Oximetry Flashcards
Hypoxemia
Oxygen deficiency in arterial blood
Hypoxia
The body or a region of the body is deprived of adequate oxygen supply
Causes of Hypoxemia
Decreased inspired oxygen, hypoventilation, shunt, or V/Q mismatch
Reasons for Hypoventilation
Respiratory center depression, neuromuscular disease, or respiratory failure
Reasons for Shunt
Pulmonary - Atelectasis, pneumonia, pulmonary edema, acute respiratory distress syndrome.
Cardiac - Patent foramen ovale
Reasons for V/Q Mismatch
Airway secretions, bronchospasm
Types of Hypoxia
Hypoxemic hypoxia, Anemic hypoxia, circulatory hypoxia, affinity hypoxia, and histotoxic hypoxia
Hypoxemic Hypoxia
Lower than normal PaO2
Anemic Hypoxia
Decreased red blood cell count, carboxyhemogobin, methemoglobin, or hemoglobinopathy
Circulatory Hypoxia
Decreased cardiac output or decreased local perfusion
Affinity Hypoxia
Decreased release of oxygen from hemoglobin to the tissues
Histotoxic Hypoxia
Cyanide poisoning
Oxyhemoglobin Dissociation Curve - Shift Left
Increases oxygen saturation for a given PO2 (increased affinity)
Oxyhemoglobin Dissociation Curve - Shift Right
Decreases oxygen saturation for a given PO2 (decreased affinity)
Oxyhemoglobin Dissociation Curve - Causes for Left Shift
Alkalosis, Hypocarbia, Hypothermia, Decreased DPG, Cabocyhemoglobin, and Fetal Hb
Oxyhemoglobin Dissociation Curve - Causes for Right Shift
CADET face Right!
Hypercarbia, Acidosis, Increased DPG, Exercise, and Hyperthermia
Content Equation
CO2 = 0.0031 * PO2 + 1.31 * O2Hb * SO2
Carboxyhemoglobin
Hemoglobin and carbon monoxide
Methemoglobin
The iron heme is Fe3+ instead of Fe 2+
Cannot bind to oxygen
Spectrophotometry
Technology that performs quantitative measurement about the transmission of light using various wavelengths of light
Lambert-Beer Law
The concentration of substances absorbing light can be determined by measuring the amount of light entering and exiting the system
CO-Oximetry
Uses arterial blood gases to determine the amounts of each form of hemoglobin including oxyhemoglobin, deoxyhemoglobin, methemoglobin, carboxyhemoglobin, fetal hemoglobin, sickle cell hemoglobin, and sulfhemoglobin
*Fractional SaO2 equation
Fractional SaO2 = O2Hb / (O2Hb + Hb + COHb + MetHb + HbF)
*Functional SaO2 equation
Functional SaO2 = O2Hb / (O2Hb + Hb)
Pulse Oximeter
A specialized spectrophotometer that uses two wavelengths of light to measure HbO2 saturation
*Pulse Oximeter wavelengths
660nm - 940nm
*What two form of hemoglobin are read as SaO2 on a conventional pulse oximeter? At what wavelength are they absorbed equally?
Oxyhemoglobin and Carboxyhemoglobin
660nm
Transmission vs. Reflectance Oximetry
Transmission - LED and photodetector on opposite sides
Reflectance - LED and photodetector on the same side; Light reflects off of the bone underneath the perfused tissue
Possible protuberances used for pulse oximetry. Which is the most common?
Finger!
Ear, tongue, nose, toes, lips, penis
Why is pulsatile flow necessary for pulse oximetry?
Pulsatile flow allows the pulse oximeter to account for the effects of absorption of light by tissue and venous blood
AC vs. DC blood flow
AC: ‘Alternating current’ - Arterial blood flow
DC: ‘Direct current’ - venous, capillary, and non pulsatile arterial blood flow
Pulse oximetry utilizes what spectrum of light?
Red and infrared
Ratio of Ratios
R = (AC 660/DC 660)/(AC 940/DC940)
What are the R values for oxyhemoglobin and deoxyhemoglobin?
OxyHb - 0.4
DeoxyHb - 3.0
When the R value is 1.0, the displayed SpO2 is what?
85%
The Isobestic Point is at what wavelength?
800nm
*Normal Value for Hb P50
26.8mmHg