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Onco > Onco > Flashcards

Onco Flashcards

0
Q

Protooncogene of:

CML

A

abl

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1
Q

Fibrous tissue formation in response to neoplasm

A

Desmoplasia

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2
Q

Protooncogene of:

burkitts lymphoma

A

C-myc

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3
Q

Protooncogene of:

Follicular and undifferentiated lymphoma

A

Bcl-2

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4
Q

Protooncogene of:

Breast, ovarian and gastric carcinomas

A

Erb-b2

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5
Q

Protooncogene of:

Colon carcinoma

A

Ras

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6
Q

Protooncogene of:

Lung cancer

A

L-myc

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7
Q

Protooncogene of:

N-myc

A

Neuroblastoma

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8
Q

Protooncogene of:

MEN types II and III

A

Ret

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9
Q

Protooncogene of:

GIST

A

C-kit

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10
Q

Tsg chromosome and assoc ca?

Rb

A

13q
Retinoblastoma
Osteosarcoma

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11
Q

Tsg chromosome and assoc ca?

P15

A

Melanoma

9p

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12
Q

Tsg chromosome and assoc ca?

Wt1

A

11p

Wilms tumor

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13
Q

Tsg chromosome and assoc ca?

Dpc

A

18q pancreatic ca

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14
Q

Tsg chromosome and assoc ca?

Dcc

A

Colon ca

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15
Q

Malignancy?

Down syndrome

A

ALL AML

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16
Q

assoc ca?
Xeroderma pigmentosum
Albinism

A

Melanoma
Basal cell ca
Squamous cell ca of skin

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17
Q

assoc ca?
Chronic atrophic gastrtis
Pernicious anemia
Postsurgical gastric remnants

A

Gastric adenoca

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18
Q

assoc ca?

Tuberous sclerosus

A

Astrocytoma
Angiomyolipoma
Cardiac rhabdomyoma

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19
Q

assoc ca?

Immunodeficiency state

A

Malignant lymphoma

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20
Q

assoc ca?

Aids

A

Nonhodgkins lymphoma

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21
Q

assoc ca?

Acanthosis nigricans

A

Visceral malignancy

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22
Q

assoc ca?

Dysplastic nevus

A

Malignant melanoma

23
Q

assoc ca?

Radiation exposure

A

Sarcoma

Papillary thyroid ca

24
Q

Vinyl chloride causes

A

Liver angiosarcoma

25
Q

CCl4 causes

A

Centrilobular necrosis

Fatty liver

26
Q

Nitrosamine causes

A

Esophageal and gastric cancer

27
Q

Arsenic causes

A

Squamous cell ca of skinp

Angiosarcoma of liver

28
Q

Napthalene causes

A

Bladder ca

29
Q

Alkylating agents
Cyclophosphamide
Busulfan causes

A

Leukemia

30
Q

Flukes which causes cholangiocarcinoma

A

Clonorchis sinensis

Opisthorchcis viverrini

31
Q

Cushing syndrome results from

A

Small cell carcinoma of lung
Pancreatic carcinoma
Neural tumors

32
Q

SIADH

A

Small cell carcinoma of lung

33
Q

Hypercalcemia

A

Squamous cell carcinoma of lung
Breast carcinoma
Renal carcinoma

34
Q

Hypoglycemia results from

A

Ovarian ca

Fibrosarcoma

35
Q

Carcinoid syndrome from

A

Hepatocellular ca
Bronchial adenoma
Pancreatic ca

36
Q

Polycythemia from

A

Gastric and renal ca

Cerebellar hemangioma

37
Q

Lambert eaton syndrome

A

Lung ca

38
Q

Acanthosis nigricans

A

Visceral malignancy

EGF

39
Q

Hypertrophic osteoarthropathy

Clubbing

A

Lung ca

40
Q

Trousseau syndrome

A

Pancreatic ca and lung ca

Mucins

41
Q

Nonbacterial thrombotic endocarditis

A

Colon ca

42
Q

Red cell aplasia

A

Thymoma

43
Q

Nephrotic syndrome

A

Hodgskins lymphoma

Lung ca

44
Q

Brains mets

A 
Lots of bad stuff glia
Lung
Breast 
Skin
Kidney 
Gastrointestinal
45
Q

Liver mets

A 
Cancer sometimes penetrates benign liver 
Colon
Stomach
Pancreas
Breast
Lung
46
Q

Bone mets

A 
PTT barnum loves kids
Prostate - blastic
Thyroid - follicular
Testes 
Breast - both lytic and blastic
Lung - lytic
Kidney
47
Q

CEA

A

Colorectal ca
Pancreatic ca
Gastric ca

48
Q

AFP

A

Hepatocellular ca

Nonseminomatous GCT

49
Q

B-hcg

A

Hydatidiform mole
Choriocarcinoma
Gestional tropholastic tumor

50
Q

Ca-125

A

Ovarian epithelial tumor

51
Q

S-100

A

Melanoma
Astrocytoma
Neural tumors

52
Q

Bombesin

A

Neuroblastoma

Lung and gastric ca

53
Q

TRAP

A

Hairy cell leukemia (b-cell neoplasm)

54
Q

Ca-199

A

Pancreatic ca

Onco (2 decks)

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