nucleic acids Flashcards

1
Q

what are 2 examples of nucleic acids

A

DNA and RNA

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2
Q

what are nucleic acids composed of

A

monomers called nucleotides

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3
Q

what are the subunits of a nucleotide molecule and how are they joined

A

a pentose sugar attached to a phosphate and a nitrogenous base. they are joined by covalent bonds but the phosphate one is an ester

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4
Q

what is different about the nitrogenous bases on DNA and RNA

A

DNA nitrogenous bases are A, T, C, G and RNA bases are A, U, C, G. thymine is replaced with uracil

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5
Q

what are the essential ideas for translation

A

mRNA is translated into an amino acid sequence

it depends on the complementary base pairs between codons and anticodons

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6
Q

what are the purines

A

guanine and adenine

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7
Q

what are the pyrimidines

A

cytosine
thymine
uracil

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8
Q

how do purines differ from pyrimidines

A

purines have 2 rings comtaining nitrogen whereas pyrimidines only have 1

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9
Q

how many hydrogen bonds join A to T

A

2 hydrogen bonds

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10
Q

how many hydrogen bonds join G to C

A

3 hydrogen bonds

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11
Q

a purine will always pair with a pyrimidine what does this accommodate

A

as purine has 2 nitrogen containing rings and pyrimidines only have 1, when the bases pair they will always be 3 across

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12
Q

where is rna found

A

in the cytoplasm

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13
Q

why cant dna pass through the dna envelope

A

because it is too large (long and double stranded)

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14
Q

where do nucleotides that make up dna and rna exist

A

freely in the nucleus

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15
Q

how do polynucleotides form

A

via a condensation reaction between the 5 carbon phosphate group of one nucleotide and the 3 carbon hydroxyl group on the sugar of another join the two together.

A phosphodiester linkage is formed between two pentose sugars (2 covalent bonds)

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16
Q

what is the importance of complementary base pairings

A

always the same distance between each pair of bases.

ensures faithful dna replication and high fidelity of replication =accurate copy

17
Q

what does bi-directional mean

A

a mechanism that allows dna replication to proceed in opposite directions on the two strands due to the antiparallel nature of the strands

18
Q

in translation the ribosomes binds to

A

the mRNA and moves along the molecule in a 5’-3’ direction until it reaches the codon

19
Q

the mRNA is read

A

1 codon at a time

20
Q

tRNA anticodonsare what so they can what

A

are complementary to the codons on mRNA so they align.

21
Q

each tRNA molecule carries

A

a specific amino acid

22
Q

what is the end steps of translation

A

ribosomes catalyse the formation of peptide bonds between the adjacent amino acids via condensation reactions, the ribosomes moves along the mRNA strand synthesising a polypeptide chain until i reaches the stop codon, the polypeptide is then released

23
Q

what are the 5 chemical elements that make up nucleic acids

A

carbon, hydrogen , nitrogen, oxygen and phosphorus

24
Q

what is the function of nucleic acids

A

the storage and transfer of genetic information and the synthesis of proteins

25
Q

what is a phosphodiester bond

A

a covalent bond between two nucleotides resulting from a condensation reaction

26
Q

what is the function of DNA

A

to store genetic information and code for the production of polypeptides

27
Q

what is the structure of DNA

A

DNA has a double helix structure with two antiparallel polynucleotide chains twisted around each other and held together by h bonds between complementary base pairs

28
Q

what is the structure of ATP

A

the pentose sugar ribose, the nitrogenous base adenine, and three inorganic phosphate groups

29
Q

what is the function of ATP

A

an immediate source of energy for biochemical processes and synthesis of biological molecules

30
Q

how does the structure of ATP make it a good source of immediate energy

A

the bonds between the phosphate groups have a low activation energy, this means they can be easily broken, this releases energy

31
Q
A