Pancreas and Gallbladder

Question 1

What secretes enzymes in prancreas?

Answer 1

exocrine cells

Question 2

what secretes HCO3 in pancreas?

Answer 2

duct cells

Question 3

what stimulates cellur transport receport pancreas cells?

Answer 3

secretin

Question 4

functions of NaHCO3?

Answer 4

protect intestinal mucosa by neutralizing protons of HCl

optimize luminal pH for pancreatic enzyme activity (7 pH)

shuts off stimulus secretin secretion (negative feedback)

Question 5

Which pancreatic enzymes act on PRO?

Answer 5

Trypsin
Chymotrypsin
Carboxypeptidase A&B
Elastase

Question 6

Which pancreatic enzymes act on fats?

Answer 6

Lipase
Phospholipase A2
Cholesterol esterase

Question 7

Which pancreatic enzymes act on carbs?

Answer 7

Amylase

Question 8

Which pancreatic enzymes act on nucleic acids?

Answer 8

`Ribonuclease

Deoxyribonuclease

Question 9

what does bile consist of?

Answer 9

water
inorganic salts – NaHCO3 NaCl
organic salts - bile salts (biliruben) 80 %

Question 10

bile salts are derived from

Answer 10

glycine and taurine

Question 11

What cause the gall bladder to contract and the sphincter of oddi to relax?

Answer 11

increase CCK secretion d/t fatty acids in duodenum

Question 12

what is the role of bile salts?

Answer 12

1. stabilize the fat emulsion (keep in small drops) (detergent function)
2. form micelles to carry end-products of digestion to absorptive cells

Question 13

True or False. Bile salts are amphipathic molecules - one containing groups with very different properties, e.g. hydrophilic and hydrophobic.

Answer 13

True

Question 14

micelles contain what?

Answer 14

monoglycerides fatty acids bile salts cholesterol phospholipids fat-soluble vitamins (A,D,E,K)

Question 15

True or False. Bile salts are absorbed into the central vein.

Answer 15

False Portal vein