Paedicatric Endocrinology Flashcards
What is the commonest symptom of new diabetes in children?
Nocturnal enuresis = bedwetting
What is the risk of rehydration in DKA
cerebral oedema
When is insulin commenced in DKA of a child
1 hour after IV fluids started
What is the aim HbA1c in children
less than 58mmol/mol
in those less than 1 yr duration aim for less than 48
What are the effects of poorly controlled childhood diabetes
social and emotional
physical growth sub optimal
biophysical changes of micro vascular disease
Give two primary causes of congential thyroid disease in children
gland dysplastic +/- abnormal site
inborn error of thyroid hormone metabolism
Give two secondary/tertiary causes of congential thyroid disease
pituitary disease
hypopituitarism
Give the clinical symptons of congenital thyroid disease
delayed jaundice
poor feeding but normal weight
hypotonia - umbilical hernia, constipation
skin and hair changes
What screening test should be done for congenital thyroid disease
Guthrie test
Day 5
What is the consequence of absence of thyroxine after three months
permanent developmental delay ‘cretinism’
What sign may indicate hyperthyroidism in a young person
precocious puberty
What is Addison crisis
hyponatraemia and hyperkalaemia, hypotension
What is the therapy of Addison crisis
salt and cortisol
What characteristic may appear in congenital adrenal hyperplasia
virilisation
female - ambiguous genetalie
male- precocious puberty
due to testosterone converson in CAH
