NUtraceuticals Flashcards
what are the uses of nutraceuticals?
- improve health
- delay aging process
- preent chronic diseases
- increases life expectancy
- support the structure of function of the body
what is considered the oldest healthcare system in the world?
Ayurvedic medicine
what is the current local regulation for nutraceuticals?
FDA act of 2009 (RA 9711)
* processed food product intended to supplement the diet that bears or contains one or more of the ff dietary ingredients
what are the different natural sources of nutraceuticals?
plants
animals
microorganisms
what are the most important phytochemicals?
alkaloids
terpenes/terpenoids
indoles
isoquinolines
steroids
what is the MOA of steroid alkaloids?
believed to protect sensitized mast cells from degranulation on antigen shock
confirms immunosuppressive and membrane stabilizing effect like Na chomo
what is the MOA of Solasodine, Solasonine?
believed to protect sensitized mast cells from degranulation on antigen shock
what is the MOA of Solasodine, Solasonine?
believed to protect sensitized mast cells from degranulation on antigen shock
what is the MOA of Holaphylline, alkaloid-C, sarcovagine-D?
showed significant imunosuppressive effect on IL-2 production as well as on phytohemagglutinin stimulated T cell proliferation in a dose dependent manenr
what are the common forms of carotene?
alpha-carotene = 2nd most common form of carotene
beta-carotene = most common form of carotene
what are the therapetuic indications of Lycopene?
- antioxidant = most important
- anti-atherosclerotic
Which of the following supplements is most
advisable for a 20/M truck driver delivering goods at
night to/from NCR and Baguio City?
A. Green tea extract
B. Melatonin
C. Ginger extract
D. Lycopene
Answer: D
Lycopene is an organic pigment found in plants and vegetables which has powerful antioxidant properties which may help prevent cells from being damaged
A 40/M diagnosed with peptic ulcer disease,
inquires with his attending physician for advice regarding intake of dietary supplements. Which of the following must the physician DISCOURAGE his patient from taking?
A. Turmeric Extract
B. Calcium Carbonate
C. Vitamin A
D. Green Tea Extract
Answer: D
According to studies, green tea extract may produce COX-2 and iNOS (Inducible nitric oxide) inhibition and may increase pro-inflammatory factors that produce gastric mucosa lesions, possibly worsening PUD.
A 75-year-old male has been taking herbal
supplements to support his mental status. He now
presents with several large ecchymotic areas on his arms and legs. Which herb was he most likely taking?
A. St. John’s Wort
B. Gingko
C. Lycopene
D. Lactobacillus
Answer: B
Therapeutic claim: significant improvements in cognition and activities of daily living in patients with dementia. Toxicity: severe bleeding (ecchymosis is a manifestation of bleeding).
