Mood Disorders Flashcards

1
Q

Biopsychosocial Model

A
  • Biological, social, and psychological factors interact to create a problem, lack of problem, or strength in a person
  • Not a core reason for mental health issues
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2
Q

DSM5

A
  • Current edition
  • released in 2013
  • controversial due to:
    • lower thresholds
    • poor empirical justifications for some inclusions/exclusions/changes
  • introduced some dimensional classifications
  • reliability has improved
    • some diagnoses have consistently poor reliability
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3
Q

DSM5 organization of mood disorders

A
  • Depressive Disorders
    • Major depressive disorder
    • persistent depressive disorder
    • seasonal affective disorder
    • premenstrual dysphoric disorder
    • disruptive mood regulation disorder
    • due to substance or GMC
  • Bipolar and related disorders
    • Bipolar I Disorder
    • Bipolar II Disorder
    • Cyclothymic Disorder
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4
Q

Criteria for Major Depressive Disorder

A
  • Aka Major Depressive Episodes
  • Has to meet 5 of the 9 symptoms for 2 week period
    • 1 of them has to be either:
      • depressed mood (1)
      • Anhendonia-loss of interest or pleasure (2)
    • Symptoms after the first 2 can be associated to anything
  • No maniac episode
  • not just simple bereavement
    • not a grieving process
  • Severity
  • Remission Status
  • other features:
    • psychotic
    • melancholic
    • atypical
    • anxious distress
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5
Q

Major Depressive Disorder Subtypes

A
  • Anxious distress
  • Mixed features
  • Melancholic features
  • Psychotic Features
  • Catatonic Features
  • Atypical Features
  • Seasonal Pattern
  • Peripartum onset

Don’t always use in diagnoses, but it allows us to communicate diagnosis to other professional.

  • especially what kind of symptoms patient is experiencing
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6
Q

Course of Depression

A

It can vary

  • Progression in reduction of mood
  • Onset of depressive symptoms
    • Treatment: Acute phase
      • Response/Improvement
    • Relapse
      • Symptoms return
    • Treatment: Maintenance Phase
      • remission
      • recovery
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7
Q

Demographics of Major Depressive Disorder

A
  • Demographics for lifetime prevalence
    • Sex: Women 50% more likely to experience a mood disorder over lifetime
    • Race:
      • Non-Hispanic blacks are 40% less likely
      • Hispanics-20% less likely
      • than non-Hispanic whites to experience a mood disorder during their lifetime
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8
Q

Prevalence of Major Depressive Disorder

A
  • 12 Month Prevalance
    • 6-10%
  • Lifetime prevalence
    • 16%
  • High susceptibility in young adults (18-29)
  • Low among adults over Age 65 and is difficult to diagnose:
    • less willing to report symptoms
    • Symptoms occur in the context of a serious medical illness
    • People with a history of depression are more likely to die before reaching old age
    • Rates rise in >85 y.o.
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9
Q

Persistent Depressive Disorder

A
  • Aka Dysthymia & Chronic MDD
  • Depressed mood for most of the day for at least 2 years
  • Not a less severe form
  • Risk for comorbid conditions are higher
  • Prevalence: 2%
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10
Q

Premenstrual dysphoric Disoder

A
  • Increase in distress during the premenstrual phase
  • due to extra-normative hormonal changes, significant distress or impairment
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11
Q

Disruptive Mood dysregulation disorder

A
  • Severe temper tantrums
  • out of proportion in intensity and duration to a situation
  • inconsistent with developmental level
  • diagnosis for children 6 and older
  • created to reduced bipolar diagnosis
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12
Q

Biological Factors in Depression/MDD

A
  • Genetic factors
    • 1st degree relatives 2-3x more likely
    • High concordance for mono- vs dizygotic twins
      • identical vs fraternal twins
    • Early life depression=stronger genetic basis
  • Neurotransmitter Factors:
    • norepinephrine
    • serotonin
    • dopamine
  • Sleep dysregulation
  • Neuroendocrine dysregulation
    • HPA (Hypothalmaic pituitary adrenal) hyperactiivyt or hyperreactivity
    • people who react very strongly to stress are more susceptible
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13
Q

Psychological Factors

A
  • Learned Helplessness
  • Low rate of:
    • positive reinforcement from the enviroment
    • value-driven behavior
  • Cognitive errors
  • Persistent negative thinking patterns
  • Poor social support
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14
Q

Social Factors in Depression

A
  • Poverty
  • Margnialized Group=experience few advantages and are treated poorly in social contexts
    • race
    • sexual orientation
    • etc.
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15
Q

Treatment for Depression/MDD

A
  • Antidepressant medications
    • Tricyclics
    • Monoamine oxidase inhibitors
    • Selective Serotonin Reuptake Inhibitors (SSRI’s)
    • Serotonin-Norepinephrine Reuptake Inhibitors (SNRI’s)
  • Other Somatic Therapies
    • Electroconvulsive therapy
    • Repetitive Transcranial Magnetic Stimulation (rTMS)
    • Light Therapy
    • Depp brain stimulation and Vagus Nerve Stimulation
  • Side-effects are a major drawback to all biological treatment approaches
  • Psychotherapy
    • Cognitive Behavioral Therapy
    • Behavior Therapyp (e.g. Behavioral Activation)
    • Acceptance and Commitment Therapy
  • most successful therapies are Theo nes that help the patient to change the way they think and/or way the live to facilitate mood
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16
Q

Therapeutic Approach for Depression/MDD

A
  • Behavioral or CBT approaches are evalent to meds in reducing symptoms
  • Meds work best for severe symptoms, and may not be effective with mild/moderate depressive symptoms
17
Q

Impact on Dental Care and Management

A
  • Depression–> high level of dental disease, cortisol and poorer oral care
  • Be aware of side effects from antidepressant
  • IF patient/colleague discloses persistent debilitating feeling of depression
    • recommend they seek psychotherapy or psychotherapy+meds
    • learn where sources are
18
Q

Bipolar and Related Disorders

A
  • Bipolar I Disorder
    • Manic Episode
      • elevated, expansive or irritable mood for more than one week
      • additional symptoms
      • most have depressive episodes, but not required for diagnosis
  • Bipolar II disorder
    • Depression
    • Hypomania:
      • mania with less severe symptoms
      • don’t interfere with functional, no hallucinations or delusions
  • Cyclomatic disorder
    • less severe, but more chronic bipolar condition
19
Q

Manic Episode

A
  • Distinct period of abnormal and persistently:
    • elevated, expansive or irritable mood
    • and increased activity or energy
  • 1+ weeks
  • present most of the day, nearly every day or any duration (even duration if hospitalization)
20
Q

Hypomania Episode

A
  • Distinct period of abnormal and persistent:
    • elevated, expansive, or irritable mood
    • increased activity or energy
  • Lasts at least 4 consecutive days
  • present most of the day, nearly all day
21
Q

Prevalence of Bipolar Disorder:

  • What do the last 3 factors point towards as far as factors leading to bipolar disorders?
A

12 Month Prevalence

  • BIpolar I
    • 0.6%
  • Bipolar II (USA)
    • 0.8%
  • Bipolar II (international)
    • 0.3%
  • Men & Women are equally susceptible
  • No differences among ethnic groups/cultures
  • Alot of changes in the brain
    • uncontrollable from psychosocial
    • needs medication
    • all symptoms point to biological issue
22
Q

When does Bipolar Normally develop

A

Late adolescence or early adulthood

23
Q

Factors of Bipolar Disorders

A
  • Genetic Factor:
    • 1st degree relatives: 5-10x higher rates
    • identical twins 45-75x more likely than general population
  • Brain Abnormalities
    • prefrontal cortex and amygdala
    • Striatum activity abnormal only in bipolar disorders
      • not depression
      • involved in processing of reward and reward seeking
  • Dysregulated dopamine system
  • Trigger manic episodes
    • High reward sensitivity
    • stress
    • rewarding events
    • changes in routine/sleep
24
Q

Treatment of Bipolar Disorder

A
  • Lithium
    • most effective treatment
  • SSRIs
    • less recommended bc they can cause manic episodes
  • Anticonvulsants
    • mood stabilizer
  • Atypical antipsychotics
  • Psychotherapy
    • important for adherence and symptoms management
25
Q

Bipolar Disoder: Impact on Dental Care and Management

A
  • Poorer adherence to dental care regimen
    • especially during depressive phase
  • Medication compliance=KEY
  • Hyperactive, odd, or grandiose behavior
    • indicate manic episode
    • may involve family for observation
26
Q

Suicide:

A
  • # 10 leading cause of Death in US
  • higher rates among:
    • non-hispanic whites
    • Native americans
    • indigneous people
  • 2-3x more women attempt, but Men are 4x more likely to die by suicide
    • substance abuse and guns
27
Q

Suicide: Impact on Dental Care and Management

A
  • Need additional training to assess and address suicicdal ideation wel
  • Make sure to take patients serious and listen to concerns
    • express that you are concerned
    • aknowledge their feelings
    • be non-judgemental
  • Determine if the person has a plan and access to means
  • Get healp forom other providers
    • 911
    • suicide hotline