P18 - Respiratory Pharmacology Flashcards

1
Q

anti-tussives MOA

A
  • suppresses medullary cough center
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2
Q

anti-tussives side effects

A
  • vomiting, depression
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3
Q

anti-tussives drugs (4)

A
  • codeine & hydrocodone
  • butorphanol
  • dextromethorphan
  • lidocaine can be used
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4
Q

anti-tussives used for

A
  • severe non-productive cough
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5
Q

modifying airway mucus consistency MOA

A
  • breaks up mucus

- increases mucus gland evacuation and production

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6
Q

modifying airway mucus consistency drugs (3)

A
  • acetylcysteine
  • bromhexine
  • dembrexin
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7
Q

home remedies work better than what drugs

A
  • drugs that modify airway mucus consistency
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8
Q

anticholinergics MOA

A
  • parasympathetic system
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9
Q

anticholinergics drugs (3)

A
  • atropine
  • butylscopolamine
  • ipratropium bromide
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10
Q

which anticholinergic is used for emergencies

A
  • atropine
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11
Q

sympathetic amines MOA

A
  • sympathetic systems
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12
Q

sympathetic amines side effects (3)

A
  • arrhythmias
  • agitation
  • nervousness
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13
Q

sympathetic amines drugs (5)

A
  • adrenaline
  • isoprenaline
  • xanthine
  • methylxanthine
  • theophylline
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14
Q

sympathetic amine used as an emergency bronchodilator

A
  • isoprenaline
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15
Q

B2-agonist MOA

A
  • activation of adenylate cyclase
  • enhances cAMP production
  • activation of PKA
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16
Q

B2-agonist side effects

A
  • decrease receptors
  • sperm abnormalities
  • tocolytic (inhibit contractions of uterus)
17
Q

B2-agonist drugs (4)

A
  • clenbuterol
  • salbutamol
  • albuterol
  • terbutaline
18
Q

what B2-agonist is forbidden in food animals

A
  • clenbuterol
19
Q

what class of drugs can also be used to increase muscle and decrease fat

A
  • B2-agonist
20
Q

mast cell stabilizers MOA

A
  • prevent release of histamine -> decrease inflammation
21
Q

mast cell stabilizers drugs (2)

A
  • sodium cromoglicate

- nedocromil sodium

22
Q

glucocorticoids MOA

A
  • reduce inflammation by inhibiting mediator release
23
Q

glucocorticoids side effects

A
  • secondary viral, fungal or bacterial infections
24
Q

glucocorticoids drugs (4)

A
  • prednisone/prednisolone
  • fluticasone
  • beclomethasone
  • dexamethasone
25
Q

which class of drugs maintain the effect of beta 2 agonist

A
  • glucocorticoids