Nutrition Flashcards
What is vitamin A for?
- Normal growth and reproduction
- Normal skeletal and tooth development
- Proper functioning of organs (Conjunctiva, retina, cornea)
What are the symptoms of vitamin A deficiency?
- Nyctalopia (can’t see at night/dim light)
- Xerophthalmia (dry eyes)
- Follicular hyperkeratosis, loss of appetite, impaired taste and smell, impaired equilibrium
What causes vitamin a deficiency?
Malnutrition, fat malabsorption, corticosteroid therapy
What are the functions of vitamin D?
bone formation, mineral homeostasis, regulating serum calcium
How is vitamin A given in certain regions with high deficiency rates? what does it help with?
*Two annual high doses of vitamin A are given in certain regions
*Reduces the incidence of diarrhea and measles in children and prevents blindness and hearing loss
What does vitamin D deficiency present as?
Rickets, osteoporosis , risk of falls, fracture
Fatigue
what causes vitamin D deficiency?
GI disease, Poor intake, Obesity, Gastric bypass, Renal/hepatic dysfunction, Inadequate exposure to sunlight (e.g. Northern Europe, housebound)
what are the functions of vitamin E?
- Antioxidant - protects cell membranes from oxidative damage
- Possible role in heme biosynthesis (red blood cells), steroid metabolism, collagen formation
what are the symptoms of vitamin E deficiency?
Peripheral neuropathy, intermittent claudication, muscle weakness,
hemolytic anemia
what causes vitamin E deficiency?
- Extremely rare
- Premature, very low birth weight infants
- Patients with fat malabsorption
What is the function of vitamin K?
Clotting
Bone formation
What are the symptoms of vitamin K deficiency?
Bleeding - esp in neonate, intracranial risk
What causes vitamin K deficiency?
being a neonate esp perm, intestinal disease, broad-spectrum antibiotic therapy, malabsorption syndromes, bowel resections, liver disease
What is the function of vitamin C?
- SKIN AND BONE Vital for biosynthesis of hydroxyproline, precursor of collagen, osteoid and dentin
- IRON Aids in absorption of non-heme iron from food → reduces ferric to ferrous iron
What are symptoms of vitamin C deficiency?
- Fatigue, capillary hemorrhages, petechiae, swollen hemorrhagic gums, bone changes
- Impaired wound healing
- Scurvy→if deficiency is profound/prolonged
What are the causes of vitamin C deficiency?
- Inadequate consumption
- Smoking
what is the function of vitamin B1/thiamine?
Functions:
* Oxidative decarboxylation of pyruvic acid → formation of acetyl CoA
* Critical for energy metabolism!
* Myocardial function, nerve cell function
* Carbohydrate metabolism
what are the symptoms of b1 def?
- Beriberi
*Neuromuscular symptoms: peripheral neuritis, weakness, Wernicke’s encephalopathy
*Cardiac dysfunction, edema, tachycardia, enlarged heart, ECG abnormalities
What are the causes of b1 def/beriberi?
- Inadequate diet - POLISHED RICE
- Food faddism
- Alcoholism
- Malabsorption syndromes
- Prolonged diarrhea
- Chronic diuretic therapy
What diet predisposes to beriberi?
White rice or highly refined carbohydrates
What is the response to b1/thiamine in beriberi?
Rapid - in babies in heart failure seen with hours
What is the function of B2/riboflavin?
Involved in numerous oxidative and reduction reactions including CYP450 reductase enzyme system