nerves Flashcards

1
Q

what makes myelin sheaths in PNS

A

schwann cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are Glia

A

90% cells in CNS

astrocytes
oligodendrocytes
microglia
ependymal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

astrocyte function

A

maintain external environment of neurons

surround blood vessels and produce BBB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Glia cells: oligodendrocytes function

A

form myelin sheaths in CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Glia cells: microglia function

A

phagocytic hoovers mopping up infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Glia cells: ependymal function

A

produce CSF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

resting membrane potential of neurons at equilibrium

A

-70mV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how is a membrane potential made

A

Na/K channel keeps coming and going equally

but leaky K+ channels let more out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

membrane potential equilibrium potential is made when

A

electrical gradient is equal and opposite to conc gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what does a graded potential do

A

depolarises cell to threshold for action potential to happen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

properties of graded potentials

A

graded- can be big or small

only act on short distances

can excite or inhibit

can be added together to make bigger

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

hyperpolarising- fast inhibition (IPSP)

A

a neurotransmitter- GABA lets Cl- in

va ionotropic receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

hyperpolarising- slow inhibition (IPSP)

A

G protein is triggered by a neurotransmitter and lets K+ out

by metabotropic receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

depolarising- fast excitation

A

neurotransmitter lets lots of Na+ in (and some K+ out)

ionotropic receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

depolarising- slow excitation

A

neurotransmitter triggers G protein and

blocks leaky K+ channels

metabotropic receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does the axon hillock do

A

fires the action potentials

17
Q

the closer to the axon hillock

A

the bigger the signal

18
Q

a signal with a slight time gap but same dendrite is called

A

temporal summation

19
Q

a time gap but different dendrites creates

A

spatial summation

20
Q

properties of an action potential

A

have a threshold

all or none

only encode intensity using frequency- not height

have a refectory period

self propagating

travel slowly

21
Q

why cant action potentials trigger backwards

A

the the refectory period

22
Q

neuromuscular junction 1

A

action potential in a motor neuron opens voltage gated Ca2+ channels- which helps make vesicles

to let out ACh

23
Q

neuromuscular junction 2

A

ACh binds to nicotinic receptors in muscle

ligand gated Na/K channels create a graded potential (end plate)

then voltage gated ligand channels create action potential

24
Q

how is ACh removed

A

acetylcholinesterase

25
Q

why does the neuromuscular junction have a safety factor

A

post junctional folds mean the endplate potential has a short distance to travel to the voltage gated Na+ channels

so no synaptic integration

26
Q

CNS synapses

A

multi synaptic

27
Q

PNS synapses

A

monosynaptic