Module 6: Energy Centers Flashcards
Mitochondria = the powerhouse of the cell
One of the other locations in the cell that contains DNA besides the nucleus
Produces most of the energy needed for the cell’s various function
Several important reactions that take place w/in it: the electron transport chain and the Krebs cycle
Endosymbiotic theory
Mitochondrias and chloroplasts = originally prokaryotes that were engulfed by eukaryotes
When these prokaryotes were swallowed by larger eukaryotic cells → both organisms received an advantage
Endosymbiotic theory: the advantage for both the prokaryotic and eukaryotic cells
Eukaryotic cells didn’t have to rely on anaerobic metabolism (I.e. glycolysis) alone anymore for energy
Prokaryotic cells now had a safe home to stay in and not be destroyed
General structure of the mitochondria
Cylindrical organelle containing an outer membrane, inner membrane, and two intermembrane spaces
Variety of proteins are in the 2 membranes → necessary for the different functions of the membranes
Inner membrane → contains cristae = many infoldings
Intermembrane space = located between the 2 membranes
Matrix = is separated from the rest of the organelle by the inner membrane
Special features of the mitochondrial membranes
Cardiolipin → special lipid in these membranes → especially prominent in the inner membrane
Many transport proteins → make both membranes selectively permeable to specific molecules (fatty acids, carnitine, etc
Inner membrane also has the proteins needed for the electron transport chain
Main functions of the mitochondria
The conduction of the Krebs cycle and the electron transport chain
Krebs cycle
Uses the pyruvate that’s made from glycolysis → turns it into acetyl CoA → used to generate ATP and NADH & FADH2 (the electron carriers)
The electron carriers are then used in the electron transport chain
Electron transport chain
Uses the electron carriers (NADH and FADH2) generated from the Krebs cycle
This process uses a protein gradient and electron transfer between the chain’s different complexes → generate energy for the cell → via oxidative phosphorylation
Oxidative phosphorylation
Generation of ATP via the use of oxidized electron carriers
Structures used in the electron transport chain
Needs complexes 1,2,3, and 4 (ATP synthase)
Each complex contains cytochromes
Some complexes create a proton gradient → used at the end by ATP synthase → form ATP
Complexes 1,2,3 and 4 (ATP synthase): importance
Required for the ETC to produce ATP from NADH and FADH2 (the electron carriers generated by the Krebs cycle)
Each complex contains cytochromes
Cytochromes
A family of colorful proteins that contain an iron atom that can accept electrons
Aid in the transfer of electrons from NADH and FADH2 → to lower energy levels → to generate ATP
Proton gradient
Created between the mitochondrial matrix and the intermembrane space due to H+ being pumped into the intermembrane space by some of the complexes
Proton gradient is used at the end of the electron transport by ATP synthase → forms ATP
Efficiency of the ETC