs, patient symptoms), and daily fetal movement assessment.

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24
Q

Rubella is spread through:

A) contaminated food.
B) cat feces.
C) respiratory secretions.
D) infected mosquitoes.

A

C) respiratory secretions.

Rubella is an acquired respiratory disease and can be spread through respiratory secretions.

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25
Q

A patient who is 32 weeks pregnant has had symptoms of preterm labor and has a history of preterm delivery at 34 weeks. A fetal fibronectin test is negative. You advise her that:

A) she has a 60% chance of going into labor within the next week.
B) it is really too early in the pregnancy for this test to be of much value.
C) the result offers some reassurance that the patient will not go into labor in the next 2 weeks.
D) it is really too late in the pregnancy for this test to be of much value.

A

C) the result offers some reassurance that the patient will not go into labor in the next 2 weeks.

A negative result on a fetal fibronectin test is useful in ruling out imminent (within 14 days) preterm birth before 37 weeks’ gestation; its predictive value can be as high as 94%.

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26
Q

Which of the following individuals is at the lowest risk for developing gestational diabetes in pregnancy?

A) A 17-year-old white woman with a BMI of 30
B) A 24-year-old white woman who is pregnant for the first time
C) A 25-year-old Latina woman with a history of PCOS
D) A 32-year-old African American woman who is a vegan

A

B) A 24-year-old white woman who is pregnant for the first time

The following are risk factors for gestational diabetes: overweight or obesity, physical inactivity, history of GDM, prior LGA infant, age > 25 years, strong family history of type 2 diabetes, race/ethnicity (African American, Hispanic, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander), hypertension, elevated HDL and triglycerides, PCOS, elevated HbA1c, being treated for HIV.

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27
Q

The result of a 1-hour 50-g GCT at 28 weeks for a 34-year-old G5 P4004 was 154 mg/dL. Follow-up 100-g glucose tolerance test produced the following results: 100, 192, 185, and 160 mg/dL. The plan for this patient should include:

A) obtaining fasting glucose tests at 32 and 36 weeks to ensure that levels stay at or below 100 mg/dL.
B) referring the patient to a nutritionist to help her limit further weight gain to no more than 10 lb.
C) referring the patient to a perinatologist for periumbilical blood sampling to determine fetal blood glucose levels.
D) screening for diabetes at 6–12 weeks postpartum.

A

D) screening for diabetes at 6–12 weeks postpartum.

The patient’s 1-hour OGTT results are abnormal, and a diagnosis for gestational diabetes can be made. Thus, a screening for pregestational diabetes at 6–12 weeks postpartum is necessary.

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28
Q

The neonatal condition in which an infant is in withdrawal from opioids at birth is called:

A) NAS.
B) gestational diabetes.
C) FASD.
D) Ballard’s score.

A

A) NAS.

NAS is a condition in an which infant goes through withdrawal at birth due to fetal exposure to opioids (prescription pain relievers or heroin), barbiturates, or benzodiazepines.

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29
Q

A pregnant patient presents for the 32-week visit with no complaints. All findings from previous visits have been normal. Today she has blood pressure of 145/95 mm Hg. An expected additional finding if she has mild preeclampsia would include:

A) lower-extremity edema.
B) serum creatinine > 1.1 mg/dL.
C) right upper epigastric pain.
D) elevated liver function tests.

A

B) serum creatinine > 1.1 mg/dL.

Preeclampsia is the development of blood pressure higher than or equal to 140/90 mm Hg on two occasions at least 4 hours apart after 20 weeks’ gestation, and proteinuria greater than or equal to 300 mg per 24-hour urine collection or protein/creatinine ratio greater than or equal to 0.3 or, if other quantitative methods are unavailable, a dipstick result of 1+. In the absence of proteinuria, diagnosis parameters for preeclampsia include new-onset hypertension with any of the following:
* Thrombocytopenia: platelet count < 100,000/mcL
* Renal insufficiency: serum creatinine > 1.1 mg/dL or doubling of serum creatinine concentration without renal disease
* Impaired liver function: doubling of normal levels of liver transaminases
* Pulmonary edema
* Cerebral or visual symptoms

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30
Q

An 18-year-old female patient is 16 weeks pregnant. She has a positive chlamydia test. Appropriate management includes:

A) erythromycin base 500 mg orally QID for 7 days and ceftriaxone 125 mg IM.
B) azithromycin 1 g orally in a single dose and perform a test of cure in 3 to 4 weeks.
C) ofloxacin 300 mg orally BID for 7 days and rescreen in the third trimester.
D) spectinomycin 2 g IM now and repeat in 1 week.

A

B) azithromycin 1 g orally in a single dose and perform a test of cure in 3 to 4 weeks.

The recommended treatment for chlamydia is azithromycin 1 g PO × 1 or amoxicillin 500 mg orally TID × 7 days. Alternative regimens:
* Erythromycin base 500 mg PO QID × 7 days
* Erythromycin base 250 mg PO QID × 14 days
* Erythromycin ethylsuccinate 800 mg PO QID × 7 days
* Erythromycin ethylsuccinate 400 mg PO QID × 14 days

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31
Q

Magnesium toxicity is best managed by:

A) administering calcium gluconate.
B) dialysis.
C) administering diazepam.
D) observation.

A

A) administering calcium gluconate.

The antidote for magnesium toxicity is calcium gluconate 1 g intravenous.

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32
Q

The CDC’s recommended treatment for trichomoniasis during pregnancy is:

A) metronidazole 2 g orally.
B) clindamycin 300 mg orally BID × 7 days.
C) azithromycin 1 g orally.
D) ceftriaxone 125 mg IM.

A

A) metronidazole 2 g orally.

The treatment for trichomoniasis in pregnancy is metronidazole 2 g PO × 1 at any stage of pregnancy.

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33
Q

The varicella vaccine is recommended for:

A) all susceptible patients of reproductive age prior to conception.
B) all pregnant patients in their first trimester.
C) all pregnant patients in their last trimester.
D) all postpartum patients regardless of when their last varicella vaccine was given.

A

A) all susceptible patients of reproductive age prior to conception.

Varicella vaccination is recommended for all susceptible reproductive-age women prior to conception (at least 4 weeks before attempting pregnancy) or postpartum.

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34
Q

Ectopic pregnancy is consistent with no intrauterine sac on transvaginal ultrasound and an hCG titer of less than:

A) 100 IU/L.
B) 1500 IU/L.
C) 6500 IU/L.
D) 10,000 IU/L.

A

C) 6500 IU/L.

Ninety percent of ectopic pregnancies are associated with β-hCG levels less than 6500 IU/L.

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35
Q

Pregnancy-induced megaloblastic anemia can be treated with:

A) folic acid.
B) iron supplementation.
C) a protein-rich diet.
D) vitamin B12.

A

A) folic acid.

The underlying etiology in pregnancy-induced megaloblastic anemia is blood and bone marrow abnormalities caused by impaired DNA synthesis. Folic acid supplementation is necessary to correct this type of anemia.

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36
Q

Which of the following is the most appropriate screen for a woman who is at the end of the postpartum period and whose pregnancy was affected by gestational diabetes?

A) 50-g 1-hour oral glucose screen
B) 100-g 3-hour OGTT
C) 75-g 2-hour OGTT
D) Fasting glucose levels

A

C) 75-g 2-hour OGTT

A 75-g 2-hour OGTT should be drawn at 6–12 weeks postpartum to screen for diabetes, followed by subsequent screening for diabetes or prediabetes as part of routine primary care.

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37
Q

Hyperthyroidism in pregnancy is diagnosed by:

A) elevated FT4 levels.
B) low free T3 levels.
C) elevated TSH.
D) elevated TT4 levels.

A

A) elevated FT4 levels.

Elevated serum free thyroxine FT4or FTI levels indicate hyperthyroidism in pregnancy.

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38
Q

At an initial prenatal visit, a pregnant patient is diagnosed with bacterial vaginosis. She does not have any symptoms of vaginal infection. You tell the patient that:

A) all pregnant patients should be treated if they have asymptomatic bacterial vaginosis.
B) pregnant patients who are at risk for preterm delivery should be treated if they have asymptomatic bacterial vaginosis.
C) only pregnant patients at risk for preterm delivery should be treated for symptomatic bacterial vaginosis.
D) pregnant patients who are at risk for preterm delivery should be tested for asymptomatic bacterial vaginosis early in the third trimester.

A

B) pregnant patients who are at risk for preterm delivery should be treated if they have asymptomatic bacterial vaginosis.

The following treatment is recommended for all pregnant patients with symptoms of bacterial vaginosis: metronidazole 500 mg PO BID × 7 days or metronidazole 250 mg PO TID × 7 days or clindamycin 300 mg PO BID × 7 days.

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39
Q

Substances classified as addictive:

A) include only illegal drugs.
B) include only drugs that are inhaled or injected.
C) include both legal and illegal drugs.
D) do not include alcohol.

A

C) include both legal and illegal drugs.

Both legal and illegal substances have the potential to be addicting.

40
Q

Which of the following is a first-line imaging tool to diagnose DVT in pregnancy?

A) CT
B) MRI
C) Ultrasound
D) X-ray

A

C) Ultrasound

Ultrasound is a first-line imaging tool to diagnose DVT in pregnancy. MRI can be used if ultrasound is not conclusive and the symptoms suggest DVT. CT with contrast can be used where ultrasound and MRI are not available. X-ray is not helpful for imaging thrombosis.

41
Q

Cordocentesis may be used:

A) as an adjunct to chorionic villus sampling.
B) to obtain blood samples for a fetal fibronectin test.
C) to provide fetal blood transfusion.
D) to relieve pressure on a prolapsed cord.

A

C) to provide fetal blood transfusion.

Cordocentesis is the process in which a needle is introduced under real-time ultrasound through the maternal abdomen and then into the umbilical cord. Blood is then aspirated or blood and/or medications are introduced into the fetus.

42
Q

A patient (G2 P1001) comes for her first visit. She is concerned about the possibility of a UTI because her sister was recently hospitalized for pyelonephritis. What facts would you share to enhance her understanding?

A) UTIs do occur in approximately 10% of pregnancies.
B) Approximately 25% of women who experience UTI in pregnancy will develop pyelonephritis.
C) If the patient has a history of UTIs before pregnancy, she will be screened with a urine culture each trimester.
D) Pregnant women are typically screened for asymptomatic bacteriuria in early pregnancy.

A

D) Pregnant women are typically screened for asymptomatic bacteriuria in early pregnancy.

UTI occurs in 2% to 7% of all pregnancies. UTI may be asymptomatic (asymptomatic bacteriuria), and 25% to 30% of cases will progress to pyelonephritis if left untreated.

43
Q

Which of the following is the most common risk factor when sickle cell anemia complicates pregnancy?

A) Hypertension
B) Miscarriage
C) Perinatal mortality
D) UTI

A

D) UTI

Infections and pulmonary complications are common in pregnancies complicated by sickle cell anemia.

44
Q

An example of an autosomal recessive disease is:

A) BRCA2 breast cancer.
B) cystic fibrosis.
C) hemophilia.
D) trisomy 21.

A

B) cystic fibrosis.

An autosomal recessive trait is expressed only when both copies of the gene are the same. For example, cystic fibrosis and sickle cell anemia are genetic disorders associated with autosomal recessive traits.

45
Q

One of the screening tools for alcohol use in pregnancy is the CAGE tool. This tool asks a set of questions including:

A) Have you felt the need to cut down on your drinking?
B) How many drinks can you hold?
C) Has a friend or family member ever told you about things you said or did while you were drinking that you could not remember?
D) Do you often engage in drinking games?

A

A) Have you felt the need to cut down on your drinking?

The CAGE tool includes the following questions:
C: Have you felt the need to cut down on your drinking?
A: Have people annoyed you by criticizing your drinking?
G: Have you ever felt bad or guilty about your drinking?
E: Have you ever had a drink first thing in the morning to steady your nerves or get rid of a hangover (eye-opener)?

46
Q

As a result of an early USG, a low-lying placenta is verified. What do you tell the patient?

A) Approximately 30% of women with a low-lying placenta in early pregnancy will have placenta previa in the third trimester.
B) Approximately 30% of women have a low-lying placenta in the first trimester.
C) Regular vaginal examinations will be done in the third trimester to monitor any obstruction of the cervix.
D) Vaginal delivery is contraindicated if the patient has a marginal placenta previa.

A

B) Approximately 30% of women have a low-lying placenta in the first trimester.

One-third of women have a low-lying placenta in the first trimester. Most cases will resolve, however, so that only 1% have previa in the third trimester.

47
Q

Diabetogenic effects in pregnancy are in part related to levels of:

A) hPL.
B) estrogen.
C) placental insulinase.
D) progesterone.

A

A) hPL.

Diabetogenic effects in pregnancy are in part related to hPL, which acts as an insulin antagonist.

48
Q

Neonatal complications related to maternal tobacco use include:

A) LGA infants.
B) post-term birth.
C) IUGR.
D) rebound hypoglycemia.

A

C) IUGR.

Infant effects of maternal tobacco use include IUGR, premature birth, and SGA.

49
Q

Which of the following steps can help prevent preeclampsia from occurring in pregnancy among individuals at high risk who do not have a preexisting hypertensive disorder?

A) Prescribe oral labetalol
B) Recommend daily low-dose aspirin
C) Suggest reducing dietary sodium
D) Supplement with magnesium

A

B) Recommend daily low-dose aspirin

Low-dose aspirin, calcium, and vitamin D supplementation may be useful in preventing preeclampsia among high-risk individuals who do not have a preexisting hypertensive disorder.

50
Q

The Zika virus is primarily transmitted through:

A) contaminated food.
B) infected mosquitoes.
C) respiratory secretions.
D) cat feces.

A

B) infected mosquitoes.

The Zika virus is primarily transmitted through bites of infected mosquitoes and sexual intercourse with an infected person.

51
Q

The CDC’s recommended treatment for primary syphilis in a 10-week-pregnant patient is benzathine penicillin G 2.4 units IM:

A) × 1 dose after the first trimester.
B) × 1 dose at the time of diagnosis.
C) weekly × 3 doses.
D) at the time of diagnosis and repeat in 4 weeks if no decline in rapid plasma reagin (RPR) titer.

A

B) × 1 dose at the time of diagnosis.

The treatment for early syphilis in pregnant women is one dose of benzathine penicillin G 2.4 million units IM.

52
Q

Symmetric fetal growth restriction is caused by:

A) abnormalities in uteroplacental perfusion.
B) hypertension.
C) anemia.
D) maternal drug use.

A

D) maternal drug use.

Maternal use of tobacco, alcohol, phenytoin (Dilantin), cocaine, and heroin can cause asymmetrical fetal growth restriction, along with congenital infections and chromosomal abnormalities.

53
Q

A patient comes for the 32-week visit, and you determine that the fetus is in a breech presentation. Your plan is to:

A) send the patient to the maternal–fetal medicine unit for external cephalic version.
B) refer the patient to a perinatologist for a care decision and treatment.
C) send the patient for ultrasound to confirm breech presentation.
D) wait until 36 weeks to see if spontaneous version has occurred.

A

D) wait until 36 weeks to see if spontaneous version has occurred.

The incidence of breech presentation is 14% between 29 and 32 weeks’ gestation, and 3.5% at term. Anticipatory guidance regarding a plan for version as well as plans for persistent breech should be reviewed with the patient.

54
Q

Which of the following behaviors is most common during pregnancy?

A) Binge drinking
B) Cigarette smoking
C) Marijuana smoking
D) Occasional alcohol use

A

B) Cigarette smoking

According to the Substance Abuse and Mental Health Services Administration (2014), 15.4% of pregnant women use tobacco, compared to 5.4% who use illicit drugs, 9.4% who drink alcohol, 2.3% who engage in binge drinking, and 0.4% who engage in heavy drinking.

55
Q

Clinical manifestations of CMV in adults include:

A) a discrete pinkish-red maculopapular rash.
B) a maculopapular rash that evolves into vesicles.
C) a rash along the dermatomes.
D) CMV is usually asymptomatic.

A

D) CMV is usually asymptomatic.

Adults with CMV are usually asymptomatic. However, some may experience mononucleosis-like syndrome: fever, chills, malaise, myalgias; leukocytosis, lymphocytosis, abnormal liver function test, and lymphadenopathy.

56
Q

A patient presents with an LMP of 8 weeks ago and a positive urine pregnancy test. The patient has been having a small amount of bleeding for the past 12 hours, along with some mild abdominal cramping. A pelvic exam reveals a closed cervix and a slightly enlarged uterus. The differential diagnosis for this patient includes:

A) complete abortion and threatened abortion.
B) ectopic pregnancy and inevitable abortion.
C) ectopic pregnancy and threatened abortion.
D) incomplete abortion and inevitable abortion.

A

C) ectopic pregnancy and threatened abortion.

The differential diagnosis for bleeding in the first trimester includes implantation bleeding, threatened abortion, ectopic pregnancy, cervicitis, cervical polyps, vaginitis, trauma/intercourse, disappearing twin, and autoantibody/autoimmune disorder.

57
Q

ABO incompatibility occurs in which percentage of pregnancies?

A) 15%
B) 20% to 25%
C) 25% to 40%
D) 5% to 8%

A

B) 20% to 25%

58
Q

Which of the following tests is diagnostic rather than screening?

A) MSAFP
B) Nuchal translucency US
C) Amniocentesis
D) USG at 10 weeks

A

C) Amniocentesis

Amniocentesis is a diagnostic test for genetic evaluation or assessment of neural tube defects.

59
Q

When a patient comes for her 38-week visit, she reports that a friend gave birth last week and had a placental abruption. The patient is now concerned that she might have the same experience. What information would you share with the patient about this condition?

A) In the event of bleeding near term, 50% of cases are related to placental abruption.
B) In the third trimester, pregnant patients have a 30% chance of having a placental abruption.
C) The likelihood of having a placental abruption occur is basically zero at this time.
D) A placental abruption is associated with risk factors such as hypertension, smoking, and trauma.

A

D) A placental abruption is associated with risk factors such as hypertension, smoking, and trauma.

Risk factors for placental abruption include hypertension (chronic or gestational), trauma, smoking, cocaine use, multiparity, and uterine anomalies or tumors.

60
Q

Congenital rubella syndrome may lead to:

A) hearing impairment.
B) large for gestational age.
C) gestational diabetes.
D) sandal toe gap.

A

A) hearing impairment.

Infants affected with congenital rubella syndrome may exhibit the following effects: IUGR, cataracts, retinopathy, heart defects such as patent ductus arteriosus, and hearing impairment.

61
Q

Folic acid deficiency anemia is characterized by:

A) hemoglobin of 9 g/dL or less.
B) low ferritin levels.
C) elevated serum iron-binding capacity.
D) macrocytic erythrocytes.

A

D) macrocytic erythrocytes.

Folic acid–deficiency anemia is characterized by laboratory tests showing macrocytic erythrocytes, hypersegmentation of neutrophils, and bone marrow megaloblastic erythropoiesis.

62
Q

Which of the following statements is true concerning sickle cell hemoglobinopathies?

A) Having the sickle cell trait means that one parent has sickle cell disease.
B) Disease is present when the person inherits a sickle cell gene from each parent.
C) G6PD deficiency is a potential complication of sickle cell disease.
D) One in 100 African Americans has sickle cell trait.

A

B) Disease is present when the person inherits a sickle cell gene from each parent.

Sickle cell anemia is present when the person inherits a sickle cell gene from each parent.

63
Q

If a pregnant person with HIV does not receive antiretroviral therapy during the pregnancy, the rate of transmission to the neonate is:

A) less than 1%.
B) between 15% and 45%.
C) between 55% and 75%.
D) more than 80%.

A

B) between 15% and 45%.

Without intervention, HIV transmission rate during pregnancy is anywhere from 15% to 45%.

64
Q

Which population of women has the lowest prevalence of smoking during pregnancy?

A) African American women
B) Non-Hispanic American Indian women
C) Hispanic women
D) Non-Hispanic Asian women

A

D) Non-Hispanic Asian women

Non-Hispanic Asian women have the lowest prevalence of smoking during pregnancy (0.6%), whereas non-Hispanic American Indian or Alaska Native women have the highest prevalence (16.7%).

65
Q

What is the most accurate way to confirm a diagnosis of herpes simplex virus upon visualization of a vesicular vulvar lesion?

A) Draw a blood sample
B) Perform a punch biopsy
C) Swab the lesion
D) View with a colposcope

A

C) Swab the lesion

Swabbing the lesion will provide for the most accurate diagnosis of a visualized lesion. Drawing a serum HSV level is not specific to that lesion. A punch biopsy should not be performed on an open wound. Visualization will not necessarily yield a diagnosis.

66
Q

A 29-year-old (G4 P2012) patient is at 41 weeks today. She reports occasional cramping, denies leaking/bleeding, and states she passed a “mucus plug” yesterday. The patient asks how she will know if she is in labor because both her previous births were induced. The correct response is:

A) true labor occurs when contractions are 7–8 minutes apart and last for 45 seconds.
B) real labor is when contractions are 2–3 minutes apart and are very painful.
C) labor contractions usually become more regular and more intense over time.
D) contractions begin slowly; once they are 4–5 minutes apart, it is real labor.

A

D) contractions begin slowly; once they are 4–5 minutes apart, it is real labor.

Labor usually begins with slow contractions that gradually become more regular and closer together. When contractions are 4–5 minutes apart, this is a sign of real labor.

67
Q

Which of the following groups is at greatest risk for developing a UTI in pregnancy?

A) Adolescents
B) Women pregnant with twins
C) Women older than 35 years
D) Women with diabetes

A

D) Women with diabetes

Women with diabetes are at greatest risk for UTI. Other risk factors include sickle cell trait and pregnancy.

68
Q

A decision is made to start tocolytic therapy for a patient at 30 weeks’ gestation with preterm labor. Betamethasone IM has also been ordered because the administration of corticosteroids:

A) decreases the respiratory side effects of tocolytic drugs.
B) decreases the incidence of premature rupture of membranes.
C) enhances the effects of tocolytic drugs.
D) reduces the incidence of newborn respiratory distress syndrome.

A

D) reduces the incidence of newborn respiratory distress syndrome.

Corticosteroids, such as betamethasone and dexamethasone, are commonly used in women at risk for preterm delivery to reduce the risk of respiratory distress and cerebral hemorrhage in the newborn.

69
Q

Which of the following is an FDA-approved first-line treatment for gestational diabetes?

A) Acarbose
B) Glyburide
C) Insulin
D) Metformin

A

C) Insulin

Insulin is FDA-approved as a first-line treatment during pregnancy, as it does not cross the placenta. Although metformin may be a safe first-line treatment, it is not FDA-approved for this indication. Metformin, glyburide, and acarbose all cross the placenta and can enter the fetus.

70
Q

Which of the following anticoagulant is NOT safe in pregnancy?

A) Heparin
B) Lovenox
C) Low-dose aspirin
D) Warfarin

A

D) Warfarin

Warfarin is not safe in pregnancy due to its harmful effects on the fetus. If a patient is already using warfarin, consider switching to heparin in the preconception period or in the third trimester when fetal risk is greatest.

71
Q

Which of the following physiological and anatomic changes is associated with an increased risk of venous thrombosis in pregnancy?

A) Compression of the uterine artery
B) Decreased venous outflow
C) Decreased venous stasis
D) Hypocoagulability

A

B) Decreased venous outflow

Physiological and anatomic changes associated with an increased risk of venous thrombosis in pregnancy include hypercoagulability, increased venous stasis, decreased venous outflow, compression of the vena cava and pelvic veins by the enlarging uterus, and decreased maternal mobility.

72
Q

Maternal obstetric complications related to tobacco use may include:

A) hypotension.
B) gestational diabetes.
C) placental abruption.
D) post-term pregnancy.

A

C) placental abruption.

Maternal risks for tobacco use include preeclampsia, placental abruption, placenta previa, spontaneous abortion, ectopic pregnancy, and PROM.

73
Q

Which of the following patients should receive RhoGAM postpartum?

A) Nonsensitized Rh-negative mother with an Rh-negative baby
B) Nonsensitized-Rh negative mother with an Rh-positive baby
C) Sensitized Rh-negative mother with an Rh-negative baby
D) Sensitized Rh-negative mother with an Rh-positive baby

A

B) Nonsensitized-Rh negative mother with an Rh-positive baby

A nonsensitized Rh-negative postpartum patient with an Rh-positive baby needs RhoGAM postpartum to prevent future sensitization. A sensitized Rh-negative postpartum patient does not need RhoGAM because she is already sensitized. Likewise, a nonsensitized Rh-negative postpartum patient with an Rh-negative baby does not need RhoGAM.

74
Q

A pregnant patient has the following history: vaginal delivery at 38 weeks; spontaneous abortion at 8 weeks; elective abortion at 13 weeks; vaginal delivery at 34 weeks; two living children; now 28 weeks pregnant. This patient’s gravity and parity are:

A) G5 P1122.
B) G5 P0222.
C) G3 P2002.
D) G3 P2112.

A

A) G5 P1122.

This patient has had five total pregnancies, including her current pregnancy, one term delivery, one preterm delivery, two abortions, and two living children.

75
Q

Gestational diabetes places the fetus at risk for which of the following outcomes?

A) Cardiac anomalies
B) Neural tube defects
C) Polyhydramnios
D) Preterm birth

A

C) Polyhydramnios

GDM places the fetus at risk for IUGR, macrosomia, and polyhydramnios.

76
Q

Parvovirus is spread through:

A) contaminated food.
B) cat feces.
C) respiratory secretions.
D) touch.

A

C) respiratory secretions.

Parvovirus spreads through respiratory secretions, such as saliva, sputum, or nasal mucus; when an infected person coughs or sneezes; through blood or blood products; and vertically from pregnant person to infant.

77
Q

Symmetric intrauterine growth restriction:

A) generally becomes evident in midpregnancy.
B) is usually associated with placental abnormalities.
C) is caused by conditions that result in a reduction in cell size.
D) is a neonatal diagnosis made when the infant falls below the 10th percentile.

A

A) generally becomes evident in midpregnancy.

Symmetric growth restriction appears around 18–20 weeks and may be caused by congenital infections, chromosomal abnormalities, or maternal drug use (tobacco, alcohol, Dilantin [phenytoin], cocaine, heroin). It has an increased risk of adverse long-term sequelae.

78
Q

Normal changes of pregnancy may confound a diagnosis of appendicitis. With this possibility in mind, which of the following are critical signs or symptoms pointing to possible appendicitis in pregnancy?

A) Persistent abdominal pain and tenderness
B) Intermittent lower abdominal cramping
C) Elevated WBC level
D) Nausea and vomiting

A

A) Persistent abdominal pain and tenderness

Persistent abdominal pain and tenderness are the most critical symptoms of appendicitis.

79
Q

Which person has the greatest risk for having a macrosomic infant?

A) A person with a pre-pregnancy BMI of 19
B) A person with a partner who is 5 ft 8 in. tall and weighs 140 lb
C) A person with a previous history of gestational diabetes
D) A person and a partner who both weighed less than 6 lb at birth

A

C) A person with a previous history of gestational diabetes

The person who has the greatest risk for having a macrosomic infant is an individual with a previous history of gestational diabetes. Other risk factors relate to ethnic/racial origins, obesity, previous LGA/macrosomic neonate, previous shoulder dystocia, size of the father, birth weights of both the mother and the father, diabetes or history of gestational diabetes, previous uterine myomata, and multiparity.

80
Q

Preventive measures to avoid the spread of the parvovirus include:

A) vaccination prior to conception.
B) B19 oral medication.
C) handwashing with soap and water.
D) vaccination postpartum.

A

C) handwashing with soap and water.

There is no vaccine or medication to prevent parvovirus B19 infection. However, handwashing with soap and water and avoiding touching one’s eyes, nose, and mouth and avoiding contact with sick people may be helpful preventive measures.

81
Q

Which of the following statements concerning HIV in women is true?

A) The main route of acquiring the infection in women is IV drug use.
B) Viral load is the strongest predictor for transmission of infection to the infant during the birth process.
C) Cesarean section is the recommended route of delivery for all HIV-infected women to reduce the risk of transmission of infection to the infant.
D) Breastfeeding should be recommended only if the mother’s viral load is less than 200 copies/mL.

A

B) Viral load is the strongest predictor for transmission of infection to the infant during the birth process.

Viral load is the strongest predictor for vertical transmission of HIV.

82
Q

Which of the following factors would predispose a pregnant patient to having a baby with GBS disease?

A) History of previous GBS-positive infant
B) Bacterial vaginosis in current pregnancy
C) Frequent urinary tract infections (UTIs) prior to pregnancy
D) Streptococcal pharyngitis in the third trimester

A

A) History of previous GBS-positive infant

Risk factors for group B Streptococcus (GBS) disease include history of previous GBS-positive infant, delivering early (before 37 weeks’ gestation), developing fever during labor, having a long period between water breaking and delivery, and having a previous infant with early-onset disease.

83
Q

A patient, G2 P0010, comes for the first antepartal visit. The history indicates that the patient had a pregnancy loss at 18 weeks. She is gravely concerned that it will happen again in this pregnancy. Discussion of cervical cerclage needs to include which of the following points?

A) It will be done after 12–14 weeks and is successful 80% to 90% of the time.
B) It will be done after 16–20 weeks and is successful 80% to 90% of the time.
C) It will be done after 16–20 weeks and is successful 50% to 60% of the time.
D) It will be done after 12–14 weeks and is successful 50% to 60% of the time.

A

A) It will be done after 12–14 weeks and is successful 80% to 90% of the time.

Cervical cerclage is done after 12–14 weeks and has a success rate of 80% to 90%. There is a risk of ruptured membranes or infection. There is a need to monitor cervical length via transvaginal ultrasound.

84
Q

When faced with a patient who manifests clear evidence of being a victim of violence, your first goal is to:

A) evaluate the patient’s safety.
B) get the patient to a shelter.
C) tell the patient to press charges.
D) get photos of all injuries.

A

A) evaluate the patient’s safety.

The healthcare provider’s primary goal when caring for a patient who is abused is to evaluate the patient’s safety.

85
Q

A 32-year-old patient (G2 P1001) is Rh negative. Her first pregnancy was uneventful, and she received RhoGAM after the birth. The patient read on the Internet that problems are much more likely with the second pregnancy. The correct response is:

A) because the patient reports that she has had no transfusions since the previous birth, there is no problem.
B) the RhoGAM the patient received in the last pregnancy will prevent any problems in this pregnancy.
C) the patient was not sensitized in the first pregnancy, and you will provide monitoring and treatment to prevent it in this pregnancy.
D) it is likely that the fetus is Rh negative, so there is no real concern that she will have any problems related to this factor.

A

C) the patient was not sensitized in the first pregnancy, and you will provide monitoring and treatment to prevent it in this pregnancy.

The patient is Rh negative and received RhoGAM postpartum with her first pregnancy. She was not sensitized in the first pregnancy. The patient can be monitored and provided RhoGAM to prevent sensitization in this pregnancy.

86
Q

A pregnant patient states that she has been using marijuana (cannabis) to help with her nausea during the first trimester. What is the best advice to give to the patient?

A) “Given that marijuana has been legalized in many states, you have every right to use marijuana at your leisure.”
B) “You should wait until the second trimester to use marijuana in pregnancy.”
C) “As long as you are obtaining the marijuana from a dispensary, you should not have to worry.”
D) “The safety of marijuana use during pregnancy has not been proven.”

A

D) “The safety of marijuana use during pregnancy has not been proven.”

Because the safety of using marijuana has not been proven, ACOG recommends avoiding use of this drug while planning a pregnancy, during pregnancy, and breastfeeding.

87
Q

Genotype refers to the:

A) expression of genes present in an individual.
B) dominant genes that will be inherited by a fetus.
C) pair of genes for each characteristic inherent in an individual.
D) recessive genes that will be passed on to a fetus.

A

C) pair of genes for each characteristic inherent in an individual.

Genotype refers to the total hereditary information present in an individual—that is, the pair of genes for each characteristic.

88
Q

Asymmetric fetal growth restriction is caused by:

A) abnormalities in uteroplacental perfusion.
B) phenytoin use during the first trimester.
C) tobacco use.
D) cocaine use.

A

A) abnormalities in uteroplacental perfusion.

Asymmetrical growth restriction is caused by two main factors: reduced nutrition to the fetus and abnormalities in uteroplacental perfusion.

89
Q

A CBC in an African America woman reveals a hemoglobin concentration of 8.5 g/dL and hypochromic, microcytic erythrocytes. The most likely diagnosis is:

A) β-thalassemia.
B) iron deficiency.
C) folate deficiency.
D) sickle cell anemia.

A

B) iron deficiency.

Microcytic, hypochromic erythrocytes and low hemoglobin are typical findings with iron-deficiency anemia.

90
Q

Aneuploidy describes which of the following situations?

A) Down syndrome
B) BRCA1 and BRCA2 inheritance
C) Cystic fibrosis genes
D) Sickle cell anemia

A

A) Down syndrome

Aneuploidy is an abnormal number of chromosomes in a cell. An abnormal number of chromosomes—specifically, the presence of an extra chromosome 21—can be found in individuals with Down syndrome.

91
Q

At 28 weeks’ gestation, a patient’s Hgb is 12.4. g/dL. At the initial first-trimester visit, the Hgb was 12.8 g/dL. Management will include:

A) obtaining a CBC and ferritin level.
B) asking if the patient is having difficulty tolerating the iron supplement and changing to a different type if needed.
C) rechecking the history to see if the patient may be at risk for an inherited anemia.
D) encouraging the patient to continue getting dietary iron and taking the iron supplement.

A

D) encouraging the patient to continue getting dietary iron and taking the iron supplement.

The average hemoglobin level in pregnancy is 12.5 g/dL. The patient’s hemoglobin level is slightly below normal, and she can be encouraged to continue getting dietary iron and taking the iron supplement.

92
Q

A patient (G1 P0) comes for her 36-week visit with a piece of paper in hand: “I am really confused about this birth plan business. What am I supposed to do about my birth? Don’t I just show up when I am in labor?” How will you counsel her today?

A) “It really does not matter what you write because the hospital has its own plan.”
B) “You will need to be very detailed about each element of the birth experience so you get what you want.”
C) “The plan provides the opportunity for you to make choices about events associated with the birth.”
D) “The healthcare provider who is there when you are in labor will tell you what is best for you and how to do it.”

A

C) “The plan provides the opportunity for you to make choices about events associated with the birth.”

It is the healthcare provider’s role to listen and facilitate the patient’s expression of feelings and to provide a nonjudgmental environment.

93
Q

Infant effects of maternal cocaine use may include:

A) large for gestational age.
B) hypotonia.
C) high-pitched cry.
D) sweating.

A

C) high-pitched cry.

Infant effects of maternal cocaine use include low birth weight, small head circumference, shorter length than babies born to mothers who do not use cocaine, irritability, hyperactivity, tremors, high-pitched cry, and excessive sucking at birth.

94
Q

A 26-year-old nulliparous white woman is being admitted to the hospital in labor. She is has been previously diagnosed with opioid use disorder and has been taking Subutex during her pregnancy. Her prenatal course has been otherwise uncomplicated. For this woman, which of the following is a risk factor for thromboembolism?

A) Age
B) Pregnancy
C) Race/ethnicity
D) Subutex use

A

B) Pregnancy

This woman has the following risk factors for thromboembolism: pregnancy and hospitalization. Advanced maternal age, smoking, complications related to hypertension, and personal or family history are among risk factors generally.

95
Q

A pregnant patient who is at 42 weeks’ gestation is in the office to obtain a nonstress test. She states, “I don’t even know why I’m here getting this monitoring thing. I should be enjoying my last days of freedom before this baby comes. Why do I even need to get monitored?” The best answer is:

A) “Being pregnant beyond 42 weeks has been associated with increased morbidity and mortality. We want to assess the fetus to make sure everything is going well.”
B) “It’s a pain, I know. We just need you to not complain about it so much anymore. We are just doing our best to take care of you.”
C) “You should be thankful that you made it this far with this pregnancy.”
D) “We want to see if we can get this baby out as soon as possible.”

A

A) “Being pregnant beyond 42 weeks has been associated with increased morbidity and mortality. We want to assess the fetus to make sure everything is going well.”

A pregnancy continuing beyond 42 weeks is called post-term. Being pregnant past 42 weeks is associated with increased morbidity and mortality.

96
Q

Of the following factors, which is the most characteristic of pruritic urticarial papulae and plaques of pregnancy (PUPPP)?

A) Elevated estrogen
B) Family history
C) Inflammation
D) Multigravidity

A

C) Inflammation

PUPPP is characterized by perivasculitis.