Natural Polymers

Question 0

If we control deacetylation of chitin in NaOH ,we will get 2 types of repeat units. Name them.

Answer 0

NH2 and NHCOCH3

Question 1

How to differentiate between the 2 allomorphs?

Answer 1

infrared spectroscopy,solid state NMR ,

diffraction diagrams.

Question 2

List 9 properties of chitin

Answer 2

1. Bioadhesive
2. Biocompatible
3. Biodegradable
4. Non toxic
5. Physiological inertness
6. Hydrophilic
7. Gel forming properties( semi crystalline)
8. Anti bacterial
9. Enzyme mobilisation due to high affinity proteins.

Question 3

Application of chitin (4)

Answer 3

1. Faster wound healing. Because of the N acetyl D glucosamine also found in HA, chitin is good for wound repair and artificial skin.
2. Gels because they take a lot of water. Chitin gels for wound dressings.
3. Cell transplant to regenerate tissues.
4. DRUG RELEASE: increased speed of drug release wen added to co polymer like PGA

Question 4

Limitations of chitin(1)

Answer 4

Low mechanical strength.

Question 5

Solubilsation of chitosan in acidic medium depends on

Answer 5

Protonation of NH2 group

Question 6

Properties of chitosan (7)

Answer 6

Biodegradable
Biocompatible
3.Bioadhesive : nh2 and sugar receptors.
Non toxic 
Hydrophilic
NH and OH for H bonding
Anti bacterial

Question 7

Applications of chitosan(3)

Answer 7

1. hydrogels for DDS
2. Chitosan glycerophosohate + calcium phosphate forms an injectable self hardening system for bone repair and filling.
3. Hair keratin treatment
4. Alginate/chitosan for wound dressing